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PDB: 210 件

4GN9
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mouse SMP30/GNL-glucose complex
分子名称: CALCIUM ION, Regucalcin, SULFATE ION, ...
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
4GN8
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mouse SMP30/GNL-1,5-AG complex
分子名称: 1,5-anhydro-D-glucitol, CALCIUM ION, Regucalcin, ...
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
8ZYO
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Cryo-EM Structure of astemizole-bound hERG Channel
分子名称: 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Potassium voltage-gated channel subfamily H member 2
著者Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T.
登録日2024-06-18
公開日2024-09-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors.
Structure, 2024
8ZYQ
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Cryo-EM Structure of pimozide-bound hERG Channel
分子名称: 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1~{H}-benzimidazol-2-one, Potassium voltage-gated channel subfamily H member 2
著者Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T.
登録日2024-06-18
公開日2024-09-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors.
Structure, 2024
8ZYN
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BU of 8zyn by Molmil
Cryo-EM Structure of inhibitor-free hERG Channel
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T.
登録日2024-06-18
公開日2024-09-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors.
Structure, 2024
8ZYP
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Cryo-EM Structure of E-4031-bound hERG Channel
分子名称: Potassium voltage-gated channel subfamily H member 2, ~{N}-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidin-4-yl]carbonylphenyl]methanesulfonamide
著者Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T.
登録日2024-06-18
公開日2024-09-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors.
Structure, 2024
4GNA
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mouse SMP30/GNL-xylitol complex
分子名称: CALCIUM ION, Regucalcin, SULFATE ION, ...
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
4GNC
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human SMP30/GNL-1,5-AG complex
分子名称: 1,5-anhydro-D-glucitol, CALCIUM ION, Regucalcin
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
2V9Z
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Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity
分子名称: HALOALKANE DEHALOGENASE
著者Koudelakova, T, Prokop, Z, Sato, Y, Lapkouski, M, Chovancova, E, Monincova, M, Jesenska, A, Emmer, J, Senda, T, Nagata, Y, Kuta Smatanova, I, Damborsky, J.
登録日2007-08-28
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Rational Engineering of Rhodococcus Haloalkane Dehalogenase with Enhanced Enantioselectivity
To be Published
4GNB
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human SMP30/GNL
分子名称: CALCIUM ION, Regucalcin
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
4GN7
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BU of 4gn7 by Molmil
mouse SMP30/GNL
分子名称: CALCIUM ION, Regucalcin, SULFATE ION
著者Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T.
登録日2012-08-17
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase
Plos One, 8, 2013
5X94
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BU of 5x94 by Molmil
Crystal structure of SHP2_SH2-CagA EPIYA_D peptide complex
分子名称: Cag pathogenicity island protein, Tyrosine-protein phosphatase non-receptor type 11
著者Senda, M, Senda, T.
登録日2017-03-05
公開日2017-09-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins.
Cell Rep, 20, 2017
5X7B
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Crystal structure of SHP2_SH2-CagA EPIYA_C peptide complex
分子名称: CagA, Tyrosine-protein phosphatase non-receptor type 11
著者Senda, M, Senda, T.
登録日2017-02-24
公開日2017-09-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins.
Cell Rep, 20, 2017
3X06
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BU of 3x06 by Molmil
Crystal structure of PIP4KIIBETA T201M complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X05
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BU of 3x05 by Molmil
Crystal structure of PIP4KIIBETA T201M complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X03
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BU of 3x03 by Molmil
Crystal structure of PIP4KIIBETA complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X01
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BU of 3x01 by Molmil
Crystal structure of PIP4KIIBETA complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X09
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BU of 3x09 by Molmil
Crystal structure of PIP4KIIBETA F205L complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X02
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BU of 3x02 by Molmil
Crystal structure of PIP4KIIBETA complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X04
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BU of 3x04 by Molmil
Crystal structure of PIP4KIIBETA complex with GMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X0A
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BU of 3x0a by Molmil
Crystal structure of PIP4KIIBETA F205L complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X08
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BU of 3x08 by Molmil
Crystal structure of PIP4KIIBETA N203A complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X0B
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Crystal structure of PIP4KIIBETA I368A complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X0C
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BU of 3x0c by Molmil
Crystal structure of PIP4KIIBETA I368A complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016
3X07
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BU of 3x07 by Molmil
Crystal structure of PIP4KIIBETA N203A complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T.
登録日2014-10-09
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61, 2016

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