8V7Q
 
 | |
1LO6
 | | Human Kallikrein 6 (hK6) active form with benzamidine inhibitor at 1.56 A resolution | | 分子名称: | BENZAMIDINE, Kallikrein 6, MAGNESIUM ION | | 著者 | Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Dhanarajan, P, Thompson, S.M, Blaber, M. | | 登録日 | 2002-05-06 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Crystal structure and biochemical characterization of human kallikrein 6 reveals a
trypsin-like kallikrein is expressed in the central nervous system
To be Published
|
|
1S9O
 | | Solution structure of the nitrous acid induced DNA interstrand cross-linked dodecamer duplex CGCTAC(G)TAGCG with the cross-linked guanines denoted (G) | | 分子名称: | 5'-D(*CP*GP*CP*TP*AP*CP*GP*TP*AP*GP*CP*G)-3' | | 著者 | Edfeldt, N.B, Harwood, E.A, Sigurdsson, S.T, Hopkins, P.B, Reid, B.R. | | 登録日 | 2004-02-05 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a nitrous acid induced DNA interstrand cross-link.
Nucleic Acids Res., 32, 2004
|
|
5EQ4
 | | Crystal structure of the SrpA adhesin R347E mutant from Streptococcus sanguinis | | 分子名称: | ACETATE ION, CALCIUM ION, Platelet-binding glycoprotein | | 著者 | Loukachevitch, L.V, McCulloch, K.M, Vann, K.R, Wawrzak, Z, Anderson, S, Iverson, T.M. | | 登録日 | 2015-11-12 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J.Biol.Chem., 291, 2016
|
|
3EYO
 | | Crystal structure of anti-human cytomegalovirus antibody 8F9 | | 分子名称: | 8f9 Fab, AD-2 | | 著者 | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | | 登録日 | 2008-10-21 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.
Embo J., 27, 2008
|
|
6T26
 | | X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine | | 分子名称: | Alkaline phosphatase, CHLORIDE ION, CYCLOHEXYLAMMONIUM ION, ... | | 著者 | Asgeirsson, B, Hjorleifsson, J.G, Markusson, S, Helland, R. | | 登録日 | 2019-10-07 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.265 Å) | | 主引用文献 | X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine.
Biochem Biophys Rep, 24, 2020
|
|
3F12
 | | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus | | 分子名称: | 8f9 Fab, M2J1 Fab | | 著者 | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | | 登録日 | 2008-10-27 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.
Embo J., 27, 2008
|
|
6DVU
 | |
1O9W
 | | F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17A-G FIMBRIAL ADHESIN | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
|
|
4B05
 | | Preclinical characterization of AZD3839, a novel clinical candidate BACE1 inhibitor for the treatment of Alzheimer Disease | | 分子名称: | (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-(3-pyrimidin-5-ylphenyl)-1H-isoindol-3-amine, ACETATE ION, BETA-SECRETASE 1, ... | | 著者 | Jeppsson, F, Eketjall, S, Janson, J, Karlstrom, S, Gustavsson, S, Olsson, L.L, Radesater, A.C, Ploeger, B, Cebers, G, Kolmodin, K, Swahn, B.M, von Berg, S, Bueters, T, Falting, J. | | 登録日 | 2012-06-28 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease.
J. Biol. Chem., 287, 2012
|
|
1BY8
 | | THE CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN K | | 分子名称: | PROTEIN (PROCATHEPSIN K) | | 著者 | Lalonde, J.M, Zhao, B, Smith, W.W, Janson, C.A, Desjarlais, R.L, Tomaszek, T.A, Carr, T.J, Thompson, S.K, Yamashita, D.S, Veber, D.F, Abdel-Mequid, S.S. | | 登録日 | 1998-10-27 | | 公開日 | 1999-10-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of human procathepsin K.
Biochemistry, 38, 1999
|
|
1A1R
 | | HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX | | 分子名称: | NS3 PROTEIN, NS4A PROTEIN, ZINC ION | | 著者 | Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A. | | 登録日 | 1997-12-15 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
Cell(Cambridge,Mass.), 87, 1996
|
|
3IRD
 | |
1FW5
 | | SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1 | | 分子名称: | NONSTRUCTURAL PROTEIN NSP1 | | 著者 | Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L. | | 登録日 | 2000-09-21 | | 公開日 | 2001-09-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane binding mechanism of an RNA virus-capping enzyme.
J.Biol.Chem., 275, 2001
|
|
2WOA
 | | MMP12 complex with a beta hydroxy carboxylic acid | | 分子名称: | (3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC ACID, CALCIUM ION, GLYCEROL, ... | | 著者 | Holmes, I.P, Gaines, S, Watson, S.P, Lorthioir, O, Walker, A, Baddeley, S.J, Herbert, S, Egan, D, Convery, M.A, Singh, O.M.P, Gross, J.W, Strelow, J.M, Smith, R.H, Amour, A.J, Brown, D, Martin, S.L. | | 登録日 | 2009-07-22 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
2WO8
 | | MMP12 complex with a beta hydroxy carboxylic acid | | 分子名称: | (3S)-5-biphenyl-4-yl-3-hydroxypentanoic acid, CALCIUM ION, GLYCEROL, ... | | 著者 | Holmes, I.P, Gaines, S, Watson, S.P, Lorthioir, O, Walker, A, Baddeley, S.J, Herbert, S, Egan, D, Convery, M.A, Singh, O.M.P, Gross, J.W, Strelow, J.M, Smith, R.H, Amour, A.J, Brown, D, Martin, S.L. | | 登録日 | 2009-07-22 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
3ZX8
 | | Cryo-EM reconstruction of native and expanded Turnip Crinkle virus | | 分子名称: | CAPSID PROTEIN | | 著者 | Bakker, S.E, Robottom, J, Hogle, J.M, Maeda, A, Pearson, A.R, Stockley, P.G, Ranson, N.A, Harrison, S.C. | | 登録日 | 2011-08-08 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | | 主引用文献 | Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus.
J.Mol.Biol., 417, 2012
|
|
1O9Z
 | | F17-aG lectin domain from Escherichia coli (ligand free) | | 分子名称: | F17-AG LECTIN DOMAIN | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-23 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
|
|
1O8T
 | | Global Structure and Dynamics of Human Apolipoprotein CII in Complex with Micelles: Evidence for increased mobility of the helix involved in the activation of lipoprotein lipase | | 分子名称: | APOLIPOPROTEIN C-II | | 著者 | Zdunek, J, Martinez, G.V, Schleucher, J, Lycksell, P.O, Yin, Y, Nilsson, S, Shen, Y, Olivecrona, G, Wijmenga, S. | | 登録日 | 2002-11-29 | | 公開日 | 2003-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Global Structure and Dynamics of Human Apolipoprotein Cii in Complex with Micelles: Evidence for Increased Mobility of the Helix Involved in the Activation of Lipoprotein Lipase
Biochemistry, 42, 2003
|
|
1C01
 | | SOLUTION STRUCTURE OF MIAMP1, A PLANT ANTIMICROBIAL PROTEIN | | 分子名称: | ANTIMICROBIAL PEPTIDE 1 | | 著者 | McManus, A.M, Nielsen, K.J, Marcus, J.P, Harrison, S.J, Green, J.L, Manners, J.M, Craik, D.J. | | 登録日 | 1999-07-13 | | 公開日 | 2000-07-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | MiAMP1, a novel protein from Macadamia integrifolia adopts a Greek key beta-barrel fold unique amongst plant antimicrobial proteins.
J.Mol.Biol., 293, 1999
|
|
1OKE
 | |
1J90
 | | Crystal Structure of Drosophila Deoxyribonucleoside Kinase | | 分子名称: | 2'-DEOXYCYTIDINE, Deoxyribonucleoside kinase, SULFATE ION | | 著者 | Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H. | | 登録日 | 2001-05-23 | | 公開日 | 2001-11-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
|
|
1O9V
 | | F17-aG lectin domain from Escherichia coli in complex with a selenium carbohydrate derivative | | 分子名称: | F17-AG LECTIN DOMAIN, methyl 2-acetamido-2-deoxy-1-seleno-beta-D-glucopyranoside | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
|
|
2RAI
 | | The PX-BAR membrane remodeling unit of Sorting Nexin 9 | | 分子名称: | Sorting nexin-9 | | 著者 | Pylypenko, O, Lundmark, R, Rasmuson, E, Carlsson, S.R, Rak, A. | | 登録日 | 2007-09-16 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The PX-BAR membrane-remodeling unit of sorting nexin 9
Embo J., 26, 2007
|
|
1TFP
 | | TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN) | | 分子名称: | SULFATE ION, TRANSTHYRETIN | | 著者 | Sunde, M, Richardson, S.J, Chang, L, Pettersson, T.M, Schreiber, G, Blake, C.C.F. | | 登録日 | 1996-01-05 | | 公開日 | 1996-06-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of transthyretin from chicken.
Eur.J.Biochem., 236, 1996
|
|
