8W7E
 
 | | Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP) | | Descriptor: | 3-[(3-chlorophenyl)methyl]-6-[(4-chlorophenyl)methyl]-2,4-dihydro-1H-pyrido[2,3-c][2,7]naphthyridin-5-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | | Authors: | Jiang, J.-X, Ding, H, Chen, M.-R, Lu, M.-L, Sun, H.-Y, Xiao, Y.-B. | | Deposit date: | 2023-08-30 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
To Be Published
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8W7C
 | | Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality | | Descriptor: | 11-[(3-chlorophenyl)methyl]-7-[[4-(trifluoromethyl)phenyl]methyl]-2,5,7,11-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5-trien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | | Authors: | Jiang, J.-X, Ding, H, Lu, M.-L, Chen, M.-R, Sun, H.-Y, Xiao, Y.-B. | | Deposit date: | 2023-08-30 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality
To Be Published
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