4ITD
 
 | | Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation | | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*(C6G)P*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Zhang, F, Suzuki, K, Tsunoda, M, Wilkinson, O, Millington, C.L, Williams, D.M, Morishita, E.C, Takenaka, A. | | 登録日 | 2013-01-18 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations
Nucleic Acids Res., 41, 2013
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1D78
 | | HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3') | | 著者 | Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M. | | 登録日 | 1992-06-12 | | 公開日 | 1993-04-15 | | 最終更新日 | 2023-03-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A.
Acta Crystallogr.,Sect.D, 49, 1993
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2NSQ
 | | Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-06 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
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3FVY
 | | Crystal structure of human Dipeptidyl Peptidase III | | 分子名称: | CHLORIDE ION, Dipeptidyl-peptidase 3, MAGNESIUM ION, ... | | 著者 | Dong, A, Dobrovetsky, E, Seitova, A, Duncan, B, Crombet, L, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bochkarev, A, Cossar, D, Structural Genomics Consortium (SGC) | | 登録日 | 2009-01-16 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2FV8
 | | The crystal structure of RhoB in the GDP-bound state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Rho-related GTP-binding protein RhoB | | 著者 | Turnbull, A.P, Soundararajan, M, Smee, C, Johansson, C, Schoch, G, Gorrec, F, Bray, J, Papagrigoriou, E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-30 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of RhoB in the GDP-bound state
To be Published
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2ERY
 | | The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras2 | | 著者 | Salah, E, Schoch, G, Turnbull, A, Papagrigoriou, E, Soundararajan, M, Burgess, N, Elkins, J, Gileadi, C, Gileadi, O, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | | 登録日 | 2005-10-25 | | 公開日 | 2005-11-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
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1D79
 | | HIGH RESOLUTION REFINEMENT OF THE HEXAGONAL A-DNA OCTAMER D(GTGTACAC) AT 1.4 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*GP*TP*GP*TP*AP*CP*AP*C)-3') | | 著者 | Thota, N, Li, X.H, Bingman, C.A, Sundaralingam, M. | | 登録日 | 1992-06-12 | | 公開日 | 1993-04-15 | | 最終更新日 | 2023-03-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | High-resolution refinement of the hexagonal A-DNA octamer d(GTGTACAC) at 1.4 A.
Acta Crystallogr.,Sect.D, 49, 1993
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2GJS
 | | The crystal structure of human RRAD in complex with GDP | | 分子名称: | GTP-binding protein RAD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Turnbull, A.P, Yang, X, Soundararajan, M, Schoch, G, Debreczeni, J, Elkins, J.M, Gileadi, C, Berridge, G, Pantic, N, Burgess, N, Smee, C.E.A, Bray, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | | 登録日 | 2006-03-31 | | 公開日 | 2006-04-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of human RRAD in complex with GDP
To be Published
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1DNS
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1DN8
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304D
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2GTP
 | | Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | | 著者 | Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2006-04-28 | | 公開日 | 2006-05-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1CEH
 | | STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Kumar, A, Sekharudu, C, Ramakrishnan, B, Dupureur, C.M, Zhu, H, Tsai, M.-D, Sundaralingam, M. | | 登録日 | 1994-11-16 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Protein Sci., 3, 1994
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1G6K
 | | Crystal structure of glucose dehydrogenase mutant E96A complexed with NAD+ | | 分子名称: | GLUCOSE 1-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Yamamoto, K, Kurisu, G, Kusunoki, M, Tabata, S, Urabe, I, Osaki, S. | | 登録日 | 2000-11-06 | | 公開日 | 2003-08-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of stability-increasing mutants of glucose dehydrogenase
To be Published
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2H01
 | | PY00414- Plasmodium yoelii thioredoxin peroxidase I | | 分子名称: | 2-CYS PEROXIREDOXIN | | 著者 | Artz, J, Qiu, W, Min, J.R, Dong, A, Lew, J, Melone, M, Alam, Z, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-12 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of PY00414 - a Plasmodium yoelii thioredoxin peroxidase I
To be Published
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305D
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1GEE
 | | Crystal structure of glucose dehydrogenase mutant Q252L complexed with NAD+ | | 分子名称: | GLUCOSE 1-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Yamamoto, K, Kurisu, G, Kusunoki, M, Tabata, S, Urabe, I, Osaki, S. | | 登録日 | 2000-11-07 | | 公開日 | 2003-08-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of stability-increasing mutants of glucose dehydrogenase
To be Published
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306D
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2A22
 | | Structure of Vacuolar Protein Sorting 29 from Cryptosporidium Parvum | | 分子名称: | vacuolar protein sorting 29 | | 著者 | Brokx, S, Zhao, Y, Alam, Z, Lew, J, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC) | | 登録日 | 2005-06-21 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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3EFZ
 | | Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980) | | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein | | 著者 | Wernimont, A.K, Dong, A, Qiu, W, Lew, J, Wasney, G.A, Vedadi, M, Kozieradzki, I, Zhao, Y, Ren, H, Alam, Z, Lin, Y.H, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-10 | | 公開日 | 2008-09-23 | | 最終更新日 | 2012-02-22 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
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2I6T
 | | Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A | | 分子名称: | GLYCEROL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Tempel, W, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S. | | 登録日 | 2006-08-29 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Investigation into the L-lactate Dehydrogenase Domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
To be Published
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1UJL
 | | Solution Structure of the HERG K+ channel S5-P extracellular linker | | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | | 著者 | Torres, A.M, Bansal, P.S, Sunde, M, Clarke, C.E, Bursill, J.A, Smith, D.J, Bauskin, A, Breit, S.N, Campbell, T.J, Alewood, P.F, Kuchel, P.W, Vandenberg, J.I. | | 登録日 | 2003-08-05 | | 公開日 | 2003-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix
in C-type inactivation.
J.Biol.Chem., 278, 2003
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2ES0
 | | Structure of the regulator of G-protein signaling domain of RGS6 | | 分子名称: | regulator of G-protein signalling 6 | | 著者 | Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2005-10-25 | | 公開日 | 2005-11-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1VTB
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2Q58
 | | Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate | | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID | | 著者 | Chruszcz, M, Artz, J, Zheng, H, Dong, A, Dunford, J, Lew, J, Zhao, Y, Kozieradski, I, Kavanaugh, K.L, Opperman, U, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C, Bochkarev, A, Hui, R, Minor, W, Structural Genomics Consortium (SGC) | | 登録日 | 2007-05-31 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15, 2008
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