6EPA
 
 | | Structure of dNCS-1 bound to the NCS-1/Ric8a protein/protein interaction regulator IGS-1.76 | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, FI18190p1, ... | | Authors: | Sanchez-Barrena, M.J, Daniel, M, Infantes, L. | | Deposit date: | 2017-10-11 | | Release date: | 2018-08-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
J. Med. Chem., 61, 2018
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6QI4
 | | NCS-1 bound to a ligand | | Descriptor: | 2-(1~{H}-indol-3-yl)-~{N}-[(~{E})-(4-nitro-3-oxidanyl-phenyl)methylideneamino]ethanamide, ACETATE ION, CALCIUM ION, ... | | Authors: | Sanchez-Barrena, M.J, Blanco-Gabella, P. | | Deposit date: | 2019-01-17 | | Release date: | 2019-07-17 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library.
Nat Commun, 10, 2019
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2EHB
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1V1F
 | | Structure of the Arabidopsis thaliana SOS3 complexed with Calcium(II) and Manganese(II) ions | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCINEURIN B-LIKE PROTEIN 4, CALCIUM ION, ... | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Zhu, J.K, Albert, A. | | Deposit date: | 2004-04-15 | | Release date: | 2005-01-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Structure of the Arabidopsis Thaliana SOS3: Molecular Mechanism of Sensing Calcium for Salt Stress Response
J.Mol.Biol., 345, 2005
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1V1G
 | | Structure of the Arabidopsis thaliana SOS3 complexed with Calcium(II) ion | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCINEURIN B-LIKE PROTEIN 4, CALCIUM ION, ... | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Zhu, J.K, Albert, A. | | Deposit date: | 2004-04-15 | | Release date: | 2005-01-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Structure of the Arabidopsis Thaliana SOS3: Molecular Mechanism of Sensing Calcium for Salt Stress Response
J.Mol.Biol., 345, 2005
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1O84
 | | Crystal Structure of Bacteriocin AS-48. N-decyl-beta-D-maltoside Bound. | | Descriptor: | DECANE, GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, ... | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Valdivia, E, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-25 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
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1O83
 | | Crystal Structure of Bacteriocin AS-48 at pH 7.5, phosphate bound. Crystal form I | | Descriptor: | GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, PHOSPHATE ION | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Valdivia, E, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-25 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
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1O82
 | | X-RAY STRUCTURE OF BACTERIOCIN AS-48 AT PH 4.5. SULPHATE BOUND FORM | | Descriptor: | GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, SULFATE ION | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Martinez-Bueno, M, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-22 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
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3ZPV
 | | Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain | | Descriptor: | PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION | | Authors: | Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M. | | Deposit date: | 2013-03-02 | | Release date: | 2013-10-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
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8ALM
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8AHY
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8ALH
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5FYX
 | | Crystal structure of Drosophila NCS-1 bound to penothiazine FD16 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ... | | Authors: | Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | | Deposit date: | 2016-03-10 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5G08
 | | Crystal structure of Drosophila NCS-1 bound to chlorpromazine | | Descriptor: | 1,2-ETHANEDIOL, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CALCIUM ION, ... | | Authors: | Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | | Deposit date: | 2016-03-17 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5AAR
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5AAN
 | | Crystal structure of Drosophila NCS-1 bound to penothiazine FD44 | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, CG5907-PA, ... | | Authors: | Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | | Deposit date: | 2015-07-27 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2VPB
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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4CZT
 | | Crystal structure of the kinase domain of CIPK23 | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CBL-INTERACTING SERINE/THREONINE-PROTEIN KINASE 23, SULFATE ION | | Authors: | Chaves-Sanjuan, A, Sanchez-Barrena, M.J, Albert, A. | | Deposit date: | 2014-04-22 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis of the Regulatory Mechanism of the Plant Cipk Family of Protein Kinases Controlling Ion Homeostasis and Abiotic Stress
Proc.Natl.Acad.Sci.USA, 111, 2014
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2VPG
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Bienz, M, Evans, P. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VPE
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VP7
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SULFATE ION, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-26 | | Release date: | 2008-06-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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4CZU
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4D28
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2VPD
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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4BY4
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