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PDB: 41 results
7LCF
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BU of 7lcf by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, with pyruvate bound in the active site and L-lysine bound at the allosteric site in C121 space group
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, MAGNESIUM ION
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2021-01-10
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:B-factors: L- lysine and R, R- bisLysine allosterically inhibit Cj. DHDPS Enzyme by decreasing its protein dynamics
To Be Published
7KG9
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BU of 7kg9 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-10-16
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni
To Be Published
7KLY
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BU of 7kly by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-01
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:H59 PLAYS THE MOST VITAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS ENZYME
To Be Published
7KKG
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BU of 7kkg by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84D mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-10-27
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A TIGHT DIMER INTERFACE N84 RESIDUE, PLAYS A CRITICAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS
To Be Published
7KLS
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BU of 7kls by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59A mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, LYSINE, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-10-31
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:H59 PLAYS THE MOST VITAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS ENZYME
To Be Published
7KKT
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BU of 7kkt by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84D mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-10-28
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A TIGHT DIMER INTERFACE N84 RESIDUE, PLAYS A CRITICAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS
To Be Published
7KK1
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BU of 7kk1 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84A mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-10-27
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A TIGHT DIMER INTERFACE N84 RESIDUE, PLAYS A CRITICAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS
To Be Published
7KLT
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BU of 7klt by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-01
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:H59 PLAYS THE MOST VITAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS ENZYME
To Be Published
7KN9
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BU of 7kn9 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88A mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-04
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND.
To Be Published
7KOC
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BU of 7koc by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88Q mutant with pyruvate bound in the active site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-08
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND.
To Be Published
7KPE
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BU of 7kpe by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88Q mutant with pyruvate bound in the active site and R,R-bislysine at the allosteric site
Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-11
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND.
To Be Published
7KM1
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BU of 7km1 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
Authors:Saran, S, Majdi Yazdi, M, Sanders, D.A.R.
Deposit date:2020-11-02
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:H59 PLAYS THE MOST VITAL ROLE IN THE TRANSMISSION OF THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS ENZYME
To Be Published
7KN2
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BU of 7kn2 by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88A mutant with pyruvate bound in the active site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-04
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND
To Be Published
7KWN
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BU of 7kwn by Molmil
Dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site in C2221 space group
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-12-01
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS.
To Be Published
7KXG
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BU of 7kxg by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and L-histidine bound at the allosteric site
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-12-03
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site
To Be Published
7KWF
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BU of 7kwf by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Sanders, D.A.R.
Deposit date:2020-11-30
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:ALLOSTERIC SITE RESIDUE 'H56' CAPS THE INHIBITOR AT THE TIGHT DIMER INTERFACE FOR TRANSMITTING THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS
To Be Published
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PDB entries from 2024-07-03

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