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4MSA
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Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole)
Descriptor: 5-nitro-1H-benzimidazole, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Authors:Sridar, V, Badger, J, Logan, C, Chie-Leon, B, Nienaber, V.
Deposit date:2013-09-18
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
J Biomol Screen, 19, 2014

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