4W7H
 
 | | Crystal Structure of DEH Reductase A1-R Mutant | | 分子名称: | Carbonyl reductase | | 著者 | Takase, R, Mikami, B, Kawai, S, Murata, K, Hashimoto, W. | | 登録日 | 2014-08-22 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structure-based Conversion of the Coenzyme Requirement of a Short-chain Dehydrogenase/Reductase Involved in Bacterial Alginate Metabolism.
J.Biol.Chem., 289, 2014
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7VVL
 | | PTH-bound human PTH1R in complex with Gs (class2) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7VVN
 | | PTH-bound human PTH1R in complex with Gs (class4) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7VVK
 | | PTH-bound human PTH1R in complex with Gs (class1) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7VVM
 | | PTH-bound human PTH1R in complex with Gs (class3) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7VVJ
 | | PTHrP-bound human PTH1R in complex with Gs | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7VVO
 | | PTH-bound human PTH1R in complex with Gs (class5) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
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7YTB
 | | Crystal structure of Kin4B8 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Kin4B8, RETINAL | | 著者 | Murakoshi, S, Chazan, A, Shihoya, W, Beja, O, Nureki, O. | | 登録日 | 2022-08-14 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-03-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Phototrophy by antenna-containing rhodopsin pumps in aquatic environments.
Nature, 615, 2023
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8YEK
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4
Mol.Cell, 2024
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8YEJ
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer | | 分子名称: | GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4
Mol.Cell, 2024
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8YEL
 | | Cryo-EM structure of the channelrhodopsin GtCCR4 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cation channel rhodopsin 4, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4
Mol.Cell, 2024
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5H6U
 | | Structure of alginate-binding protein AlgQ2 in complex with an alginate pentasaccharide | | 分子名称: | AlgQ2, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | | 著者 | Uenishi, K, Kaneko, A, Maruyama, Y, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2016-11-15 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate
J. Biol. Chem., 292, 2017
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1XM5
 | | Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054 | | 分子名称: | Hypothetical UPF0054 protein ybeY, NICKEL (II) ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Shi, W, Ramagopal, U.A, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-10-01 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The ybeY protein from Escherichia coli is a metalloprotein.
Acta Crystallogr.,Sect.F, 61, 2005
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2A0Y
 | | Structure of human purine nucleoside phosphorylase H257D mutant | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | | 登録日 | 2005-06-17 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
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2A0W
 | | Structure of human purine nucleoside phosphorylase H257G mutant | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | | 登録日 | 2005-06-17 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
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2A0X
 | | Structure of human purine nucleoside phosphorylase H257F mutant | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | | 登録日 | 2005-06-17 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
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3GNE
 | | Crystal structure of alginate lyase vAL-1 from Chlorella virus | | 分子名称: | CITRATE ANION, GLYCEROL, VAL-1 | | 著者 | Ogura, K, Yamasaki, M, Hashidume, T, Yamada, T, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2009-03-17 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structure of family 14 polysaccharide lyase with pH-dependent modes of action
J.Biol.Chem., 284, 2009
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7D20
 | | Cryo-EM structure of SET8-CENP-A-nucleosome complex | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | | 登録日 | 2020-09-15 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase.
Life Sci Alliance, 4, 2021
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7D1Z
 | | Cryo-EM structure of SET8-nucleosome complex | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | | 登録日 | 2020-09-15 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase.
Life Sci Alliance, 4, 2021
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4TQV
 | | Crystal structure of a bacterial ABC transporter involved in the import of the acidic polysaccharide alginate | | 分子名称: | AlgM1, AlgM2, AlgS | | 著者 | Maruyama, Y, Itoh, T, Kaneko, A, Nishitani, Y, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2014-06-12 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (4.504 Å) | | 主引用文献 | Structure of a Bacterial ABC Transporter Involved in the Import of an Acidic Polysaccharide Alginate
Structure, 23, 2015
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4TQU
 | | Crystal structure of a bacterial ABC transporter involved in the import of the acidic polysaccharide alginate | | 分子名称: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, AlgM1, AlgM2, ... | | 著者 | Maruyama, Y, Itoh, T, Kaneko, A, Nishitani, Y, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2014-06-12 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.204 Å) | | 主引用文献 | Structure of a Bacterial ABC Transporter Involved in the Import of an Acidic Polysaccharide Alginate
Structure, 23, 2015
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7CJ3
 | | Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL | | 著者 | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | | 登録日 | 2020-07-09 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into the mechanism of rhodopsin phosphodiesterase.
Nat Commun, 11, 2020
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7CLJ
 | | Crystal structure of Thermoplasmatales archaeon heliorhodopsin E108D mutant | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, RETINAL, SULFATE ION, ... | | 著者 | Tanaka, T, Shihoya, W, Yamashita, K, Nureki, O. | | 登録日 | 2020-07-21 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for unique color tuning mechanism in heliorhodopsin.
Biochem.Biophys.Res.Commun., 533, 2020
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8ZH8
 | | Human GPR103 -Gq complex bound to QRFP26 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Iwama, A, Akasaka, H, Sano, F.K, Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-05-10 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.
Nat Commun, 15, 2024
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8XGR
 | | ETB-eGt complex bound to endothelin-1 | | 分子名称: | Camelid antibody VHH fragment, Endothelin receptor type B, Endothelin-1, ... | | 著者 | Oshima, H.S, Sano, F.K, Akasaka, H, Iwama, A, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-15 | | 公開日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Optimizing cryo-EM structural analysis of G i -coupling receptors via engineered G t and Nb35 application.
Biochem.Biophys.Res.Commun., 693, 2024
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