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PDB: 40 件
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
登録日2022-08-23
公開日2023-08-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7J
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BU of 8e7j by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2022-08-24
公開日2023-08-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8GF7
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BU of 8gf7 by Molmil
Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein
著者Balana, J.A, Nguyen, A.B, Saelices, L, Pratt, R.M.
登録日2023-03-07
公開日2023-11-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献O-GlcNAc forces an alpha-synuclein amyloid strain with notably diminished seeding and pathology.
Nat.Chem.Biol., 20, 2024
8G9R
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BU of 8g9r by Molmil
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2023-02-21
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8GBR
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BU of 8gbr by Molmil
Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2023-02-28
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8E7I
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BU of 8e7i by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR P24S amyloidosis patient
分子名称: Transthyretin protein
著者Nguyen, B.A, Saelices, L.
登録日2022-08-24
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Cardiac amyloid fibrils extracted from a variant ATTR P24S amyloidosis patient
To Be Published
8E7D
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BU of 8e7d by Molmil
Cryo-EM structure of wild-type transthyretin amyloid from heart tissue
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2022-08-23
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
8E7H
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BU of 8e7h by Molmil
Cryo-EM structure of cardiac amyloid fibril from a wild-type amyloidosis patient
分子名称: Transthyretin
著者Nguyen, B.A, Saelices, L.
登録日2022-08-23
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cardiac amyloid fibrils extracted from a wild-type ATTR amyloidosis patient
To Be Published
6C4O
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BU of 6c4o by Molmil
AMYLOID FORMING PEPTIDE TIAALLS FROM TRANSTHYRETIN
分子名称: THR-ILE-ALA-ALA-LEU-LEU-SER
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-12
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3T
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BU of 6c3t by Molmil
AMYLOID FORMING PEPTIDE AADTWE FROM TRANSTHYRETIN WITH ATTR-D38A MUTATION ASSOCIATED WITH A FAMILIAL FORM OF TRANSTHYRETIN AMYLOIDOSIS
分子名称: ALA-ALA-ASP-THR-TRP-GLU
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-10
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3S
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BU of 6c3s by Molmil
AMYLOID FORMING PEPTIDE YTIAAL FROM TRANSTHYRETIN
分子名称: TYR-THR-ILE-ALA-ALA-LEU
著者Sievers, S.A, Sawaya, M.R, Saelices, L, Eisenberg, D.S.
登録日2018-01-10
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6E70
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BU of 6e70 by Molmil
Structure of Wild Type Human Transthyretin in Complex with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, CALCIUM ION, Transthyretin
著者Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2018-07-25
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Structural Variants of Transthyretin
To Be Published
6E73
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BU of 6e73 by Molmil
Structure of Human Transthyretin Val30Met Mutant in Complex with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, ACETATE ION, Transthyretin
著者Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2018-07-25
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Structural Variants of Transthyretin
to be published
6E78
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BU of 6e78 by Molmil
Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
著者Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2018-07-25
公開日2019-07-31
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Structural Variants of Transthyretin
To Be Published
6E72
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BU of 6e72 by Molmil
Structure of Human Transthyretin Val30Met Mutant in Complex with Tafamidis
分子名称: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
著者Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2018-07-25
公開日2019-07-31
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Variants of Transthyretin
To Be Published
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件を2024-06-12に公開中

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