5LQ3
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9BFN
| Cryo-EM co-structure of AcrB with the CU232 efflux pump inhibitor | Descriptor: | (2R)-1-(4-aminopiperidin-1-yl)-3-[3-(trifluoromethyl)phenoxy]propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB | Authors: | Su, C.C. | Deposit date: | 2024-04-18 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFM
| Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor | Descriptor: | (2S)-1-(3,4-dichlorophenoxy)-3-(4-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}piperidin-1-yl)propan-2-ol, Multidrug efflux pump subunit AcrB | Authors: | Su, C.C. | Deposit date: | 2024-04-18 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFH
| Cryo-EM co-structure of AcrB with the CU032 efflux pump inhibitor | Descriptor: | (2S)-1-[(3R)-3-aminopyrrolidin-1-yl]-3-(3,4-dichlorophenoxy)propan-2-ol, Multidrug efflux pump subunit AcrB | Authors: | Su, C.C. | Deposit date: | 2024-04-17 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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9BFT
| Cryo-EM co-structure of AcrB with CU244 | Descriptor: | (2S)-1-{[(1R,5R)-3-azabicyclo[3.1.0]hexan-6-yl]amino}-3-(3,5-dichlorophenoxy)propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB | Authors: | Su, C.C. | Deposit date: | 2024-04-18 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
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6OWS
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6OR2
| MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, DODECYL-BETA-D-MALTOSIDE, Membrane protein, ... | Authors: | Su, C.-C. | Deposit date: | 2019-04-29 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine. Proc.Natl.Acad.Sci.USA, 116, 2019
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7N6B
| Structure of MmpL3 reconstituted into lipid nanodisc in the TMM bound state | Descriptor: | 6-O-[(2S)-2-{(1S)-18-[(1R,2R)-2-hexylcyclopropyl]-1-hydroxyoctadecyl}tricosanoyl]-alpha-D-glucopyranosyl alpha-D-glucopyranoside, MmpL3 transporter | Authors: | Su, C.C, Yu, E. | Deposit date: | 2021-06-08 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. Plos Biol., 19, 2021
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8EL9
| Cryo-EM structure of human catalase | Descriptor: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Su, C.C. | Deposit date: | 2022-09-23 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.27 Å) | Cite: | Cryo-EM structure of human catalase To Be Published
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6WTI
| The Cryo-EM structure of the ubiquinol oxidase from Escherichia coli | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome o ubiquinol oxidase, ... | Authors: | Su, C.-C. | Deposit date: | 2020-05-02 | Release date: | 2021-01-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins. Nat.Methods, 18, 2021
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8EMR
| Cryo-EM structure of human liver glucosidase II | Descriptor: | CALCIUM ION, Glucosidase 2 subunit beta, Neutral alpha-glucosidase AB, ... | Authors: | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | Deposit date: | 2022-09-28 | Release date: | 2023-05-10 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EMT
| Cryo-EM analysis of the human aldehyde oxidase from liver | Descriptor: | Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | Deposit date: | 2022-09-28 | Release date: | 2023-05-10 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EMS
| Cryo-EM structure of human liver glycogen phosphorylase | Descriptor: | Glycogen phosphorylase, liver form, PYRIDOXAL-5'-PHOSPHATE | Authors: | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | Deposit date: | 2022-09-28 | Release date: | 2023-05-10 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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7K7M
| Crystal Structure of a membrane protein | Descriptor: | Drug exporters of the RND superfamily-like protein, alpha-D-glucopyranose-(1-1)-6-O-decanoyl-alpha-D-glucopyranose | Authors: | Su, C.-C. | Deposit date: | 2020-09-23 | Release date: | 2021-09-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. Plos Biol., 19, 2021
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7JZ6
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7JZH
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5T0O
| Crystal Structure of a membrane protein | Descriptor: | CmeB | Authors: | Su, C.-C, Yu, E.W. | Deposit date: | 2016-08-16 | Release date: | 2017-09-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump. Nat Commun, 8, 2017
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7K8C
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7K8D
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7K8A
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7K8B
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8T3U
| Cryo-EM Analysis of AE1 Structure in 100 mM NaCl Buffer: Form2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Su, C.C. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Cryo-EM structure of the band 3 anion transport protein To Be Published
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8T47
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8T45
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8T44
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