1BFJ
| SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | P85 ALPHA | 著者 | Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. | 登録日 | 1997-11-18 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
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1BFI
| SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, 30 STRUCTURES | 分子名称: | P85 ALPHA | 著者 | Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. | 登録日 | 1997-11-18 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
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2R63
| STRUCTURAL ROLE OF A BURIED SALT BRIDGE IN THE 434 REPRESSOR DNA-BINDING DOMAIN, NMR, 20 STRUCTURES | 分子名称: | REPRESSOR PROTEIN FROM BACTERIOPHAGE 434 | 著者 | Pervushin, K.V, Billeter, M, Siegal, G, Wuthrich, K. | 登録日 | 1996-11-13 | 公開日 | 1997-06-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural role of a buried salt bridge in the 434 repressor DNA-binding domain. J.Mol.Biol., 264, 1996
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1MO8
| ATPase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Sodium/Potassium-Transporting ATPase alpha-1 | 著者 | Hilge, M, Siegal, G, Vuister, G.W, Guentert, P, Gloor, S.M, Abrahams, J.P. | 登録日 | 2002-09-08 | 公開日 | 2003-06-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Nat.Struct.Biol., 10, 2003
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1MO7
| ATPase | 分子名称: | Sodium/Potassium-transporting ATPase alpha-1 chain | 著者 | Hilge, M, Siegal, G, Vuister, G.W, Guentert, P, Gloor, S.M, Abrahams, J.P. | 登録日 | 2002-09-08 | 公開日 | 2003-06-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Nat.Struct.Biol., 10, 2003
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2K7F
| HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA | 分子名称: | 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1 | 著者 | Kobayashi, M, Ab, E, Bonvin, A, Siegal, G. | 登録日 | 2008-08-10 | 公開日 | 2009-09-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex. J.Biol.Chem., 285, 2010
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2K6G
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1B64
| SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES | 分子名称: | ELONGATION FACTOR 1-BETA | 著者 | Perez, J.M.J, Siegal, G, Kriek, J, Hard, K, Dijk, J, Canters, G.W, Moller, W. | 登録日 | 1999-01-20 | 公開日 | 1999-05-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the guanine nucleotide exchange domain of human elongation factor 1beta reveals a striking resemblance to that of EF-Ts from Escherichia coli. Structure Fold.Des., 7, 1999
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1QAD
| Crystal Structure of the C-Terminal SH2 Domain of the P85 alpha Regulatory Subunit of Phosphoinositide 3-Kinase: An SH2 domain mimicking its own substrate | 分子名称: | PI3-KINASE P85 ALPHA SUBUNIT | 著者 | Hoedemaeker, P.J, Siegal, G, Roe, M, Driscoll, P.C, Abrahams, J.P.A. | 登録日 | 1999-02-26 | 公開日 | 1999-10-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the C-terminal SH2 domain of the p85alpha regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate. J.Mol.Biol., 292, 1999
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1PBU
| Solution structure of the C-terminal domain of the human eEF1Bgamma subunit | 分子名称: | Elongation factor 1-gamma | 著者 | Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G. | 登録日 | 2003-05-15 | 公開日 | 2003-07-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | 1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma. J.Biomol.Nmr, 26, 2003
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1R63
| STRUCTURAL ROLE OF A BURIED SALT BRIDGE IN THE 434 REPRESSOR DNA-BINDING DOMAIN, NMR, 20 STRUCTURES | 分子名称: | REPRESSOR PROTEIN FROM BACTERIOPHAGE 434 | 著者 | Pervushin, K.V, Billeter, M, Siegal, G, Wuthrich, K. | 登録日 | 1996-11-08 | 公開日 | 1997-06-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural role of a buried salt bridge in the 434 repressor DNA-binding domain. J.Mol.Biol., 264, 1996
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2XYU
| Crystal structure of EphA4 kinase domain in complex with VUF 12058 | 分子名称: | 5-(5-FLUORO-2-METHYLPHENYL)-6,7,8,9-TETRAHYDRO-3H-PYRAZOLO[3,4-C]ISOQUINOLIN-1-AMINE, EPHRIN TYPE-A RECEPTOR 4,, GLYCEROL | 著者 | Farenc, C.J.A, Celie, P.H.N, vanLinden, O.P.J, Siegal, G. | 登録日 | 2010-11-19 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.117 Å) | 主引用文献 | Fragment Based Lead Discovery of Small Molecule Inhibitors for the Epha4 Receptor Tyrosine Kinase. Eur.J.Med.Chem., 47, 2012
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2Y6M
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2Y6O
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4KLZ
| Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis | 分子名称: | GTP-binding protein Rit1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Shah, D.M, Kobayashi, M, Keizers, P.H, Tuin, A.W, Ab, E, Manning, L, Rzepiela, A.A, Andrews, M, Hoedemaeker, F.J, Siegal, G. | 登録日 | 2013-05-07 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis To be Published
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