5YGX
 
 | | Structure of BACE1 in complex with N-(3-((4R,5R,6S)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide | | 分子名称: | Beta-secretase 1, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Nakahara, K, Fuchino, K, Komano, K, Asada, N, Tadano, G, Hasegawa, T, Yamamoto, T, Sako, Y, Ogawa, M, Unemura, C, Hosono, M, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K. | | 登録日 | 2017-09-27 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine beta-Secretase (BACE1) Inhibitors via Active Conformation Stabilization
J. Med. Chem., 61, 2018
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1VEK
 | | Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA | | 分子名称: | ubiquitin-specific protease 14, putative | | 著者 | Higuchi, Y, Abe, T, Hirota, H, Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-03-31 | | 公開日 | 2004-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA
To be Published
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1VCS
 | | Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus] | | 分子名称: | Vesicle transport through interaction with t-SNAREs homolog 1A | | 著者 | Abe, T, Hirota, H, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-03-10 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]
To be Published
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3A6P
 | | Crystal structure of Exportin-5:RanGTP:pre-miRNA complex | | 分子名称: | 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ... | | 著者 | Okada, C, Yamashita, E, Lee, S.J, Shibata, S, Katahira, J, Nakagawa, A, Yoneda, Y, Tsukihara, T. | | 登録日 | 2009-09-07 | | 公開日 | 2009-12-08 | | 最終更新日 | 2012-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | A high-resolution structure of the pre-microRNA nuclear export machinery
Science, 326, 2009
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5WZP
 | | Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free | | 分子名称: | Alpha-N-acetylgalactosaminidase, CALCIUM ION, ZINC ION | | 著者 | Sato, M, Arakawa, T, Ashida, H, Fushinobu, S. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017
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5WZQ
 | | Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - quadruple mutant | | 分子名称: | Alpha-N-acetylgalactosaminidase, GLYCEROL, ZINC ION | | 著者 | Sato, M, Arakawa, T, Ashida, H, Fushinobu, S. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017
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3UG3
 | | Crystal structure of alpha-L-arabinofuranosidase from Thermotoga maritima ligand free form | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, ... | | 著者 | Im, D.-H, Miyazaki, K, Wakagi, T, Fushinobu, S. | | 登録日 | 2011-11-02 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structures of Glycoside Hydrolase Family 51 alpha-L-Arabinofuranosidase from Thermotoga maritima
Biosci.Biotechnol.Biochem., 76, 2012
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1VDL
 | | Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 25 | | 著者 | Doi-Katayama, Y, Hirota, H, Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-03-23 | | 公開日 | 2004-09-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA
To be Published
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1V5L
 | | Solution structure of PDZ domain of mouse Alpha-actinin-2 associated LIM protein | | 分子名称: | PDZ and LIM domain 3; actinin alpha 2 associated LIM protein | | 著者 | Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-25 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of PDZ domain of mouse Alpha-actinin-2 associated LIM protein
To be Published
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1V5T
 | | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein | | 分子名称: | 8430435I17Rik Protein | | 著者 | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-25 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein
To be Published
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1V86
 | | Solution structure of the ubiquitin domain from mouse D7Wsu128e protein | | 分子名称: | DNA segment, Chr 7, Wayne State University 128, ... | | 著者 | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-12-29 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin domain from mouse D7Wsu128e protein
To be Published
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3X1W
 | | Ras-related protein Rap1B with GDP | | 分子名称: | CADMIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Noguchi, H, Ikegami, T, Akashi, S, Park, S.Y, Tame, J.R.H, Unzai, S. | | 登録日 | 2014-12-02 | | 公開日 | 2015-06-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The structure and conformational switching of Rap1B
Biochem.Biophys.Res.Commun., 462, 2015
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1X6A
 | | Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2) | | 分子名称: | LIM domain kinase 2, ZINC ION | | 著者 | Nameki, N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)
To be Published
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1X6C
 | | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 | | 分子名称: | Tyrosine-protein phosphatase, non-receptor type 6 | | 著者 | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1
To be Published
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3UG4
 | | Crystal structure of alpha-L-arabinofuranosidase from Thermotoga maritima arabinose complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, alpha-L-arabinofuranose | | 著者 | Im, D.-H, Miyazaki, K, Wakagi, T, Fushinobu, S. | | 登録日 | 2011-11-02 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal Structures of Glycoside Hydrolase Family 51 alpha-L-Arabinofuranosidase from Thermotoga maritima
Biosci.Biotechnol.Biochem., 76, 2012
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1X69
 | | Solution structures of the SH3 domain of human Src substrate cortactin | | 分子名称: | cortactin isoform a | | 著者 | Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the SH3 domain of human Src substrate cortactin
To be Published
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1X6E
 | | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 24 | | 分子名称: | ZINC ION, Zinc finger protein 24 | | 著者 | Sato, M, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 24
To be Published
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3UG5
 | | Crystal structure of alpha-L-arabinofuranosidase from Thermotoga maritima xylose complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, beta-D-xylopyranose | | 著者 | Im, D.-H, Miyazaki, K, Wakagi, T, Fushinobu, S. | | 登録日 | 2011-11-02 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Glycoside Hydrolase Family 51 alpha-L-Arabinofuranosidase from Thermotoga maritima
Biosci.Biotechnol.Biochem., 76, 2012
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3X27
 | | Structure of McbB in complex with tryptophan | | 分子名称: | Cucumopine synthase, TRYPTOPHAN | | 著者 | Mori, T, Sahashi, S, Morita, H, Abe, I. | | 登録日 | 2014-12-10 | | 公開日 | 2015-10-28 | | 最終更新日 | 2015-11-04 | | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | | 主引用文献 | Structural Basis for beta-Carboline Alkaloid Production by the Microbial Homodimeric Enzyme McbB
Chem.Biol., 22, 2015
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5WZN
 | | Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Alpha-N-acetylgalactosaminidase, CALCIUM ION, ... | | 著者 | Sato, M, Arakawa, T, Ashida, H, Fushinobu, S. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017
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3AK4
 | | Crystal structure of NADH-dependent quinuclidinone reductase from agrobacterium tumefaciens | | 分子名称: | NADH-dependent quinuclidinone reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Miyakawa, T, Kataoka, M, Takeshita, D, Nomoto, F, Nagata, K, Shimizu, S, Tanokura, M. | | 登録日 | 2010-07-07 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of NADH-dependent quinuclidinone reductase from Agrobacterium tumefaciens
To be Published
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1V95
 | | Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein) | | 分子名称: | Nuclear receptor coactivator 5 | | 著者 | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-01-20 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)
To be Published
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1UL7
 | | Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3 | | 分子名称: | MAP/microtubule affinity-regulating kinase 3 | | 著者 | Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-10 | | 公開日 | 2004-03-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the kinase-associated domain 1 of mouse microtubule-associated protein/microtubule affinity-regulating kinase 3
Protein Sci., 15, 2006
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1VAE
 | | Solution structure of the PDZ domain of mouse Rhophilin-2 | | 分子名称: | rhophilin, Rho GTPase binding protein 2 | | 著者 | Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-02-14 | | 公開日 | 2004-08-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the PDZ domain of mouse Rhophilin-2
To be Published
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1V2Y
 | | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold | | 分子名称: | 3300001G02Rik protein | | 著者 | Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-10-17 | | 公開日 | 2004-04-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold
To be Published
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