7LZ2
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with methionine | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZH
| Structure of the glutamate receptor-like channel AtGLR3.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ1
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with serine | Descriptor: | GLYCEROL, Glutamate receptor 3.4, SERINE, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ0
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with glutamate | Descriptor: | CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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5WEL
| GluA2 bound to antagonist ZK and GSG1L in digitonin, state 2 | Descriptor: | Chimera of Glutamate receptor 2, Germ cell-specific gene 1-like protein, Digitonin, ... | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-07-10 | Release date: | 2017-08-02 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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5VHX
| GluA2-1xGSG1L bound to ZK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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5WO7
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5WO6
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5WEN
| GluA2 bound to GSG1L in digitonin, state 2 | Descriptor: | Digitonin, Glutamate receptor 2,Germ cell-specific gene 1-like protein | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-07-10 | Release date: | 2017-08-02 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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7MIO
| Mouse TRPV3 in cNW11 nanodiscs, open state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIJ
| Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 4 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (1.98 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIK
| Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIL
| Mouse TRPV3 in MSP2N2 nanodiscs, sensitized state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIN
| Mouse TRPV3 in cNW11 nanodiscs, closed state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIM
| Mouse TRPV3 in cNW11 nanodiscs, closed state at 4 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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5WO8
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5WEK
| GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1 | Descriptor: | Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-07-10 | Release date: | 2017-08-02 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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5WO9
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5VHZ
| GluA2-2xGSG1L bound to L-Quisqualate | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2,Germ cell-specific gene 1-like protein | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2017-11-08 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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7LQY
| Structure of squirrel TRPV1 in apo state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol, CHLORIDE ION, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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7LR0
| Structure of squirrel TRPV1 in complex with capsaicin | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, Osm-9-like TRP channel 1, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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7LQZ
| Structure of squirrel TRPV1 in complex with RTX | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Osm-9-like TRP channel 1, SODIUM ION, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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5VHW
| GluA2-0xGSG1L bound to ZK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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5VHY
| GluA2-2xGSG1L bound to ZK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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5WEM
| GluA2 bound to GSG1L in digitonin, state 1 | Descriptor: | Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-07-10 | Release date: | 2017-08-02 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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