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PDB: 24 件

1MHN
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High resolution crystal structure of the SMN Tudor domain
分子名称: Survival motor neuron protein
著者Sprangers, R, Groves, M.R, Sinning, I, Sattler, M.
登録日2002-08-20
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High Resolution X-ray and NMR Structures of the SMN Tudor Domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
J.Mol.Biol., 327, 2003
1K1G
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STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1
分子名称: 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3', SF1-Bo isoform
著者Liu, Z, Luyten, I, Bottomley, M.J, Messias, A.C, Houngninou-Molango, S, Sprangers, R, Zanier, K, Kramer, A, Sattler, M.
登録日2001-09-25
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of the intron branch site RNA by splicing factor 1.
Science, 294, 2001
8R1O
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Structure of C. thermophilum RNA exosome core
分子名称: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ...
著者Lazzaretti, D, Liebau, J, Pilsl, M, Sprangers, R.
登録日2023-11-02
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex
Biorxiv, 2024
7PVM
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NMR structure of the C. thermophilum Xrn2 zinc finger
分子名称: 5'-3' exoribonuclease, ZINC ION
著者Overbeck, J.H, Sprangers, R, Wurm, J.P.
登録日2021-10-05
公開日2022-07-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Observation of conformational changes that underlie the catalytic cycle of Xrn2.
Nat.Chem.Biol., 18, 2022
7OPK
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Crystal structure of C. thermophilum Xrn2
分子名称: 5'-3' exoribonuclease, MAGNESIUM ION
著者Overbeck, J.H, Sprangers, R.
登録日2021-06-01
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Observation of conformational changes that underlie the catalytic cycle of Xrn2.
Nat.Chem.Biol., 18, 2022
1Y7O
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The structure of Streptococcus pneumoniae A153P ClpP
分子名称: ATP-dependent Clp protease proteolytic subunit, CALCIUM ION
著者Kimber, M.S, Gribun, A, Ching, R, Sprangers, R, Fiebig, K.M, Houry, W.A.
登録日2004-12-09
公開日2005-02-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation.
J.Biol.Chem., 280, 2005
8PEL
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Structure of C. thermophilum RNA exosome core
分子名称: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ...
著者Lazzaretti, D, Holdermann, I, Sprangers, R.
登録日2023-06-14
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.81 Å)
主引用文献Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex
Biorxiv, 2024
8PNK
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Crystal structure of the Ded1p RecA1 domain
分子名称: ATP-dependent RNA helicase DED1
著者Huebner, J, Sprangers, R.
登録日2023-06-30
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the Ded1p RecA1 domain
To Be Published
5JP4
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Crystal structure of S. pombe Dcp1 in complex with the decapping enhancer EDC
分子名称: Uncharacterized protein C18G6.09c, mRNA-decapping enzyme subunit 1
著者Wurm, J.P, Sprangers, R.
登録日2016-05-03
公開日2016-06-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.043 Å)
主引用文献The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface.
Rna, 22, 2016
7BBB
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Solution structure of C-terminal RecA and RRM domains of the DEAD box helicase DbpA
分子名称: ATP-dependent RNA helicase DbpA
著者Wurm, J.P, Sprangers, R.
登録日2020-12-17
公開日2021-07-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome.
Proc.Natl.Acad.Sci.USA, 118, 2021
6TRQ
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S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, L-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHONATE, ...
著者Fuchs, A.-L, Neu, A, Sprangers, R.
登録日2019-12-19
公開日2020-07-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.944 Å)
主引用文献Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
6GBS
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Crystal Structure of the C. themophilum Scavenger Decapping Enzyme DcpS apo form
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Putative mRNA decapping protein
著者Fuchs, A.-L, Neu, A, Sprangers, R.
登録日2018-04-16
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
5BV3
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Yeast Scavenger Decapping Enzyme in complex with m7GDP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION, SULFATE ION, ...
著者Neu, A, Neu, U, Sprangers, R.
登録日2015-06-04
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献An excess of catalytically required motions inhibits the scavenger decapping enzyme.
Nat.Chem.Biol., 11, 2015
1QMC
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C-terminal DNA-binding domain of HIV-1 integrase, NMR, 42 structures
分子名称: HIV-1 INTEGRASE
著者Eijkelenboom, A.P.A.M, Sprangers, R, Hard, K, Puras Lutzke, R.A, Plasterk, R.H.A, Boelens, R, Kaptein, R.
登録日1999-09-27
公開日1999-12-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Refined Solution Structure of the C-Terminal DNA-Binding Domain of Human Immunovirus-1 Integrase.
Proteins: Struct.,Funct., Genet., 36, 1999
1G5V
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SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN
分子名称: SURVIVAL MOTOR NEURON PROTEIN 1
著者Selenko, P, Sprangers, R, Stier, G, Buehler, D, Fischer, U, Sattler, M.
登録日2000-11-02
公開日2001-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献SMN tudor domain structure and its interaction with the Sm proteins.
Nat.Struct.Biol., 8, 2001
4Q2S
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Crystal Structure of S. pombe Pdc1 Ge1 Domain
分子名称: PDC1 GE1 DOMAIN
著者Noeldeke, E.R, Neu, A, Zocher, G, Sprangers, R.
登録日2014-04-09
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献In vitro reconstitution of a cellular phase-transition process that involves the mRNA decapping machinery.
Angew.Chem.Int.Ed.Engl., 53, 2014
3SWN
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BU of 3swn by Molmil
Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings
分子名称: U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, ...
著者Mund, M, Neu, A, Ullmann, J.L, Neu, U, Sprangers, R.
登録日2011-07-14
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings.
J.Mol.Biol., 414, 2011
5N2V
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Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Edc1, MAGNESIUM ION, ...
著者Holdermann, I, Sprangers, R.
登録日2017-02-08
公開日2017-05-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1O0P
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Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
分子名称: Splicing Factor SF1, Splicing factor U2AF 65 kDa subunit
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-02-24
公開日2003-05-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
4A54
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Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3, MRNA DECAPPING COMPLEX SUBUNIT 2
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
4A53
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Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
1OPI
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SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE
分子名称: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-03-05
公開日2004-03-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
2KU1
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Dynamic Regulation of Archaeal Proteasome Gate Opening as Studied by TROSY-NMR
分子名称: Proteasome subunit alpha
著者Religa, T.L, Sprangers, R, Kay, L.E.
登録日2010-02-11
公開日2010-04-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMR.
Science, 328, 2010
2KU2
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Dynamic Regulation of Archaeal Proteasome Gate Opening as Studied by TROSY-NMR
分子名称: Proteasome subunit alpha
著者Religa, T.L, Sprangers, R, Kay, L.E.
登録日2010-02-11
公開日2010-04-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMR.
Science, 328, 2010

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