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PDB: 792 件

2I3W
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Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of S729C mutant
分子名称: GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID
著者Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E.
登録日2006-08-21
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
1FN8
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FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION
分子名称: GLY-ALA-ARG, GLYCEROL, SULFATE ION, ...
著者Rypniewski, W.R, Oestergaard, P, Noerregaard-Madsen, M, Dauter, M, Wilson, K.S.
登録日2000-08-21
公開日2001-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.81 Å)
主引用文献Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.
Acta Crystallogr.,Sect.D, 57, 2001
1TXT
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Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase
分子名称: 3-hydroxy-3-methylglutaryl-CoA synthase, ACETOACETYL-COENZYME A
著者Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M.
登録日2004-07-06
公開日2004-08-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism
J.Biol.Chem., 279, 2004
1DD8
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CRYSTAL STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I FROM ESCHERICHIA COLI
分子名称: BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I
著者Olsen, J.G, Kadziola, A, von Wettstein-Knowles, P, Siggaard-Andersen, M, Lindquist, Y, Larsen, S.
登録日1999-11-09
公開日1999-11-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I.
FEBS Lett., 460, 1999
1TVZ
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Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus
分子名称: 3-hydroxy-3-methylglutaryl-CoA synthase, SULFATE ION
著者Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M.
登録日2004-06-30
公開日2004-08-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism
J.Biol.Chem., 279, 2004
1T84
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Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
分子名称: (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein
著者Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K.
登録日2004-05-11
公開日2004-07-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
1OKF
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NMR structure of an alpha-L-LNA:RNA hybrid
分子名称: 5'-D(*CP*ATLP*GP*AP*ATLP*AP*ATLP*GP*CP)-3', 5'-R(*GP*CP*AP*UP*AP*UP*CP*AP*GP)-3'
著者Nielsen, J.T, Stein, P.C, Petersen, M.
登録日2003-07-23
公開日2003-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Structure of an Alpha-L-Lna:RNA Hybrid: Structural Implications for Rnase H Recognition
Nucleic Acids Res., 31, 2003
2BNX
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Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1
分子名称: CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1
著者Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K.
登録日2005-04-05
公開日2005-06-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
1FY5
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Fusarium oxysporum trypsin at atomic resolution
分子名称: GLY-ALA-LYS, GLYCEROL, SULFATE ION, ...
著者Rypniewski, W.R, Oestergaard, P, Noerregaard-Madsen, M, Dauter, M, Wilson, K.S.
登録日2000-09-28
公開日2001-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.81 Å)
主引用文献Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.
Acta Crystallogr.,Sect.D, 57, 2001
1JRB
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The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-13
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1RNF
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X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4
分子名称: PROTEIN (RIBONUCLEASE 4)
著者Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Rueth, F.X, Coll, M.
登録日1998-10-29
公開日1999-10-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity.
J.Mol.Biol., 285, 1999
2K42
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Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effector
分子名称: ESPFU, Wiskott-Aldrich syndrome protein
著者Cheng, H.-C, Skehan, B.M, Campellone, K.G, Leong, J.M, Rosen, M.K.
登録日2008-05-27
公開日2008-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).
Nature, 454, 2008
1PLG
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EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID
分子名称: IGG2A=KAPPA=
著者Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R.
登録日1995-04-24
公開日1996-04-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
1JRC
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The N67A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-13
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1H0Q
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NMR solution structure of a fully modified locked nucleic acid (LNA) hybridized to RNA
分子名称: 5-D(*(LKC)P*(TLN)P*(LCG)P*(LCA)P*(TLN)P*(LCA)P* (TLN)P*(LCG)P*(LCC))-3, 5-R(*GP*CP*AP*UP*AP*UP*CP*AP*G)-3
著者Rasmussen, J, Petersen, M, Nielsen, K.E, Kumar, R, Wengel, J, Jacobsen, J.P.
登録日2002-06-27
公開日2003-07-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Studies of Fully Modified Locked Nucleic Acid (Lna) Hybrids: Solution Structure of an Lna:RNA Hybrid and Characterization of an Lna:RNA Hybrid
Bioconjug.Chem., 15, 2004
1QRR
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CRYSTAL STRUCTURE OF SQD1 PROTEIN COMPLEX WITH NAD AND UDP-GLUCOSE
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ...
著者Mulichak, A.M, Theisen, M.J, Essigmann, B, Benning, C, Garavito, R.M.
登録日1999-06-15
公開日1999-11-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose.
Proc.Natl.Acad.Sci.USA, 96, 1999
1NF3
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Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
分子名称: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ...
著者Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R.
登録日2002-12-12
公開日2003-03-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
2JIC
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High resolution structure of xylanase-II from one micron beam experiment
分子名称: XYLANASE-II
著者Moukhametzianov, R, Burghammer, M, Edwards, P.C, Petitdemange, S, Popov, D, Fransen, M, Schertler, G.F, Riekel, C.
登録日2007-02-27
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Protein Crystallography with a Micrometre-Sized Synchrotron-Radiation Beam.
Acta Crystallogr.,Sect.D, 64, 2008
2QPU
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Sugar tongs mutant S378P in complex with acarbose
分子名称: 1,2-ETHANEDIOL, 1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
1P2N
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Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
分子名称: Chymotrypsinogen A, Pancreatic trypsin inhibitor, SULFATE ION
著者Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O.
登録日2003-04-15
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
2R59
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Leukotriene A4 hydrolase complexed with inhibitor RB3041
分子名称: ACETIC ACID, Leukotriene A-4 hydrolase, N-{(2S)-3-[(R)-[(1R)-1-amino-2-phenylethyl](hydroxy)phosphoryl]-2-benzylpropanoyl}-L-phenylalanine, ...
著者Tholander, F, Haeggstrom, J.Z, Thunnissen, M, Muroya, A, Roques, B.P, Fournie-Zaluski, M.C.
登録日2007-09-03
公開日2008-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design.
Chem.Biol., 15, 2008
1P2O
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Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
分子名称: Chymotrypsinogen A, Pancreatic trypsin inhibitor, SULFATE ION
著者Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O.
登録日2003-04-15
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
1PBZ
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DE NOVO DESIGNED PEPTIDE-METALLOPORPHYRIN COMPLEX, SOLUTION STRUCTURE
分子名称: COPROPORPHYRIN I CONTAINING CO(III), De novo designed cyclic peptide
著者Wang, J, Rosenblatt, M.M, Suslick, K.S.
登録日2003-05-15
公開日2003-12-09
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献De novo designed cyclic-peptide heme complexes
Proc.Natl.Acad.Sci.USA, 100, 2003
1IIB
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CRYSTAL STRUCTURE OF IIBCELLOBIOSE FROM ESCHERICHIA COLI
分子名称: ENZYME IIB OF THE CELLOBIOSE-SPECIFIC PHOSPHOTRANSFERASE SYSTEM
著者Van Montfort, R.L.M, Pijning, T, Kalk, K.H, Reizer, J, Saier, M.H, Thunnissen, M.M.G.M, Robillard, G.T, Dijkstra, B.W.
登録日1996-12-23
公開日1997-12-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases.
Structure, 5, 1997
2IOV
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Bright-state structure of the reversibly switchable fluorescent protein Dronpa
分子名称: Fluorescent protein Dronpa
著者Stiel, A.C, Trowitzsch, S, Weber, G, Andresen, M, Eggeling, C, Hell, S.W, Jakobs, S, Wahl, M.C.
登録日2006-10-11
公開日2006-12-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants
Biochem.J., 402, 2007

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