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PDB: 22 件
4XFO
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BU of 4xfo by Molmil
Structure of an amyloid-forming segment TAVVTN from human Transthyretin
分子名称: Amyloid-forming peptide TAVVTN
著者Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
登録日2014-12-27
公開日2015-10-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFN
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Structure of an Amyloid forming peptide AEVVFT from Human Transthyretin
分子名称: Amyloid forming peptide AEVVFT
著者Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
登録日2014-12-27
公開日2015-10-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4UNV
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BU of 4unv by Molmil
Covalent dimer of lambda variable domains
分子名称: IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION
著者Brumshtein, B, Esswein, S, Landau, M, Ryan, C, Whitelegge, J, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2014-08-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
2DPK
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BU of 2dpk by Molmil
The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GUANIDINE, ...
著者Abramson, J, Sawaya, M.
登録日2006-05-12
公開日2006-06-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the primary Ca2+ sensor of the na+/ca2+ exchanger reveals a novel Ca2+ binding motif.
J.Biol.Chem., 281, 2006
3LE4
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BU of 3le4 by Molmil
Crystal structure of the DGCR8 dimerization domain
分子名称: Microprocessor complex subunit DGCR8
著者Senturia, R, Cascio, D, Sawaya, M, Guo, F.
登録日2010-01-14
公開日2010-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structure of the dimerization domain of DiGeorge Critical Region 8
Protein Sci., 19, 2010
4TLU
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BU of 4tlu by Molmil
Crystal Structure of Human Transthyretin Ala108Trp Mutant
分子名称: CHLORIDE ION, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2015-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Human Transthyretin Ala108Trp Mutant
to be published
4TNG
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Crystal Structure of Human Transthyretin Thr119Met Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-06-04
公開日2015-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Transthyretin Thr119Met Mutant
to be published
4TNF
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BU of 4tnf by Molmil
Crystal Structure of Human Transthyretin Lys15Trp Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-06-03
公開日2015-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Transthyretin Lys15Trp Mutant
to be published
5WMJ
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BU of 5wmj by Molmil
KVWGSI segment from Superoxide Dismutase 1,residues 30-35
分子名称: Superoxide dismutase [Cu-Zn], trifluoroacetic acid
著者Sangwan, S, Sawaya, M, Eisenberg, D.
登録日2017-07-28
公開日2018-03-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
1S3Q
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BU of 1s3q by Molmil
Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus
分子名称: ZINC ION, ferritin
著者Johnson, E, Cascio, D, Sawaya, M, Schroeder, I.
登録日2004-01-13
公開日2005-04-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Structure, 13, 2005
4TL5
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BU of 4tl5 by Molmil
Crystal Structure of Human Transthyretin Ser85Pro Mutant
分子名称: CHLORIDE ION, SODIUM ION, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-28
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TKW
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BU of 4tkw by Molmil
Crystal Structure of Human Transthyretin Leu55Pro Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-27
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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BU of 4tl4 by Molmil
Crystal Structure of Human Transthyretin Val30Met Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-28
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
3LOZ
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BU of 3loz by Molmil
Crystal structure of Beta 2 Microglobulin amyloidogenic segment LSFSKD
分子名称: Beta-2-microglobulin segment LSFSKD
著者Liu, C, Sawaya, M, Eisenberg, D.
登録日2010-02-04
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
Nat.Struct.Mol.Biol., 18, 2011
4TNE
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BU of 4tne by Molmil
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
分子名称: GLYCEROL, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-06-03
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLS
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BU of 4tls by Molmil
Crystal Structure of Human Transthyretin Glu92Pro Mutant
分子名称: GLYCEROL, PHOSPHATE ION, SODIUM ION, ...
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLT
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BU of 4tlt by Molmil
Crystal structure of human transthyretin
分子名称: MAGNESIUM ION, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLK
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BU of 4tlk by Molmil
Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ...
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TM9
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BU of 4tm9 by Molmil
Crystal Structure of Human Transthyretin Thr119Trp Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-31
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
7UCP
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BU of 7ucp by Molmil
computationally designed macrocycle
分子名称: computationally designed cyclic peptide D8.3.p2
著者Bhardwaj, G, Baker, D, Rettie, S, Glynn, C, Sawaya, M.
登録日2022-03-17
公開日2022-09-14
最終更新日2022-09-28
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Accurate de novo design of membrane-traversing macrocycles.
Cell, 185, 2022
6WX1
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BU of 6wx1 by Molmil
Antigen Binding Fragment of OKT9
分子名称: GLYCEROL, OKT9 Fab Heavy Chain, OKT9 Fab Light Chain
著者Rodriguez, J.A, Helguera, G, Sawaya, M, Cascio, D, Collazo, M, Flores, M, Zink, S, Ferrero, S, Payes, C, Fuentes, D, Short, C.
登録日2020-05-09
公開日2021-05-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain.
J.Virol., 95, 2021
6WLA
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BU of 6wla by Molmil
Antigen binding fragment of ch128.1
分子名称: Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL
著者Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C.
登録日2020-04-18
公開日2021-03-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.
Nat Commun, 13, 2022

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件を2024-10-30に公開中

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