4P7H
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4PA0
| Omecamtiv Mercarbil binding site on the Human Beta-Cardiac Myosin Motor Domain | Descriptor: | GLYCEROL, Myosin-7,Green fluorescent protein, methyl 4-(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}benzyl)piperazine-1-carboxylate | Authors: | Winkelmann, D.A, Miller, M.T, Stock, A.M. | Deposit date: | 2014-04-06 | Release date: | 2015-07-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for drug-induced allosteric changes to human beta-cardiac myosin motor activity. Nat Commun, 6, 2015
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4GT8
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1NEP
| Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epididymal secretory protein E1, PHOSPHATE ION | Authors: | Friedland, N, Liou, H.-L, Lobel, P, Stock, A.M. | Deposit date: | 2002-12-11 | Release date: | 2003-01-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of a Cholesterol-binding Protein Deficient in Niemann-Pick Type C2 Disease Proc.Natl.Acad.Sci.USA, 100, 2003
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1ZTY
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1ZU0
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2HKA
| Crystal structure of bovine NPC2 and cholesterol sulfate complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... | Authors: | Xu, S, Gu, L, Benoff, B, Stock, A.M. | Deposit date: | 2006-07-03 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease J.Biol.Chem., 282, 2007
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2GWR
| Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis | Descriptor: | CALCIUM ION, DNA-binding response regulator mtrA, GLYCEROL | Authors: | Friedland, N, Mack, T.R, Yu, M, Bursey, E.H, Hung, L.W, Stock, A.M, Waldo, G.S, Terwilliger, T.C. | Deposit date: | 2006-05-05 | Release date: | 2006-05-23 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation. Biochemistry, 46, 2007
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1TPW
| TRIOSEPHOSPHATE ISOMERASE DRINKS WATER TO KEEP HEALTHY | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | Deposit date: | 1994-11-07 | Release date: | 1995-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The role of water in the catalytic efficiency of triosephosphate isomerase. Biochemistry, 38, 1999
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1OPC
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2FLK
| Crystal structure of CheY in complex with CheZ(200-214) solved from a F432 crystal grown in CAPS (pH 10.5) | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, C-terminal 15-mer from Chemotaxis protein cheZ, Chemotaxis protein cheY, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-06 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol., 359, 2006
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2FMH
| Crystal structure of Mg2+ and BeF3- bound CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Tris (pH 8.4) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BERYLLIUM TRIFLUORIDE ION, C-terminal 15-mer from Chemotaxis protein cheZ, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-09 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol., 359, 2006
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2FKA
| Crystal structure of Mg(2+) and BeF(3)(-)-bound CheY in complex with CheZ(200-214) solved from a F432 crystal grown in CAPS (pH 10.5) | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, BERYLLIUM TRIFLUORIDE ION, C-terminal 15-mer from Chemotaxis protein cheZ, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-04 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol., 359, 2006
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2FLW
| Crystal structure of Mg2+ and BeF3- ound CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Hepes (pH 7.5) | Descriptor: | BERYLLIUM TRIFLUORIDE ION, C-terminal 15-mer from Chemotaxis protein cheZ, Chemotaxis protein cheY, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-06 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol., 359, 2006
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2FMI
| Crystal structure of CheY in complex with CheZ 200-214 solved from a F432 crystal grown in Tris (pH 8.4) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-terminal 15-mer from Chemotaxis protein cheZ, Chemotaxis protein cheY, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-09 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation. J.Mol.Biol., 359, 2006
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2FMF
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2FMK
| Crystal structure of Mg2+ and BeF3- bound CheY in complex with CheZ 200-214 solved from a P2(1)2(1)2 crystal grown in MES (pH 6.0) | Descriptor: | BERYLLIUM TRIFLUORIDE ION, C-terminal 15-mer from Chemotaxis protein cheZ, Chemotaxis protein cheY, ... | Authors: | Guhaniyogi, J, Robinson, V.L, Stock, A.M. | Deposit date: | 2006-01-09 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation J.Mol.Biol., 359, 2006
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1DZ6
| ferrous p450cam from pseudomonas putida | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | Authors: | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | Deposit date: | 2000-02-18 | Release date: | 2000-03-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution Science, 287, 2000
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1DZ4
| ferric p450cam from pseudomonas putida | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | Authors: | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | Deposit date: | 2000-02-16 | Release date: | 2000-07-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution Science, 287, 2000
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1DZ8
| oxygen complex of p450cam from pseudomonas putida | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | Authors: | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | Deposit date: | 2000-02-18 | Release date: | 2000-03-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution Science, 287, 2000
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1DZ9
| Putative oxo complex of P450cam from Pseudomonas putida | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | Authors: | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | Deposit date: | 2000-02-18 | Release date: | 2000-03-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution Science, 287, 2000
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1A2O
| STRUCTURAL BASIS FOR METHYLESTERASE CHEB REGULATION BY A PHOSPHORYLATION-ACTIVATED DOMAIN | Descriptor: | CHEB METHYLESTERASE | Authors: | Djordjevic, S, Goudreau, P.N, Xu, Q, Stock, A.M, West, A.H. | Deposit date: | 1998-01-06 | Release date: | 1998-04-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain. Proc.Natl.Acad.Sci.USA, 95, 1998
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1AF7
| CHER FROM SALMONELLA TYPHIMURIUM | Descriptor: | CHEMOTAXIS RECEPTOR METHYLTRANSFERASE CHER, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Djordjevic, S, Stock, A.M. | Deposit date: | 1997-03-22 | Release date: | 1998-01-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine. Structure, 5, 1997
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1BC5
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1TPU
| S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | Deposit date: | 1994-11-07 | Release date: | 1995-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase. Biochemistry, 35, 1996
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