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PDB: 111 results

7UIZ
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BU of 7uiz by Molmil
ClpAP complex bound to ClpS N-terminal extension, class IIc
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ...
Authors:Kim, S, Fei, X, Sauer, R.T, Baker, T.A.
Deposit date:2022-03-29
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
7UIV
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BU of 7uiv by Molmil
ClpAP complex bound to ClpS N-terminal extension, class IIa
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ...
Authors:Kim, S, Fei, X, Sauer, R.T, Baker, T.A.
Deposit date:2022-03-29
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
2HDD
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BU of 2hdd by Molmil
ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX
Descriptor: DNA (5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*C P*CP*GP*GP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN Q50K)
Authors:Tucker-Kellogg, L, Rould, M.A, Chambers, K.A, Ades, S.E, Sauer, R.T, Pabo, C.O.
Deposit date:1998-02-10
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity.
Structure, 5, 1997
6WRF
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BU of 6wrf by Molmil
ClpX-ClpP complex bound to GFP-ssrA, recognition complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Fei, X, Sauer, R.T.
Deposit date:2020-04-29
Release date:2020-11-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates.
Elife, 9, 2020
6WSG
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BU of 6wsg by Molmil
ClpX-ClpP complex bound to ssrA-tagged GFP, intermediate complex
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, Green fluorescent protein, ...
Authors:Fei, X, Sauer, R.T.
Deposit date:2020-04-30
Release date:2020-11-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates.
Elife, 9, 2020
6WR2
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BU of 6wr2 by Molmil
ClpP and ClpX IGF loop in ClpX-ClpP complex bound to ssrA tagged GFP
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit
Authors:Fei, X, Sauer, R.T.
Deposit date:2020-04-29
Release date:2020-11-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates.
Elife, 9, 2020
4I4L
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BU of 4i4l by Molmil
Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-27
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.6981 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4U0G
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BU of 4u0g by Molmil
Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist
Descriptor: ADEP-2B5Me, ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, ...
Authors:Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T.
Deposit date:2014-07-11
Release date:2014-10-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1978 Å)
Cite:Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
4U0H
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BU of 4u0h by Molmil
Crystal Structure of M. tuberculosis ClpP1P1
Descriptor: ATP-dependent Clp protease proteolytic subunit 1, SULFATE ION
Authors:Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T.
Deposit date:2014-07-11
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2479 Å)
Cite:Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
4I34
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BU of 4i34 by Molmil
Crystal Structure of W-W-W ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-23
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.1218 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I81
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BU of 4i81 by Molmil
Crystal Structure of ATPgS bound ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-12-01
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.8182 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
1TWB
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BU of 1twb by Molmil
SspB disulfide crosslinked to an ssrA degradation tag
Descriptor: Stringent starvation protein B homolog, ssrA peptide
Authors:Bolon, D.N, Grant, R.A, Baker, T.A, Sauer, R.T.
Deposit date:2004-06-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleotide-Dependent Substrate Handoff from the SspB Adaptor to the AAA+ ClpXP Protease.
Mol.Cell, 16, 2004
1U9P
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BU of 1u9p by Molmil
Permuted single-chain Arc
Descriptor: pArc
Authors:Tabtiang, R.K, Cezairliyan, B.O, Grant, R.A, Cochrane, J.C, Sauer, R.T.
Deposit date:2004-08-10
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Consolidating critical binding determinants by noncyclic rearrangement of protein secondary structure
Proc.Natl.Acad.Sci.Usa, 102, 2005
1YFN
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BU of 1yfn by Molmil
Versatile modes of peptide recognition by the AAA+ adaptor protein SspB- the crystal structure of a SspB-RseA complex
Descriptor: Sigma-E factor negative regulatory protein, Stringent starvation protein B
Authors:Levchenko, I, Grant, R.A, Flynn, J.M, Sauer, R.T, Baker, T.A.
Deposit date:2005-01-03
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
Nat.Struct.Mol.Biol., 12, 2005
5JI2
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BU of 5ji2 by Molmil
HslU L199Q in HslUV complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ...
Authors:Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
Deposit date:2016-04-21
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.307 Å)
Cite:A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
5JI3
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BU of 5ji3 by Molmil
HslUV complex
Descriptor: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV
Authors:Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
Deposit date:2016-04-21
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
3LH1
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BU of 3lh1 by Molmil
Q191A mutant of the DegS-deltaPDZ
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.507 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGU
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BU of 3lgu by Molmil
Y162A mutant of the DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGY
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BU of 3lgy by Molmil
R178A mutant of the DegS-deltaPDZ protease
Descriptor: CHLORIDE ION, MAGNESIUM ION, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGV
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BU of 3lgv by Molmil
H198P mutant of the DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGW
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BU of 3lgw by Molmil
H198P/T167V double mutant of DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGI
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BU of 3lgi by Molmil
Structure of the protease domain of DegS (DegS-deltaPDZ) at 1.65 A
Descriptor: PHOSPHATE ION, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-20
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.652 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGT
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BU of 3lgt by Molmil
Y162A/H198P double mutant of DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LH3
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BU of 3lh3 by Molmil
DFP modified DegS delta PDZ
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3DNJ
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BU of 3dnj by Molmil
The structure of the Caulobacter crescentus ClpS protease adaptor protein in complex with a N-end rule peptide
Descriptor: ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION, synthetic N-end rule peptide
Authors:Wang, K, Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A.
Deposit date:2008-07-02
Release date:2008-11-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The molecular basis of N-end rule recognition.
Mol.Cell, 32, 2008

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