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PDB: 27 results

8B54
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BU of 8b54 by Molmil
CDK2/cyclin A2 in complex with pyrazolo[4,3-d]pyrimidine inhibitor LGR6768
Descriptor: 1,2-ETHANEDIOL, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Djukic, S, Skerlova, J, Rezacova, P.
Deposit date:2022-09-21
Release date:2023-03-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7.
Biomed Pharmacother, 161, 2023
7B7S
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BU of 7b7s by Molmil
CDK2/cyclin A2 in complex with 3H-pyrazolo[4,3-f]quinoline-based derivative HSD1368
Descriptor: 7-(3-(trifluoromethyl)-1H-pyrazol-4yl)-3,8,10,11-tetrahydropyrazolo[4,3-f]thiopyrano[3,4-c]quinoline 9-oxide, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Djukic, S, Skerlova, J, Rezacova, P.
Deposit date:2020-12-11
Release date:2021-08-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:3 H -Pyrazolo[4,3- f ]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
J.Med.Chem., 64, 2021
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數據於2024-11-13公開中

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