4LDR

Structure of the S283Y mutant of MRDI

Summary for 4LDR

Entry DOI	10.2210/pdb4ldr/pdb
Related	4LDQ
Descriptor	Methylthioribose-1-phosphate isomerase (2 entities in total)
Functional Keywords	helix bundle, rossmann-like fold, isomerase, cell invasion
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9BV20
Total number of polymer chains	2
Total formula weight	78541.57
Authors	Sousa, M.C.,Templeton, P.D.,Metzner, S.I. (deposition date: 2013-06-25, release date: 2013-07-31, Last modification date: 2024-02-28)
Primary citation	Templeton, P.D.,Litman, E.S.,Metzner, S.I.,Ahn, N.G.,Sousa, M.C. Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion. Biochemistry, 52:5675-5684, 2013 Cited by PubMed: 23859498 DOI: 10.1021/bi400556e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.292 Å)

Structure validation