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PDB: 11 件

4CMQ
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BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-17
公開日2014-02-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
7RZY
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BU of 7rzy by Molmil
CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC)
著者Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H.
登録日2021-08-28
公開日2022-06-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
7UFI
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BU of 7ufi by Molmil
VchTnsC AAA+ ATPase with DNA, single heptamer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ...
著者Fernandez, I.S, Sternberg, S.H.
登録日2022-03-22
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
7UFM
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BU of 7ufm by Molmil
VchTnsC AAA+ with DNA (double heptamer)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (36-MER), VchTnsC
著者Fernandez, I.S, Sternberg, S.H.
登録日2022-03-22
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
6PIG
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BU of 6pig by Molmil
V. cholerae TniQ-Cascade complex, closed conformation
分子名称: RNA (60-MER), TniQ monomer 1, TniQ monomer 2, ...
著者Halpin-Healy, T, Klompe, S, Sternberg, S.H.
登録日2019-06-26
公開日2019-10-02
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Nature, 577, 2020
4AL6
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BU of 4al6 by Molmil
Crystal structure of the S148ACsy4-crRNA complex
分子名称: CRRNA, 5'-R(CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP* CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
6PIJ
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BU of 6pij by Molmil
Target DNA-bound V. cholerae TniQ-Cascade complex, closed conformation
分子名称: Non-targeting strand ssDNA, Targeting strand ssDNA, TniQ monomer 2, ...
著者Halpin-Healy, T, Klompe, S, Sternberg, S.H.
登録日2019-06-26
公開日2019-10-02
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Nature, 577, 2020
4AL5
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BU of 4al5 by Molmil
Crystal structure of the Csy4-crRNA product complex
分子名称: 5'-R(*UP*UP*CP*AP*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP *GP*GP*CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE, GLYCEROL
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4AL7
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BU of 4al7 by Molmil
Crystal structure of the Csy4-minimal crRNA complex
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*AP*G)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
6PIF
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BU of 6pif by Molmil
V. cholerae TniQ-Cascade complex, open conformation
分子名称: Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ...
著者Halpin-Healy, T, Klompe, S, Sternberg, S.H.
登録日2019-06-26
公開日2019-10-02
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Nature, 577, 2020
4CMP
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BU of 4cmp by Molmil
Crystal structure of S. pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-16
公開日2014-02-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014

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