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PDB: 36 件
8T0J
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Salmonella Typhimurium ArnD
分子名称: Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
著者Sousa, M.C, Munoz-Escudero, D, Lee, M.
登録日2023-06-01
公開日2023-10-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.
Biochemistry, 62, 2023
1BUP
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T13S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Sousa, M.C, Mckay, D.B.
登録日1998-09-03
公開日1998-09-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
8FTN
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E. coli ArnA dehydrogenase domain mutant - N492A
分子名称: Bifunctional UDP-4-amino-4-deoxy-L-arabinose formyltransferase/UDP-glucuronic acid oxidase ArnA, SULFATE ION
著者Sousa, M.C, Mitchell, M.E.
登録日2023-01-12
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry, 62, 2023
8GJH
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Salmonella ArnA
分子名称: Bifunctional polymyxin resistance protein ArnA, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
著者Sousa, M.C, Mitchell, M.E, Gatzeva-Topalova, P.Z.
登録日2023-03-15
公開日2023-08-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry, 62, 2023
1KYI
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HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex
分子名称: 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ...
著者Sousa, M.C, Kessler, B.M, Overkleeft, H.S, McKay, D.B.
登録日2002-02-04
公開日2002-05-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor: Corroboration of a Proposed Mechanism of Allosteric Activation of HslV by HslU
J.Mol.Biol., 318, 2002
4LDR
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Structure of the S283Y mutant of MRDI
分子名称: Methylthioribose-1-phosphate isomerase
著者Sousa, M.C, Templeton, P.D, Metzner, S.I.
登録日2013-06-25
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion.
Biochemistry, 52, 2013
4LDQ
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Crystal Structure of the Mediator of Rho Dependent Invasion
分子名称: Methylthioribose-1-phosphate isomerase
著者Sousa, M.C, Templeton, P.D, Metzner, S.I.
登録日2013-06-24
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion.
Biochemistry, 52, 2013
2BUP
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BU of 2bup by Molmil
T13G Mutant of the ATPASE fragment of Bovine HSC70
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Sousa, M.C, Mckay, D.B.
登録日1998-09-08
公開日1998-09-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
1G3I
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CRYSTAL STRUCTURE OF THE HSLUV PROTEASE-CHAPERONE COMPLEX
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT HSLU PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV
著者Sousa, M.C, Trame, C.B, Tsuruta, H, Wilbanks, S.M, Reddy, V.S, McKay, D.B.
登録日2000-10-24
公開日2000-11-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Crystal and solution structures of an HslUV protease-chaperone complex.
Cell(Cambridge,Mass.), 103, 2000
1G3K
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CRYSTAL STRUCTURE OF THE H. INFLUENZAE PROTEASE HSLV AT 1.9 A RESOLUTION
分子名称: ATP-DEPENDENT PROTEASE HSLV, SODIUM ION
著者Sousa, M.C, McKay, D.B.
登録日2000-10-24
公開日2000-11-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal and solution structures of an HslUV protease-chaperone complex.
Cell(Cambridge,Mass.), 103, 2000
1JJW
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Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution
分子名称: ATP-DEPENDENT PROTEASE HSLV, POTASSIUM ION
著者Sousa, M.C, McKay, D.B.
登録日2001-07-09
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site.
Acta Crystallogr.,Sect.D, 57, 2001
1JMV
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Structure of Haemophylus influenzae Universal Stress Protein At 1.85A Resolution
分子名称: SULFATE ION, Universal Stress Protein A
著者Sousa, M.C, McKay, D.B.
登録日2001-07-20
公開日2001-12-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the universal stress protein of Haemophilus influenzae.
Structure, 9, 2001
4OCA
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BU of 4oca by Molmil
Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N
分子名称: (2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr an-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase
著者Sousa, M.C, Lee, M.
登録日2014-01-08
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria.
Biochemistry, 53, 2014
4Q3J
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BU of 4q3j by Molmil
Crystal structure of NFkB-p65-degrading zinc protease family protein
分子名称: MAGNESIUM ION, NFkB-p65-degrading zinc protease family protein, ZINC ION
著者Sousa, M.C, Turco, M.M.
登録日2014-04-11
公開日2014-07-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.862 Å)
主引用文献The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition.
Biochemistry, 53, 2014
1U2M
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BU of 1u2m by Molmil
Crystal Structure of Skp
分子名称: Histone-like protein HLP-1
著者Walton, T.A, Sousa, M.C.
登録日2004-07-19
公開日2004-08-24
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Skp, a Prefoldin-like Chaperone that Protects Soluble and Membrane Proteins from Aggregation
Mol.Cell, 15, 2004
1U9J
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Crystal Structure of E. coli ArnA (PmrI) Decarboxylase Domain
分子名称: Hypothetical protein yfbG, SULFATE ION
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2004-08-09
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Escherichia coli ArnA (PmrI) Decarboxylase Domain. A Key Enzyme for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance
Biochemistry, 43, 2004
1YRW
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Crystal Structure of E.coli ArnA Transformylase Domain
分子名称: protein ArnA
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2005-02-04
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.
Biochemistry, 44, 2005
3EFC
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BU of 3efc by Molmil
Crystal Structure of YaeT periplasmic domain
分子名称: Outer membrane protein assembly factor yaeT
著者Gatzeva-Topalova, P.Z, Walton, T.A, Sousa, M.C.
登録日2008-09-08
公開日2008-12-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of YaeT: conformational flexibility and substrate recognition.
Structure, 16, 2008
4HDJ
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Crystal Structure of BamB from Pseudomonas aeruginosa
分子名称: Outer membrane protein assembly factor BamB
著者Jansen, K.B, Baker, S.L, Sousa, M.C.
登録日2012-10-02
公開日2013-04-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of BamB from Pseudomonas aeruginosa and functional evaluation of its conserved structural features.
Plos One, 7, 2012
3OG5
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Crystal Structure of BamA POTRA45 tandem
分子名称: Outer membrane protein assembly complex, YaeT protein
著者Gatzeva-Topalova, P.Z, Warner, L.R, Pardi, A, Sousa, M.C.
登録日2010-08-16
公開日2010-11-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structure and Flexibility of the Complete Periplasmic Domain of BamA: The Protein Insertion Machine of the Outer Membrane
Structure, 18, 2010
3QKY
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Crystal structure of Rhodothermus marinus BamD
分子名称: Outer membrane assembly lipoprotein YfiO
著者Sandoval, C.M, Baker, S.L, Jansen, K, Metzner, S.I, Sousa, M.C.
登録日2011-02-02
公開日2011-04-20
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of BamD: an essential component of the beta-Barrel assembly machinery of gram-negative bacteria.
J.Mol.Biol., 409, 2011
4PK1
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Structure of BamB fused to a BamA POTRA domain fragment
分子名称: Chimera protein of Outer membrane protein assembly factors BamA and BamB
著者Jansen, K.B, Sousa, M.C.
登録日2014-05-13
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of BamB Bound to a Periplasmic Domain Fragment of BamA, the Central Component of the beta-Barrel Assembly Machine.
J.Biol.Chem., 290, 2015
1Z73
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Crystal Structure of E. coli ArnA dehydrogenase (decarboxylase) domain, S433A mutant
分子名称: GLYCEROL, SULFATE ION, protein ArnA
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2005-03-24
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
1Z7B
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Crystal structure of E.coli ArnA dehydrogenase (decarboxylase) domain, R619E mutant
分子名称: SULFATE ION, protein ArnA
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2005-03-24
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
1Z7E
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Crystal structure of full length ArnA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID, protein ArnA
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2005-03-24
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005

 

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