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PDB: 164 件

4PLJ
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Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-15
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
4PLK
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Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-08
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
4U02
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Crystal structure of apo-TTHA1159
分子名称: Amino acid ABC transporter, ATP-binding protein, SULFATE ION
著者Karthiga Devi, S, Chichili, V.P.R, Velmurugan, D, Sivaraman, J.
登録日2014-07-11
公開日2015-05-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural basis for the hydrolysis of ATP by a nucleotide binding subunit of an amino acid ABC transporter from Thermus thermophilus
J.Struct.Biol., 190, 2015
4U00
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Crystal structure of TTHA1159 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Amino acid ABC transporter, ATP-binding protein, ...
著者Karthiga Devi, S, Chichili, V.P.R, Velmurugan, D, Sivaraman, J.
登録日2014-07-11
公開日2015-05-13
最終更新日2021-09-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the hydrolysis of ATP by a nucleotide binding subunit of an amino acid ABC transporter from Thermus thermophilus
J.Struct.Biol., 190, 2015
3RKD
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Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody
分子名称: Capsid protein, Monoclonal Antibody, Heavy Chain, ...
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
3RJ2
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Structural and functional characterization of a novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus (SGIV)
分子名称: Putative uncharacterized protein
著者Chen, L, Liu, Y, Sivaraman, J, Hew, C.L.
登録日2011-04-15
公開日2012-02-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus
J.Virol., 85, 2011
3RKC
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Hepatitis E Virus Capsid Protein E2s Domain (genotype IV)
分子名称: Capsid protein
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
1KAR
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR)
分子名称: HISTAMINE, Histidinol dehydrogenase, ZINC ION
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M.
登録日2001-11-02
公開日2002-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KAE
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR)
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Histidinol dehydrogenase, ...
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M.
登録日2001-11-01
公開日2002-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KAH
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L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR)
分子名称: HISTIDINE, Histidinol dehydrogenase, ZINC ION
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M.
登録日2001-11-02
公開日2002-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
3VP0
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Crystal structure of human glutaminase in complex with L-glutamine
分子名称: GLUTAMINE, Glutaminase kidney isoform, mitochondrial, ...
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP2
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Crystal structure of human glutaminase in complex with inhibitor 2
分子名称: 5,5'-(sulfanediyldiethane-2,1-diyl)bis(1,3,4-thiadiazol-2-amine), Glutaminase kidney isoform, mitochondrial, ...
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
1LKZ
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Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli.
分子名称: Ribose 5-phosphate isomerase A
著者Rangarajan, E.S, Sivaraman, J, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2002-04-26
公開日2002-05-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli
Proteins, 48, 2002
3VOZ
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Crystal structure of human glutaminase in complex with BPTES
分子名称: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide), ...
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VOY
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Crystal structure of human glutaminase in apo form
分子名称: Glutaminase kidney isoform, mitochondrial, SULFATE ION
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP3
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Crystal structure of human glutaminase in complex with inhibitor 3
分子名称: 5,5'-pentane-1,5-diylbis(1,3,4-thiadiazol-2-amine), Glutaminase kidney isoform, mitochondrial, ...
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP4
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Crystal structure of human glutaminase in complex with inhibitor 4
分子名称: 5,5'-butane-1,4-diylbis(1,3,4-thiadiazol-2-amine), Glutaminase kidney isoform, mitochondrial
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VTS
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BU of 3vts by Molmil
Crystal structure of a three finger toxin from snake venom
分子名称: Cytotoxin 1
著者Jobichen, C, Sivaraman, J.
登録日2012-06-06
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Identification and structural characterization of a new three-finger toxin hemachatoxin from Hemachatus haemachatus venom.
Plos One, 7, 2012
3VP1
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Crystal structure of human glutaminase in complex with L-glutamate and BPTES
分子名称: GLUTAMIC ACID, Glutaminase kidney isoform, mitochondrial, ...
著者Thangavelu, K, Sivaraman, J.
登録日2012-02-23
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
1NQC
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BU of 1nqc by Molmil
Crystal structures of Cathepsin S inhibitor complexes
分子名称: Cathepsin S, N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE
著者Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Menard, R, Cygler, M, Rath, V.L.
登録日2003-01-21
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
1NPZ
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Crystal structures of Cathepsin S inhibitor complexes
分子名称: Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide
著者Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L.
登録日2003-01-20
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
4N7D
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Selenomethionine incorporated Bla g 4
分子名称: Bla g 4 allergen variant 1, CITRIC ACID, GLYCEROL
著者Offermann, L.R, Chan, S.L, Osinski, T, Tan, Y.W, Chew, F.T, Sivaraman, J, Mok, Y.K, Minor, W, Chruszcz, M.
登録日2013-10-15
公開日2014-05-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The major cockroach allergen Bla g 4 binds tyramine and octopamine.
Mol.Immunol., 60, 2014
4O7D
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Crystal structure of human glutaminase in complex DON
分子名称: 5-OXO-L-NORLEUCINE, Glutaminase kidney isoform, mitochondrial
著者Thangavelu, K, Sivaraman, J.
登録日2013-12-24
公開日2014-04-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)
Sci Rep, 4, 2014
4RUD
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Crystal structure of a three finger toxin
分子名称: Three-finger toxin 3b, ZINC ION
著者Jobichen, C, Sivaraman, J.
登録日2014-11-18
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
3OB1
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Crystal structure of c-Cbl TKB domain in complex with double phosphorylated Spry2 peptide
分子名称: 12-meric peptide from Protein sprouty homolog 2, E3 ubiquitin-protein ligase CBL
著者Sun, Q, Sivaraman, J.
登録日2010-08-06
公開日2010-08-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain
Plos One, 5, 2010

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