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PDB: 13 results

8BF8
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ISDra2 TnpB in complex with reRNA
Descriptor: Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D.
Deposit date:2022-10-24
Release date:2023-04-12
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8QG0
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Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 17 nt RNA guide and 17 nt DNA target
Descriptor: AfAgo-N protein, DNA target 17 nt, Piwi protein, ...
Authors:Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Zagorskaite, E, Silanskas, A.
Deposit date:2023-09-05
Release date:2024-01-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
8EX9
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ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved)
Descriptor: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
Deposit date:2022-10-25
Release date:2023-04-05
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8EXA
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BU of 8exa by Molmil
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 1 (RuvC domain resolved)
Descriptor: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
Deposit date:2022-10-25
Release date:2023-04-05
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
6F1S
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C-terminal domain of CglI restriction endonuclease H subunit
Descriptor: 1,2-ETHANEDIOL, CglIIR protein, FORMIC ACID
Authors:Tamulaitiene, G, Grigaitis, R, Zaremba, M, Silanskas, A.
Deposit date:2017-11-23
Release date:2018-02-14
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.
Nucleic Acids Res., 46, 2018
8PVV
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Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 30 nt RNA guide and 51 nt DNA target
Descriptor: Archaeoglobus fulgidus AfAgo-N protein, DNA (51-MER), MAGNESIUM ION, ...
Authors:Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Sasnauskas, G, Zagorskaite, E, Silanskas, A.
Deposit date:2023-07-18
Release date:2024-01-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
6QXF
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BU of 6qxf by Molmil
Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-07
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
6QXT
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BU of 6qxt by Molmil
Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-08
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
6QY3
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Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ...
Authors:Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B.
Deposit date:2019-03-08
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
4QDL
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BU of 4qdl by Molmil
Crystal structure of E.coli Cas1-Cas2 complex
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2
Authors:Tamulaitiene, G, Sinkunas, T, Silanskas, A, Gasiunas, G, Grazulis, S, Siksnys, V.
Deposit date:2014-05-14
Release date:2014-05-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of E.coli Cas1-Cas2 complex
To be Published
4RCT
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BU of 4rct by Molmil
Crystal structure of R-protein of NgoAVII restriction endonuclease
Descriptor: Restriction endonuclease R.NgoVII
Authors:Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V.
Deposit date:2014-09-17
Release date:2014-12-24
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
4RD5
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BU of 4rd5 by Molmil
Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA
Descriptor: DNA (5'-D(*CP*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*GP*G)-3'), Restriction endonuclease R.NgoVII
Authors:Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V.
Deposit date:2014-09-18
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
4RDM
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BU of 4rdm by Molmil
Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA
Descriptor: DNA (5'-D(*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3)', DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*G)-3)', Restriction endonuclease R.NgoVII, ...
Authors:Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V.
Deposit date:2014-09-19
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014

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PDB entries from 2024-06-12

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