4RS7
 
 | |
4S0R
 | | Structure of GS-TnrA complex | | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | | Authors: | Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K. | | Deposit date: | 2015-01-04 | | Release date: | 2015-03-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
4RS8
 | |
6UEQ
 | | Structure of TBP bound to C-C mismatch containing TATA site | | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), SULFATE ION, ... | | Authors: | Schumacher, M.A, Al-Hashimi, H. | | Deposit date: | 2019-09-22 | | Release date: | 2020-09-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
|
|
7U3A
 | | Structure of the Streptomyces venezuelae GlgX-c-di-GMP complex | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | | Authors: | Schumacher, M.A. | | Deposit date: | 2022-02-26 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.34 Å) | | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
|
|
7U3D
 | | Structure of S. venezuelae GlgX-c-di-GMP-acarbose complex (4.6) | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | | Authors: | Schumacher, M.A. | | Deposit date: | 2022-02-27 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
|
|
7U3B
 | | Structure of S. venezuelae GlgX bound to c-di-GMP and acarbose (pH 8.5) | | Descriptor: | 4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranosyl)-beta-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX, ... | | Authors: | Schumacher, M.A, Tschowri, N. | | Deposit date: | 2022-02-26 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.
Nat Commun, 13, 2022
|
|
7U39
 | |
6P5R
 | | Structure of T. brucei MERS1-GDP complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial edited mRNA stability factor 1 | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-05-30 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei.
Rna, 26, 2020
|
|
6PFJ
 | | Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-06-21 | | Release date: | 2019-11-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
|
|
6PFV
 | | Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-06-22 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
|
|
1WET
 | | STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX | | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | | Authors: | Schumacher, M.A, Glasfeld, A, Zalkin, H, Brennan, R.G. | | Deposit date: | 1997-04-27 | | Release date: | 1997-11-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
J.Biol.Chem., 272, 1997
|
|
5E1L
 | | Structural and functional analysis of the E. coli FtsZ interacting protein, ZapC, reveals insight into molecular properties of a novel Z ring stabilizing protein | | Descriptor: | Cell division protein ZapC | | Authors: | Schumacher, M.A, Huang, K.-H, Tchorzewski, L, Zeng, W, Janakiraman, A. | | Deposit date: | 2015-09-29 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC.
J.Biol.Chem., 291, 2016
|
|
6UNX
 | | Structure of E. coli FtsZ(L178E)-GTP complex | | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-10-13 | | Release date: | 2020-02-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP.
Acta Crystallogr.,Sect.F, 76, 2020
|
|
6NL1
 | | Structure of T. brucei MERS1 protein in its apo form | | Descriptor: | Mitochondrial edited mRNA stability factor 1, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-07 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.297 Å) | | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei.
Rna, 26, 2020
|
|
6NJQ
 | | Structure of TBP-Hoogsteen containing DNA complex | | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1 | | Authors: | Schumacher, M.A, Stelling, A. | | Deposit date: | 2019-01-04 | | Release date: | 2019-10-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Infrared Spectroscopic Observation of a G-C+Hoogsteen Base Pair in the DNA:TATA-Box Binding Protein Complex Under Solution Conditions.
Angew.Chem.Int.Ed.Engl., 58, 2019
|
|
6NON
 | | Structure of Cyanthece apo McdA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-16 | | Release date: | 2019-04-24 | | Last modified: | 2019-06-26 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
|
|
6NOP
 | | Structure of Cyanothece McdA(D38A)-ATP complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-16 | | Release date: | 2019-04-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
|
|
6NOO
 | | Structure of Cyanothece McdA-AMPPNP complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maintenance of carboxysome positioning A protein, ... | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-16 | | Release date: | 2019-04-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
|
|
6NOY
 | | Structure of Cyanothece McdB | | Descriptor: | Maintenance of carboxysome positioning B protein, Mcsb | | Authors: | Schumacher, M.A. | | Deposit date: | 2019-01-16 | | Release date: | 2019-04-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.46 Å) | | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
|
|
6WEG
 | |
2PUD
 | | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | | Deposit date: | 1997-10-04 | | Release date: | 1998-05-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
|
|
2PUC
 | | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | | Deposit date: | 1997-10-04 | | Release date: | 1998-05-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
|
|
8SUK
 | | Structure of Rhodococcus sp. USK13 DarR-c-di-AMP complex | | Descriptor: | DNA (5'-D(*AP*A)-3'), DarR, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2023-05-12 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding.
Nat Commun, 14, 2023
|
|
8T5Y
 | |
