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PDB: 52 件
4IL4
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The pentameric ligand-gated ion channel GLIC in complex with Se-DDM
分子名称: ACETATE ION, CHLORIDE ION, Proton-gated ion channel, ...
著者Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4HFI
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BU of 4hfi by Molmil
The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-10-05
公開日2013-02-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4NPQ
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BU of 4npq by Molmil
The resting-state conformation of the GLIC ligand-gated ion channel
分子名称: Proton-gated ion channel
著者Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M.
登録日2013-11-22
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NPP
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The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms
分子名称: NICKEL (II) ION, Proton-gated ion channel
著者Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M.
登録日2013-11-22
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
Proc.Natl.Acad.Sci.USA, 111, 2014
4ILA
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BU of 4ila by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium
分子名称: ACETATE ION, CESIUM ION, CHLORIDE ION, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4IL9
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BU of 4il9 by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with bromide
分子名称: ACETATE ION, BROMIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4ILB
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BU of 4ilb by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
8C5Z
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RPA tetrameric supercomplex with AROD-OB-1
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
登録日2023-01-10
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8C5Y
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RPA tetrameric supercomplex from Pyrococcus abyssi
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
登録日2023-01-10
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8AAJ
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BU of 8aaj by Molmil
Crystal structure of the Pyrococcus abyssi RPA (apo form)
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Legrand, P, Madru, C, Sauguet, L.
登録日2022-07-01
公開日2023-05-03
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8AA9
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Crystal structure of the Rpa1 AROD-OB-1 domains
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Replication factor A
著者Madru, C, Legrand, P, Sauguet, L.
登録日2022-06-30
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8AAS
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BU of 8aas by Molmil
Crystal structure of the Pyrococcus abyssi RPA trimerization core bound to poly-dT20 ssDNA
分子名称: CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, ...
著者Madru, C, Legrand, P, Sauguet, L.
登録日2022-07-01
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8PPU
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BU of 8ppu by Molmil
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches
分子名称: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ...
著者Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
登録日2023-07-10
公開日2023-12-20
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PPV
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BU of 8ppv by Molmil
Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches
分子名称: DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ...
著者Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
登録日2023-07-10
公開日2023-12-20
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PPT
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BU of 8ppt by Molmil
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch
分子名称: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ...
著者Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
登録日2023-07-10
公開日2023-12-20
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8OEJ
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BU of 8oej by Molmil
Extended RPA-DNA nucleoprotein filament
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Sauguet, L.
登録日2023-03-10
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (7.96 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8OEL
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BU of 8oel by Molmil
Condensed RPA-DNA nucleoprotein filament
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Sauguet, L.
登録日2023-03-10
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (8.24 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
6T7Y
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BU of 6t7y by Molmil
Structure of PCNA bound to cPIP motif of DP2 from P. abyssi
分子名称: DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD
著者Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L.
登録日2019-10-23
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
5HCJ
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BU of 5hcj by Molmil
Cationic Ligand-Gated Ion Channel
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, ...
著者Shahsavar, A, Sauguet, L, Delarue, M.
登録日2016-01-04
公開日2016-04-13
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Sites of Anesthetic Inhibitory Action on a Cationic Ligand-Gated Ion Channel.
Structure, 24, 2016
6T8H
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BU of 6t8h by Molmil
Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi
分子名称: DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ...
著者Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L.
登録日2019-10-24
公開日2020-03-04
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
5HCM
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The GLIC pentameric Ligand-Gated Ion Channel 2-21' cross-linked mutant complexed to bromoform
分子名称: DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, TRIBROMOMETHANE
著者Shahsavar, A, Sauguet, L, Delarue, M.
登録日2016-01-04
公開日2016-04-13
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Sites of Anesthetic Inhibitory Action on a Cationic Ligand-Gated Ion Channel.
Structure, 24, 2016
6T7X
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BU of 6t7x by Molmil
Crystal structure of PCNA from P. abyssi
分子名称: DNA polymerase sliding clamp
著者Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L.
登録日2019-10-23
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
4QH4
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BU of 4qh4 by Molmil
The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in acetate buffer at pH3
分子名称: ACETATE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, ...
著者Fourati, Z, Delarue, M, Sauguet, L.
登録日2014-05-26
公開日2015-07-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
To be Published
4QH1
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BU of 4qh1 by Molmil
The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate
分子名称: BROMIDE ION, Proton-gated ion channel, SODIUM ION, ...
著者Fourati, Z, Delarue, M, Sauguet, L.
登録日2014-05-26
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015
4QH5
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The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M, Sauguet, L.
登録日2014-05-26
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015

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件を2024-06-12に公開中

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