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PDB: 1470 件

3IH8
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Crystal Structure Analysis of Mglu in its native form
分子名称: Salt-tolerant glutaminase
著者Yoshimune, K, Shirakihara, Y.
登録日2009-07-29
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product l-glutamate and its activator Tris
Febs J., 277, 2010
3IHB
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Crystal Structure Analysis of Mglu in its tris and glutamate form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTAMIC ACID, Salt-tolerant glutaminase
著者Yoshimune, K, Shirakihara, Y.
登録日2009-07-29
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product l-glutamate and its activator Tris
Febs J., 277, 2010
4DOQ
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Crystal structure of the complex of Porcine Pancreatic Trypsin with 1/2SLPI
分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Antileukoproteinase, CALCIUM ION, ...
著者Fukushima, K, Takimoto-Kamimura, M.
登録日2012-02-10
公開日2013-08-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure basis 1/2SLPI and porcine pancreas trypsin interaction
J.SYNCHROTRON RADIAT., 20, 2013
4U6O
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STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2
分子名称: PHOSPHATE ION, Polymerase basic protein 2
著者Fukushima, K, Takimoto-Kamimura, M.
登録日2014-07-29
公開日2015-10-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2
To Be Published
8IMR
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Structure of ligand-free human macrophage migration inhibitory factor
分子名称: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H.
登録日2023-03-07
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis
To Be Published
8GW8
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the human PTH1 receptor bound to an intracellular biased agonist
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Kobayashi, K, Kusakizako, T, Okamoto, H.H, Nureki, O.
登録日2022-09-16
公開日2023-06-14
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Class B1 GPCR activation by an intracellular agonist.
Nature, 618, 2023
4YVH
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Crystal Structure of H. influenzae TrmD in complex with sinefungin
分子名称: SINEFUNGIN, tRNA (guanine-N(1)-)-methyltransferase
著者Yoshida, K, Ito, T, Yokoyama, S.
登録日2015-03-20
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YVI
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Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA
分子名称: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase
著者Yoshida, K, Ito, T, Yokoyama, S.
登録日2015-03-20
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YVJ
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Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA variant (G36U)
分子名称: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase
著者Yoshida, K, Ito, T, Yokoyama, S.
登録日2015-03-20
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YVK
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Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA variant (G36C)
分子名称: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase
著者Yoshida, K, Ito, T, Yokoyama, S.
登録日2015-03-20
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc.Natl.Acad.Sci.USA, 112, 2015
5B5K
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BU of 5b5k by Molmil
Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Izumo sperm-egg fusion protein 1
著者Nishimura, K, Han, L, De Sanctis, D, Jovine, L.
登録日2016-05-11
公開日2016-07-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins.
Curr.Biol., 26, 2016
4PDN
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Crystal structure of E. coli YfcM
分子名称: MAGNESIUM ION, Uncharacterized protein
著者Kobayashi, K, Ishii, R, Ishitani, R, Nureki, O.
登録日2014-04-19
公開日2015-03-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.448 Å)
主引用文献The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation.
Nucleic Acids Res., 42, 2014
8V7O
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Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
分子名称: #58 heavy chain, #58 light chain, Hemagglutinin
著者Nagashima, K.A, Mousa, J.J.
登録日2023-12-04
公開日2024-04-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024
6LU4
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Crystal structure of the substrate binding protein from Microbacterium hydrocarbonoxydans complexed with propylparaben
分子名称: Substrate binding protein, propyl 4-hydroxybenzoate
著者Shimamura, K, Akiyama, T, Yokoyama, K, Takenoya, M, Ito, S, Sasaki, Y, Yajima, S.
登録日2020-01-25
公開日2020-03-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of substrate recognition by the substrate binding protein (SBP) of a hydrazide transporter, obtained from Microbacterium hydrocarbonoxydans.
Biochem.Biophys.Res.Commun., 525, 2020
3WXM
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BU of 3wxm by Molmil
Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kobayashi, K, Ishitani, R, Nureki, O.
登録日2014-08-04
公開日2014-09-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex
Proc.Natl.Acad.Sci.USA, 107, 2010
3VMF
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Archaeal protein
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kobayashi, K, Saito, K, Ishitani, R, Ito, K, Nureki, O.
登録日2011-12-12
公開日2012-07-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for translation termination by archaeal RF1 and GTP-bound EF1alpha complex
Nucleic Acids Res., 40, 2012
7EHZ
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BU of 7ehz by Molmil
Structure of human NNMT in complex with macrocyclic peptide 2
分子名称: Nicotinamide N-methyltransferase, macrocyclic peptide 2
著者Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M.
登録日2021-03-30
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
7EGU
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Structure of human NNMT in complex with macrocyclic peptide X
分子名称: Nicotinamide N-methyltransferase, macrocyclic peptide X
著者Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M.
登録日2021-03-26
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
5BUP
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BU of 5bup by Molmil
Crystal structure of the ZP-C domain of mouse ZP2
分子名称: ACETATE ION, Zona pellucida sperm-binding protein 2
著者Nishimura, K, Jovine, L.
登録日2015-06-04
公開日2016-01-27
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献A structured interdomain linker directs self-polymerization of human uromodulin.
Proc.Natl.Acad.Sci.USA, 113, 2016
7EI2
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Structure of human NNMT in complex with macrocyclic peptide 8
分子名称: Nicotinamide N-methyltransferase, macrocyclic peptide 8
著者Hayashi, K, Mikamiyama, H, Uehara, S, Yamamoto, S, Cary, D, Nishikawa, J, Ueda, T, Ozasa, H, Mihara, K, Yoshimura, N, Kawai, T, Ono, T, Yamamoto, S, Fumoto, M.
登録日2021-03-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.
Acs Med.Chem.Lett., 12, 2021
6MTI
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BU of 6mti by Molmil
Synaptotagmin-1 C2A, C2B domains and SNARE-pin proteins (5CCI) individually docked into Cryo-EM map of C2AB-SNARE complexes helically organized on lipid nanotube surface in presence of Mg2+
分子名称: MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ...
著者Grushin, K, Wang, J, Coleman, J, Rothman, J, Sindelar, C, Krishnakumar, S.
登録日2018-10-19
公開日2019-04-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (10.4 Å)
主引用文献Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin.
Nat Commun, 10, 2019
4F1N
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Crystal structure of Kluyveromyces polysporus Argonaute with a guide RNA
分子名称: KpAGO, RNA 5'-R(P*UP*AP*AP*AP*AP*AP*AP*AP*A)-3'
著者Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J.
登録日2012-05-07
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.187 Å)
主引用文献Structure of yeast Argonaute with guide RNA.
Nature, 486, 2012
2ENY
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Solution structure of the ig-like domain (2735-2825) of human obscurin
分子名称: Obscurin
著者Nagashima, K, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-28
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the ig-like domain (2735-2825) of human obscurin
To be Published
1DET
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RIBONUCLEASE T1 CARBOXYMETHYLATED AT GLU 58 IN COMPLEX WITH 2'GMP
分子名称: GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1, SODIUM ION
著者Ishikawa, K, Suzuki, E, Tanokura, M, Takahashi, K.
登録日1996-02-20
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of ribonuclease T1 carboxymethylated at Glu58 in complex with 2'-GMP.
Biochemistry, 35, 1996
1IW8
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Crystal Structure of a mutant of acid phosphatase from Escherichia blattae (G74D/I153T)
分子名称: SULFATE ION, acid phosphatase
著者Ishikawa, K, Mihara, Y, Shimba, N, Ohtsu, N, Kawasaki, H, Suzuki, E, Asano, Y.
登録日2002-04-22
公開日2002-09-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Enhancement of nucleoside phosphorylation activity in an acid phosphatase
PROTEIN ENG., 15, 2002

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