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PDB: 44 results

6RKO
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BU of 6rko by Molmil
Cryo-EM structure of the E. coli cytochrome bd-I oxidase at 2.68 A resolution
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-I ubiquinol oxidase subunit 1, ...
Authors:Safarian, S, Hahn, A, Kuehlbrandt, W, Michel, H.
Deposit date:2019-04-30
Release date:2019-10-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Active site rearrangement and structural divergence in prokaryotic respiratory oxidases.
Science, 366, 2019
5IR6
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BU of 5ir6 by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
Descriptor: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
Authors:Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
Deposit date:2016-03-12
Release date:2016-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
5DOQ
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BU of 5doq by Molmil
The structure of bd oxidase from Geobacillus thermodenitrificans
Descriptor: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ...
Authors:Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H.
Deposit date:2015-09-11
Release date:2016-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
Science, 352, 2016
7NKZ
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BU of 7nkz by Molmil
Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ...
Authors:Safarian, S, Wu, D, Krause, K.L, Michel, H.
Deposit date:2021-02-19
Release date:2021-09-22
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Nat Commun, 12, 2021
8B4O
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BU of 8b4o by Molmil
Cryo-EM structure of cytochrome bd oxidase from C. glutamicum
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome BD ubiquinol oxidase subunit I, Cytochrome bd-type quinol oxidase subunit II, ...
Authors:Grund, T.N, Kusumoto, T, Michel, H, Sakamoto, J, Safarian, S.
Deposit date:2022-09-20
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Cryo-EM structure of cytochrome bd oxidase from C. glutamicum
To be published
6HFB
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BU of 6hfb by Molmil
Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.
Descriptor: CESIUM ION, Uncharacterized protein
Authors:Nonaka, T, Zakrzewska, S, Safarian, S, Michel, H.
Deposit date:2018-08-21
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Inward-facing conformation of a multidrug resistance MATE family transporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
7OY2
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BU of 7oy2 by Molmil
High resolution structure of cytochrome bd-II oxidase from E. coli
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(2~{E},6~{E},10~{Z},14~{E},18~{E},22~{E},26~{E})-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]naphthalene-1,4-dione, CARDIOLIPIN, ...
Authors:Grund, T.N, Wu, D, Bald, D, Michel, H, Safarian, S.
Deposit date:2021-06-23
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
8QCX
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BU of 8qcx by Molmil
Cryo-EM structure of the inward-facing FLVCR2
Descriptor: Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCY
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BU of 8qcy by Molmil
Cryo-EM structure of the outward-facing FLVCR2
Descriptor: Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCS
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BU of 8qcs by Molmil
Cryo-EM structure of the inward-facing FLVCR1
Descriptor: Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QD0
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BU of 8qd0 by Molmil
Cryo-EM structure of the inward-facing choline-bound FLVCR2
Descriptor: CHOLINE ION, Heme transporter FLVCR2
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCT
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BU of 8qct by Molmil
Cryo-EM structure of the inward-facing choline-bound FLVCR1
Descriptor: CHOLINE ION, Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-08-28
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8R8T
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BU of 8r8t by Molmil
Cryo-EM structure of the inward-facing ethanolamine-bound FLVCR1
Descriptor: ETHANOLAMINE, Heme transporter FLVCR1
Authors:Weng, T.-H, Wu, D, Safarian, S.
Deposit date:2023-11-29
Release date:2024-04-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
7ZDR
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BU of 7zdr by Molmil
IF(apo/as isolated) conformation of CydDC mutant (H85A.C) in AMP-PNP(CydD) bound state (Dataset-16)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDB
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BU of 7zdb by Molmil
IF(heme/bound) conformation of CydDC in ADP+Pi(CydC)/ATP(CydD) bound state (Dataset-2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDG
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BU of 7zdg by Molmil
IF(heme/confined) conformation of CydDC (Dataset-5)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, HEME B/C
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDS
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BU of 7zds by Molmil
IF(apo/as isolated) conformation of CydDC mutant (E500Q.C) (Dataset-18)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDV
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BU of 7zdv by Molmil
IF(apo/as isolated) conformation of CydDC mutant (E500Q.C) in AMP-PNP(CydD) bound state (Dataset-20)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDF
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BU of 7zdf by Molmil
IF(heme/confined) conformation of CydDC in AMP-PNP(CydD) bound state (Dataset-4)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDT
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BU of 7zdt by Molmil
Occ(apo/return) conformation of CydDC mutant (E500Q.C) in ATP(CydC) bound state (Dataset-18)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDE
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BU of 7zde by Molmil
IF(apo/as isolated) conformation of CydDC in AMP-PNP(CydD) bound state (Dataset-4)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZEC
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BU of 7zec by Molmil
IF(heme/confined) conformation of CydDC in ATP(CydD) bound state (Dataset-15)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-30
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDW
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BU of 7zdw by Molmil
IF(heme/confined) conformation of CydDC mutant (E500Q.C) in AMP-PNP(CydD) bound state (Dataset-22)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, HEME B/C, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDA
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BU of 7zda by Molmil
IF(apo/asym) conformation of CydDC in ADP+Pi(CydC)/ATP(CydD) bound state (Dataset-2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023
7ZDL
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BU of 7zdl by Molmil
IF(heme/coordinated) conformation of CydDC in AMP-PNP(CydC)/AMP-PNP(CydD) bound state (Dataset-8)
Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, HEME B/C, ...
Authors:Wu, D, Safarian, S.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Dissecting the conformational complexity and mechanism of a bacterial heme transporter.
Nat.Chem.Biol., 19, 2023

 

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