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PDB: 220 件

3BQ5
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Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic)
分子名称: 1,2-ETHANEDIOL, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase, ...
著者Pejchal, R, Smith, J.L, Ludwig, M.L.
登録日2007-12-19
公開日2008-03-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BOF
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Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ and Homocysteine
分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydrofolate S-homocysteine methyltransferase, POTASSIUM ION, ...
著者Koutmos, M, Smith, J.L, Ludwig, M.L.
登録日2007-12-17
公開日2008-03-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3QMW
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RedJ with PEG molecule bound in the active site
分子名称: TETRAETHYLENE GLYCOL, Thioesterase
著者Whicher, J.R, Smith, J.L.
登録日2011-02-05
公開日2011-05-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor.
J.Biol.Chem., 286, 2011
3SC0
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BU of 3sc0 by Molmil
Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin
分子名称: CO-METHYLCOBALAMIN, Methylmalonic aciduria and homocystinuria type C protein
著者Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R.
登録日2011-06-06
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
3SBZ
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Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme
分子名称: GLYCEROL, MALONATE ION, Methylmalonic aciduria and homocystinuria type C protein
著者Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R.
登録日2011-06-06
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
3SSO
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MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg and SAH, Crystal form 2
分子名称: MAGNESIUM ION, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
3SSN
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MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg, SAH, and Mycinamycin VI
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, MAGNESIUM ION, ...
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.392 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
3SSM
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MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg and SAH, Crystal form 1
分子名称: MAGNESIUM ION, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
3SBY
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Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme
分子名称: Methylmalonic aciduria and homocystinuria type C protein
著者Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R.
登録日2011-06-06
公開日2011-06-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
3QMV
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RedJ-Thioesterase from the Prodiginine biosynthetic pathway in Streptomyces coelicolor
分子名称: Thioesterase
著者Whicher, J.R, Smith, J.L.
登録日2011-02-05
公開日2011-05-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor.
J.Biol.Chem., 286, 2011
3U1T
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Haloalkane Dehalogenase, DmmA, of marine microbial origin
分子名称: CHLORIDE ION, DmmA Haloalkane Dehalogenase, MALONATE ION
著者Gehret, J.J, Smith, J.L.
登録日2011-09-30
公開日2011-12-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and activity of DmmA, a marine haloalkane dehalogenase.
Protein Sci., 21, 2012
3LCR
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BU of 3lcr by Molmil
Thioesterase from Tautomycetin Biosynthhetic Pathway
分子名称: DIMETHYL SULFOXIDE, FORMIC ACID, Tautomycetin biosynthetic PKS
著者Akey, D.L, Scaglione, J.B, Smith, J.L, Sherman, D.H.
登録日2010-01-11
公開日2010-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.
Angew.Chem.Int.Ed.Engl., 49, 2010
3LYF
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BU of 3lyf by Molmil
Crystal Structure of the Rift Valley Fever Virus Nucleocapsid Protein
分子名称: GLYCEROL, Nucleocapsid protein
著者Raymond, D.D, Smith, J.L.
登録日2010-02-26
公開日2010-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NNL
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Halogenase domain from CurA module (crystal form III)
分子名称: 2-OXOGLUTARIC ACID, CHLORIDE ION, CurA, ...
著者Khare, D, Smith, J.L.
登録日2010-06-23
公開日2010-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.883 Å)
主引用文献Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3NNF
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Halogenase domain from CurA module with Fe, chloride, and alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, CHLORIDE ION, CurA, ...
著者Khare, D, Smith, J.L.
登録日2010-06-23
公開日2010-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3NNM
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Halogenase domain from CurA module (crystal form IV)
分子名称: CurA, FORMIC ACID
著者Khare, D, Smith, J.L.
登録日2010-06-23
公開日2010-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3NNJ
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Halogenase domain from CurA module (apo Hal)
分子名称: CurA
著者Khare, D, Smith, J.L.
登録日2010-06-23
公開日2010-07-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3PC4
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BU of 3pc4 by Molmil
Full length structure of cystathionine beta-synthase from Drosophila in complex with serine
分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, CG1753, isoform A, ...
著者Koutmos, M, Smith, J.L.
登録日2010-10-21
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PC2
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Full length structure of cystathionine beta-synthase from Drosophila
分子名称: CG1753, isoform A, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Koutmos, M, Smith, J.L.
登録日2010-10-21
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PC3
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Full length structure of cystathionine beta-synthase from Drosophila in complex with aminoacrylate
分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CG1753, isoform A, ...
著者Koutmos, M, Smith, J.L.
登録日2010-10-21
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
2IGB
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BU of 2igb by Molmil
Crystal Structure of PyrR, The Regulator Of The Pyrimidine Biosynthetic Operon In Bacillus caldolyticus, UMP-bound form
分子名称: 1,2-ETHANEDIOL, PyrR bifunctional protein, URIDINE-5'-MONOPHOSPHATE
著者Chander, P, Switzer, R.L, Smith, J.L.
登録日2006-09-22
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献PyrR, the regulator of the pyrimidine biosynthetic operon in Bacillus caldolyticus
To be Published
2HFJ
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Pikromycin thioesterase with covalent pentaketide affinity label
分子名称: DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ...
著者Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L.
登録日2006-06-24
公開日2006-09-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for Macrolactonization by the Pikromycin Thioesterase
NAT.CHEM.BIOL., 2, 2006
2HFK
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Pikromycin thioesterase in complex with product 10-deoxymethynolide
分子名称: (3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L.
登録日2006-06-24
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for Macrolactonization by the Pikromycin Thioesterase
NAT.CHEM.BIOL., 2, 2006
2Q34
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Crystal Structure of the ECH2 decarboxylase domain of CurF from Lyngbya majuscula, rhombohedral crystal form
分子名称: CurF
著者Geders, T.W, Mowers, J.C, Smith, J.L.
登録日2007-05-29
公開日2007-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.
J.Biol.Chem., 282, 2007
2Q35
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Crystal Structure of the Y82F variant of ECH2 decarboxylase domain of CurF from Lyngbya majuscula
分子名称: CHLORIDE ION, CurF, GLYCEROL
著者Geders, T.W, Mowers, J.C, Smith, J.L.
登録日2007-05-29
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.
J.Biol.Chem., 282, 2007

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件を2024-08-21に公開中

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