5CPW
 
 | | Crystal structure of murine polyomavirus PTA strain VP1 in complex with the GT1a glycan | | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | | Authors: | Liaci, A.M, Buch, M.H.C, Neu, U, Stehle, T. | | Deposit date: | 2015-07-21 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity.
Plos Pathog., 11, 2015
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4MJ1
 | | unliganded BK Polyomavirus VP1 pentamer | | Descriptor: | CHLORIDE ION, GLYCEROL, VP1 capsid protein | | Authors: | Neu, U, Stroh, L.J, Stehle, T. | | Deposit date: | 2013-09-03 | | Release date: | 2013-11-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus.
Plos Pathog., 9, 2013
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6HKU
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6H4F
 | | TarP-3RboP | | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2018-07-21 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
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6H21
 | | TarP-UDP-GlcNAc-Mn | | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2018-07-12 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
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6HNQ
 | | TarP-6RboP-(CH2)6NH2 | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable ss-1,3-N-acetylglucosaminyltransferase, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2018-09-17 | | Release date: | 2018-10-24 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
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6HKV
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2O39
 | | Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | | Descriptor: | CALCIUM ION, Fiber protein, Membrane cofactor protein, ... | | Authors: | Persson, D.B, Reiter, D.M, Arnberg, N, Stehle, T. | | Deposit date: | 2006-12-01 | | Release date: | 2007-01-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Adenovirus type 11 binding alters the conformation of its receptor CD46.
Nat.Struct.Mol.Biol., 14, 2007
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6H4M
 | | TarP-UDP-GlcNAc-3RboP | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable ss-1,3-N-acetylglucosaminyltransferase, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2018-07-22 | | Release date: | 2018-09-26 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
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7PA8
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7PA6
 | | JC polyomavirus VP1 in complex with scFv 27C11 | | Descriptor: | Major capsid protein VP1, scFv 27C11 antibody heavy chain | | Authors: | Harprecht, C, Stroeh, L.J, Nagel, F, Freytag, J, Stehle, T. | | Deposit date: | 2021-07-29 | | Release date: | 2023-02-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural characterization of human neutralizing antibodies against JC and BK polyomavirus
To Be Published
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7PA9
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4GR5
 | | Crystal structure of SlgN1deltaAsub in complex with AMPcPP | | Descriptor: | CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, L(+)-TARTARIC ACID, ... | | Authors: | Herbst, D.A, Zocher, G, Stehle, T. | | Deposit date: | 2012-08-24 | | Release date: | 2012-11-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes.
J.Biol.Chem., 288, 2013
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7QD7
 | | TarM(Se)_G117R | | Descriptor: | CHLORIDE ION, GLYCEROL, PENTAETHYLENE GLYCOL, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2021-11-26 | | Release date: | 2023-05-10 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition.
Sci Adv, 9, 2023
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7QH9
 | | TarM(Se)_G117R-4RboP | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, TarM(Se)_G117R-4RboP, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2021-12-10 | | Release date: | 2023-05-10 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.689 Å) | | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition.
Sci Adv, 9, 2023
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7QNT
 | | TarM(Se) native | | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | Authors: | Guo, Y, Stehle, T. | | Deposit date: | 2021-12-22 | | Release date: | 2023-05-10 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition.
Sci Adv, 9, 2023
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4GR4
 | | Crystal structure of SlgN1deltaAsub | | Descriptor: | CHLORIDE ION, Non-ribosomal peptide synthetase | | Authors: | Herbst, D.A, Zocher, G, Stehle, T. | | Deposit date: | 2012-08-24 | | Release date: | 2012-11-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes.
J.Biol.Chem., 288, 2013
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7ZH8
 | | DYRK1a in Complex with a Bromo-Triazolo-Pyridine | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | | Authors: | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | | Deposit date: | 2022-04-05 | | Release date: | 2022-11-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes.
J.Med.Chem., 65, 2022
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8A92
 | | p53-Y220C Core Domain in Complex with a Bromo-trifluoro-pyrazole-amine | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine, Cellular tumor antigen p53, ... | | Authors: | Stahlecker, J, Braun, M.B, Stehle, T, Boeckler, F.M. | | Deposit date: | 2022-06-27 | | Release date: | 2022-11-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C.
Rsc Med Chem, 13, 2022
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4L68
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3S3L
 | | Crystal Structure of CerJ from Streptomyces tendae | | Descriptor: | ACETATE ION, CHLORIDE ION, CerJ | | Authors: | Zocher, G, Hertweck, C, Bretschneider, T, Stehle, T. | | Deposit date: | 2011-05-18 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
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4E0T
 | | Crystal structure of CdpNPT in its unbound state | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cyclic dipeptide N-prenyltransferase, ... | | Authors: | Schuller, J.M, Zocher, G, Stehle, T. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity.
J.Mol.Biol., 422, 2012
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4EE6
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4EE7
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3T8E
 | | Crystal structure of CerJ from Streptomyces tendae soaked with CerviK | | Descriptor: | ACETATE ION, CerJ | | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | | Deposit date: | 2011-08-01 | | Release date: | 2011-12-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
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