5NGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ngx by Molmil](/molmil-images/mine/5ngx) | The 1.06 A resolution structure of the L16G mutant of ferric cytochrome c prime from Alcaligenes xylosoxidans, complexed with nitrite | 分子名称: | Cytochrome c', GLYCEROL, HEME C, ... | 著者 | Strange, R, Hough, M, Kekelli, D, Horrell, S, Moreno Chicano, T. | 登録日 | 2017-03-20 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory. Inorg.Chem., 56, 2017
|
|
5NC0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nc0 by Molmil](/molmil-images/mine/5nc0) | The 0.91 A resolution structure of the L16G mutant of cytochrome c prime from Alcaligenes xylosoxidans, complexed with nitric oxide | 分子名称: | 1,2-ETHANEDIOL, Cytochrome c', HEME C, ... | 著者 | Strange, R, Hough, M, Antonyuk, S, Rustage, N. | 登録日 | 2017-03-02 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | 主引用文献 | Distinguishing Nitro vs Nitrito Coordination in Cytochrome c' Using Vibrational Spectroscopy and Density Functional Theory. Inorg Chem, 56, 2017
|
|
4Y8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y8e by Molmil](/molmil-images/mine/4y8e) | PA3825-EAL Ca-Apo Structure | 分子名称: | CALCIUM ION, PA3825 EAL | 著者 | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | 登録日 | 2015-02-16 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Structure of PA3825 from P. aeruginosa bound to cyclic di-GMP and pGpG: new insights for a potential three-metal catalytic mechanism of EAL domains To Be Published
|
|
4Y9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y9o by Molmil](/molmil-images/mine/4y9o) | PA3825-EAL Metal-Free-Apo Structure - Manganese Co-crystallisation | 分子名称: | PA3825-EAL, PHOSPHATE ION | 著者 | Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A. | 登録日 | 2015-02-17 | 公開日 | 2016-09-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | MucR and PA3825 EAL-phosphodiesterase domains from Pseudomonas aeruginosa suggest roles for three metals in the active site To Be Published
|
|
4Y9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y9n by Molmil](/molmil-images/mine/4y9n) | PA3825-EAL Metal-Free-Apo Structure - Magnesium Co-crystallisation | 分子名称: | PA3825-EAL, PHOSPHATE ION | 著者 | Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A. | 登録日 | 2015-02-17 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of PA3825 from P. aeruginosa bound to cyclic di-GMP and pGpG: new insights for a potential three-metal catalytic mechanism of EAL domains To Be Published
|
|
1OZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ozt by Molmil](/molmil-images/mine/1ozt) | Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | 登録日 | 2003-04-09 | 公開日 | 2003-05-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS Nat.Struct.Biol., 10, 2003
|
|
1OZU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ozu by Molmil](/molmil-images/mine/1ozu) | Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | 登録日 | 2003-04-09 | 公開日 | 2003-05-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS Nat.Struct.Biol., 10, 2003
|
|
4Y9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y9m by Molmil](/molmil-images/mine/4y9m) | PA3825-EAL Metal-Free-Apo Structure | 分子名称: | PA3825-EAL, PHOSPHATE ION | 著者 | Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A. | 登録日 | 2015-02-17 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. Sci Rep, 7, 2017
|
|
4Y9P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y9p by Molmil](/molmil-images/mine/4y9p) | PA3825-EAL Ca-CdG Structure | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, PA3825-EAL | 著者 | Bellini, D, Horrell, S, Wagner, A, Strange, R, Walsh, M.A. | 登録日 | 2015-02-17 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | MucR and PA3825 EAL-phosphodiesterase domains from Pseudomonas aeruginosa suggest roles for three metals in the active site To Be Published
|
|
5MKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mkg by Molmil](/molmil-images/mine/5mkg) | PA3825-EAL Ca-CdG Structure | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Diguanylate phosphodiesterase | 著者 | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | 登録日 | 2016-12-04 | 公開日 | 2016-12-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. Sci Rep, 7, 2017
|
|
5MF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mf5 by Molmil](/molmil-images/mine/5mf5) | PA3825-EAL Mg-CdG Structure | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate phosphodiesterase, MAGNESIUM ION | 著者 | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | 登録日 | 2016-11-17 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. Sci Rep, 7, 2017
|
|
5N8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n8g by Molmil](/molmil-images/mine/5n8g) | Serial Cu nitrite reductase structures at elevated cryogenic temperature, 240K. Dataset 2. | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, SULFATE ION | 著者 | Horrell, S, Kekilli, D, Hough, M, Strange, R. | 登録日 | 2017-02-23 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase. IUCrJ, 4, 2017
|
|
5N8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n8h by Molmil](/molmil-images/mine/5n8h) | Serial Cu nitrite reductase structures at elevated cryogenic temperature, 240K. Dataset 3. | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, SULFATE ION | 著者 | Horrell, S, Kekilli, D, Hough, M, Strange, R. | 登録日 | 2017-02-23 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase. IUCrJ, 4, 2017
|
|
5N8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n8f by Molmil](/molmil-images/mine/5n8f) | Serial Cu nitrite reductase structures at elevated cryogenic temperature, 240K. Dataset 1. | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, SULFATE ION | 著者 | Horrell, S, Kekilli, D, Hough, M, Strange, R. | 登録日 | 2017-02-23 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase. IUCrJ, 4, 2017
|
|
5N8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n8i by Molmil](/molmil-images/mine/5n8i) | Serial Cu nitrite reductase structures at elevated cryogenic temperature, 100K reference dataset. | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, MALONATE ION | 著者 | Horrell, S, Kekilli, D, Hough, M, Strange, R. | 登録日 | 2017-02-23 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase. IUCrJ, 4, 2017
|
|
5MFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mfu by Molmil](/molmil-images/mine/5mfu) | PA3825-EAL Mn-pGpG Structure | 分子名称: | Diguanylate phosphodiesterase, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | 登録日 | 2016-11-18 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. Sci Rep, 7, 2017
|
|
2WKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wko by Molmil](/molmil-images/mine/2wko) | Structure of metal loaded Pathogenic SOD1 Mutant G93A. | 分子名称: | COPPER (II) ION, IODIDE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | 著者 | Antonyuk, S.V, Galaleldeen, A, Strange, R, Whitson, L, Narayana, N, Taylor, A, Schuermann, J.P, Holloway, S.P, Hasnain, S.S, Hart, P.J. | 登録日 | 2009-06-16 | 公開日 | 2009-11-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A. Arch.Biochem.Biophys., 492, 2009
|
|
2XLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xlv by Molmil](/molmil-images/mine/2xlv) | Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124F variant with bound NO | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE | 著者 | Hough, M.A, Antonyuk, S.V, Strange, R, Hasnain, S.S. | 登録日 | 2010-07-22 | 公開日 | 2010-11-10 | 最終更新日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket. J.Mol.Biol., 405, 2011
|
|
2XLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xlm by Molmil](/molmil-images/mine/2xlm) | Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous recombinant native with bound NO | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE, ... | 著者 | Hough, M.A, Antonyuk, S.V, Strange, R, Hasnain, S.S. | 登録日 | 2010-07-21 | 公開日 | 2010-11-10 | 最終更新日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket. J.Mol.Biol., 405, 2011
|
|
5CXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cxz by Molmil](/molmil-images/mine/5cxz) | SYK catalytic domain complexed with naphthyridine inhibitor | 分子名称: | CHLORIDE ION, GLYCEROL, N-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine, ... | 著者 | Thoma, G, Veenstra, S, Strang, R, Blanz, J, Vangrevelinghe, E, Berghausen, J, Lee, C.C, Zerwes, H.-G. | 登録日 | 2015-07-29 | 公開日 | 2015-09-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015
|
|