4WM7
 
 | | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ... | | 著者 | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2014-10-08 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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7OUO
 | | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | | 分子名称: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | | 著者 | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | | 登録日 | 2021-06-12 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.212 Å) | | 主引用文献 | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
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5MIM
 | | Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n | | 分子名称: | 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Dahms, S.O, Guan-Sheng, J, Than, M.E. | | 登録日 | 2016-11-28 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
ACS Chem. Biol., 12, 2017
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5HN2
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5HNJ
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6Z18
 | | Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; R32 form | | 分子名称: | RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG | | 著者 | Ruszkowski, M, Sekula, B, Mao, S, Haruehanroengra, P, Sheng, J. | | 登録日 | 2020-05-12 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA.
Nucleic Acids Res., 48, 2020
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6WY3
 | | Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; P212121 form | | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*(LV2)P*GP*CP*CP*GP*G)-3') | | 著者 | Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J. | | 登録日 | 2020-05-12 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.647 Å) | | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA.
Nucleic Acids Res., 48, 2020
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5HNQ
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6WY2
 | | Crystal structure of RNA-10mer: CCGG(N4-methyl-C)GCCGG | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, RNA-10mer: CCGG(4-methyl-C)GCCGG | | 著者 | Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J. | | 登録日 | 2020-05-12 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.928 Å) | | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA.
Nucleic Acids Res., 48, 2020
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5TKO
 | | RNA heptamer duplex with one 2'-5'-linkage | | 分子名称: | COBALT (II) ION, RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') | | 著者 | Luo, Z, Sheng, J. | | 登録日 | 2016-10-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | RNA heptamer duplex with one 2'-5'-linkage
To Be Published
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4WM8
 | | Crystal Structure of Human Enterovirus D68 | | 分子名称: | DECANOIC ACID, VP1, VP2, ... | | 著者 | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2014-10-08 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
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3BM0
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5U0Q
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4F4N
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4FP6
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2H05
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2HC7
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5TDJ
 | | RNA decamer duplex with four 2'-5'-linkages | | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3'), STRONTIUM ION | | 著者 | Luo, Z, Sheng, J. | | 登録日 | 2016-09-19 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into RNA duplexes with multiple 2 -5 -linkages.
Nucleic Acids Res., 45, 2017
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7D31
 | | The TBA-Pb2+ complex in P41212 space group | | 分子名称: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | 著者 | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | 登録日 | 2020-09-18 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | | 主引用文献 | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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5TDK
 | | RNA decamer duplex with eight 2'-5'-linkages | | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3'), STRONTIUM ION | | 著者 | Luo, Z, Sheng, J. | | 登録日 | 2016-09-19 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural insights into RNA duplexes with multiple 2 -5 -linkages.
Nucleic Acids Res., 45, 2017
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7D32
 | | The TBA-Pb2+ complex in P41212 space group | | 分子名称: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | 著者 | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | 登録日 | 2020-09-18 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.707 Å) | | 主引用文献 | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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7D33
 | | The Pb2+ complexed structure of TBA G8C mutant | | 分子名称: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*CP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | | 著者 | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | | 登録日 | 2020-09-18 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.117 Å) | | 主引用文献 | Structure-guided development of Pb 2+ -binding DNA aptamers.
Sci Rep, 12, 2022
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6LT0
 | | cryo-EM structure of C9ORF72-SMCR8-WDR41 | | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | | 著者 | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | | 登録日 | 2020-01-21 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5BNP
 | | Crystal structure of human enterovirus D68 in complex with 3'SLN | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G. | | 登録日 | 2015-05-26 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
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5BNN
 | | Crystal structure of human enterovirus D68 in complex with 6'SL | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G. | | 登録日 | 2015-05-26 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
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