7YER
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![BU of 7yer by Molmil](/molmil-images/mine/7yer) | The structure of EBOV L-VP35 complex | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, ZINC ION | Authors: | Shi, Y, Yuan, B, Peng, Q. | Deposit date: | 2022-07-06 | Release date: | 2022-10-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the Ebola virus polymerase complex. Nature, 610, 2022
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7YES
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7YET
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![BU of 7yet by Molmil](/molmil-images/mine/7yet) | The structure of EBOV L-VP35 in complex with suramin | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Polymerase cofactor VP35, RNA-directed RNA polymerase L | Authors: | Shi, Y, Yuan, B, Peng, Q. | Deposit date: | 2022-07-06 | Release date: | 2022-10-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Ebola virus polymerase complex. Nature, 610, 2022
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7CBT
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![BU of 7cbt by Molmil](/molmil-images/mine/7cbt) | The crystal structure of SARS-CoV-2 main protease in complex with GC376 | Descriptor: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | Authors: | Shi, Y, Peng, G. | Deposit date: | 2020-06-13 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.346 Å) | Cite: | The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract. Emerg Microbes Infect, 10, 2021
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1YGS
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![BU of 1ygs by Molmil](/molmil-images/mine/1ygs) | CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN | Descriptor: | SMAD4 | Authors: | Shi, Y, Hata, A, Lo, R.S, Massague, J, Pavletich, N.P. | Deposit date: | 1997-10-03 | Release date: | 1998-07-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature, 388, 1997
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5Y4L
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![BU of 5y4l by Molmil](/molmil-images/mine/5y4l) | PRRSV nsp4 | Descriptor: | Non-structural protein | Authors: | Shi, Y.J, Gang, Y, Peng, G.Q. | Deposit date: | 2017-08-04 | Release date: | 2018-01-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.198 Å) | Cite: | Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus. Vet. Microbiol., 213, 2018
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3NFN
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![BU of 3nfn by Molmil](/molmil-images/mine/3nfn) | Recognition of peptide-MHC by a V-delta/V-beta TCR | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shi, Y, Qi, J, Gao, F, Gao, G.F. | Deposit date: | 2010-06-10 | Release date: | 2011-07-13 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (2.392 Å) | Cite: | Plasticity of human CD8 alpha alpha binding to peptide-HLA-A*2402 Mol.Immunol., 48, 2011
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3QZW
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![BU of 3qzw by Molmil](/molmil-images/mine/3qzw) | Plasticity of human CD8 binding to peptide-HLA-A*2402 | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2011-03-07 | Release date: | 2011-06-29 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402 Mol.Immunol., 48, 2011
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5XOV
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![BU of 5xov by Molmil](/molmil-images/mine/5xov) | Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR | Descriptor: | Beta-2-microglobulin, HIV-1 Nef138-10 peptide, HLA class I histocompatibility antigen, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-05-31 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.684 Å) | Cite: | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs. J. Virol., 91, 2017
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1DEV
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5XOT
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![BU of 5xot by Molmil](/molmil-images/mine/5xot) | Crystal structure of pHLA-B35 in complex with TU55 T cell receptor | Descriptor: | An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-05-31 | Release date: | 2017-06-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.787 Å) | Cite: | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs. J. Virol., 91, 2017
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5XOS
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![BU of 5xos by Molmil](/molmil-images/mine/5xos) | Crystal structure of HLA-B35 in complex with a pepetide antigen | Descriptor: | An HIV reverse transcriptase epitope, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-05-31 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs. J. Virol., 91, 2017
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7FIK
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![BU of 7fik by Molmil](/molmil-images/mine/7fik) | The cryo-EM structure of the CR subunit from X. laevis NPC | Descriptor: | MGC154553 protein, MGC83295 protein, MGC83926 protein, ... | Authors: | Shi, Y, Huang, G, Zhan, X. | Deposit date: | 2021-07-31 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex. Science, 376, 2022
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7FIL
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7BOM
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![BU of 7bom by Molmil](/molmil-images/mine/7bom) | Crystal structure of recombinant horse spleen apo-R52C/E56C/R59C/E63C-Fr immobilized with gold ions. | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | Authors: | Hishikawa, Y, Maity, B, Ito, N, Abe, S, Lu, D, Ueno, T. | Deposit date: | 2020-03-19 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Design of Multinuclear Gold Binding Site at the Two-fold Symmetric Interface of the Ferritin Cage Chem Lett., 49, 2021
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1JDA
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![BU of 1jda by Molmil](/molmil-images/mine/1jda) | MALTOTETRAOSE-FORMING EXO-AMYLASE | Descriptor: | 1,4-ALPHA MALTOTETRAHYDROLASE, CALCIUM ION | Authors: | Yoshioka, Y, Hasegawa, K, Matsuura, Y, Katsube, Y, Kubota, M. | Deposit date: | 1997-06-16 | Release date: | 1997-10-15 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of a mutant maltotetraose-forming exo-amylase cocrystallized with maltopentaose. J.Mol.Biol., 271, 1997
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5V04
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![BU of 5v04 by Molmil](/molmil-images/mine/5v04) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rII) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V0A
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![BU of 5v0a by Molmil](/molmil-images/mine/5v0a) | Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVIII) | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V08
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![BU of 5v08 by Molmil](/molmil-images/mine/5v08) | Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with 5' recessed-end DNA (rVI) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.812 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V09
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![BU of 5v09 by Molmil](/molmil-images/mine/5v09) | Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVII) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | Authors: | Shi, Y, Beese, L.S. | Deposit date: | 2017-02-28 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8ITG
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7SZK
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![BU of 7szk by Molmil](/molmil-images/mine/7szk) | Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex | Descriptor: | (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Shin, Y, Murakami, K.S. | Deposit date: | 2021-11-28 | Release date: | 2022-07-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infect Dis., 8, 2022
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6IOV
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![BU of 6iov by Molmil](/molmil-images/mine/6iov) | The ligand binding domain of Mlp37 with arginine | Descriptor: | ARGININE, Methyl-accepting chemotaxis (MCP) signaling domain protein | Authors: | Takahashi, Y, Sumita, K, Nishiyama, S, Kawagishi, I, Imada, K. | Deposit date: | 2018-10-31 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.351 Å) | Cite: | Structural basis of the binding affinity of chemoreceptors Mlp24p and Mlp37p for various amino acids. Biochem.Biophys.Res.Commun., 523, 2020
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6IOQ
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![BU of 6ioq by Molmil](/molmil-images/mine/6ioq) | The ligand binding domain of Mlp24 with glycine | Descriptor: | CALCIUM ION, GLYCINE, Methyl-accepting chemotaxis protein | Authors: | Takahashi, Y, Sumita, K, Nishiyama, S, Kawagishi, I, Imada, K. | Deposit date: | 2018-10-31 | Release date: | 2019-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.143 Å) | Cite: | Calcium Ions Modulate Amino Acid Sensing of the Chemoreceptor Mlp24 ofVibrio cholerae. J. Bacteriol., 201, 2019
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6IOU
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![BU of 6iou by Molmil](/molmil-images/mine/6iou) | The ligand binding domain of Mlp24 with serine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Methyl-accepting chemotaxis protein, ... | Authors: | Takahashi, Y, Sumita, K, Nishiyama, S, Kawagishi, I, Imada, K. | Deposit date: | 2018-10-31 | Release date: | 2019-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Calcium Ions Modulate Amino Acid Sensing of the Chemoreceptor Mlp24 ofVibrio cholerae. J. Bacteriol., 201, 2019
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