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PDB: 50 results

1XU1
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The crystal structure of APRIL bound to TACI
Descriptor: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B
Authors:Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
Deposit date:2004-10-25
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
1KCO
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Structure of e131 Zeta Peptide, a Potent Antagonist of the High-Affinity IgE Receptor
Descriptor: e131 Zeta Peptide
Authors:Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
Deposit date:2001-11-09
Release date:2002-03-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KCN
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Structure of e109 Zeta Peptide, an Antagonist of the High-Affinity IgE Receptor
Descriptor: e109 zeta peptide
Authors:Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
Deposit date:2001-11-09
Release date:2002-03-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1U5Z
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The Crystal structure of murine APRIL, pH 8.5
Descriptor: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5X
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Crystal structure of murine APRIL at pH 5.0
Descriptor: Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Y
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Crystal structure of murine APRIL, pH 8.0
Descriptor: Tumor necrosis factor ligand superfamily member 13
Authors:Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1XU2
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The crystal structure of APRIL bound to BCMA
Descriptor: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17
Authors:Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
Deposit date:2004-10-25
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
1XUT
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Solution structure of TACI-CRD2
Descriptor: Tumor necrosis factor receptor superfamily member 13B
Authors:Hymowitz, S.G, Patel, D.R, Wallweber, H.J, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
Deposit date:2004-10-26
Release date:2004-11-09
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.
J.Biol.Chem., 280, 2005
1VGH
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HEPARIN-BINDING DOMAIN FROM VASCULAR ENDOTHELIAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor: VASCULAR ENDOTHELIAL GROWTH FACTOR-165
Authors:Fairbrother, W.J, Champe, M.A, Christinger, H.W, Keyt, B.A, Starovasnik, M.A.
Deposit date:1997-12-17
Release date:1998-04-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the heparin-binding domain of vascular endothelial growth factor.
Structure, 6, 1998
1JPY
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Crystal structure of IL-17F
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hymowitz, S.G, Filvaroff, E.H, Yin, J, Lee, J, Cai, L, Risser, P, Maruoka, M, Mao, W, Foster, J, Kelley, R, Pan, G, Gurney, A.L, de Vos, A.M, Starovasnik, M.A.
Deposit date:2001-08-03
Release date:2001-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20, 2001
4DST
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Descriptor: 1,2-ETHANEDIOL, 2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine, ACETATE ION, ...
Authors:Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
Deposit date:2012-02-19
Release date:2012-04-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSO
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ...
Authors:Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
Deposit date:2012-02-19
Release date:2012-04-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSU
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Descriptor: BENZIMIDAZOLE, GTPase KRas, isoform 2B, ...
Authors:Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
Deposit date:2012-02-19
Release date:2012-04-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSN
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BU of 4dsn by Molmil
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Descriptor: 1,2-ETHANEDIOL, GTPase KRas, isoform 2B, ...
Authors:Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
Deposit date:2012-02-19
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
1LE1
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NMR Structure of Tryptophan Zipper 2: A stable, Monomeric Beta-Hairpin with a Type I' Turn
Descriptor: Tryptophan Zipper 2
Authors:Cochran, A.G, Skelton, N.J, Starovasnik, M.A.
Deposit date:2002-04-09
Release date:2002-04-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Tryptophan zippers: stable, monomeric beta -hairpins.
Proc.Natl.Acad.Sci.USA, 98, 2001
1LE0
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NMR structure of Tryptophan Zipper 1: a stable, monomeric beta-hairpin with a type II' turn
Descriptor: Tryptophan Zipper 1
Authors:Cochran, A.G, Skelton, N.J, Starovasnik, M.A.
Deposit date:2002-04-09
Release date:2002-04-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Tryptophan zippers: stable, monomeric beta -hairpins.
Proc.Natl.Acad.Sci.USA, 98, 2001
1LE3
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BU of 1le3 by Molmil
NMR Structure of Tryptophan Zipper 4: A Stable Beta-Hairpin Peptide Based on the C-terminal Hairpin of the B1 Domain of Protein G
Descriptor: Tryptophan Zipper 4
Authors:Cochran, A.G, Skelton, N.J, Starovasnik, M.A.
Deposit date:2002-04-09
Release date:2002-04-24
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Tryptophan zippers: stable, monomeric beta -hairpins.
Proc.Natl.Acad.Sci.USA, 98, 2001
4EUU
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Structure of BX-795 Complexed with Human TBK1 Kinase Domain Phosphorylated on Ser172
Descriptor: GLYCEROL, IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, ...
Authors:Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C.
Deposit date:2012-04-25
Release date:2012-05-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DKE
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Crystal Structure of Human Interleukin-34 Bound to FAb1.1
Descriptor: FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ...
Authors:Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
Deposit date:2012-02-03
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4EUT
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Structure of BX-795 Complexed with Unphosphorylated Human TBK1 Kinase-ULD Domain
Descriptor: IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, SULFATE ION, ...
Authors:Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C.
Deposit date:2012-04-25
Release date:2012-05-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
1JBF
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Hairpin Peptide that Inhibits IgE Activity by Binding to the High Affinity IgE Receptor
Descriptor: IGE06
Authors:Nakamura, G.R, Starovasnik, M.A, Reynolds, M.E, Lowman, H.B.
Deposit date:2001-06-04
Release date:2001-08-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A novel family of hairpin peptides that inhibit IgE activity by binding to the high-affinity IgE receptor.
Biochemistry, 40, 2001
4DKF
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Crystal Structure of Human Interleukin-34 Bound to FAb2
Descriptor: FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ...
Authors:Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
Deposit date:2012-02-03
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
1DGN
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SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION
Descriptor: ICEBERG (PROTEASE INHIBITOR)
Authors:Humke, E.W, Shriver, S.K, Starovasnik, M.A, Fairbrother, W.J, Dixit, V.M.
Deposit date:1999-11-24
Release date:2000-10-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:ICEBERG: a novel inhibitor of interleukin-1beta generation.
Cell(Cambridge,Mass.), 103, 2000
4DKD
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Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ...
Authors:Ma, X, Bazan, J.F, Starovasnik, M.A.
Deposit date:2012-02-03
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKC
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Crystal Structure of Human Interleukin-34
Descriptor: Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ma, X, Bazan, J.F, Starovasnik, M.A.
Deposit date:2012-02-03
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
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221051

數據於2024-06-12公開中

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