Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 859 件
4WG0
DownloadVisualize
BU of 4wg0 by Molmil
Crystal structure of a tridecameric superhelix
分子名称: CHOLIC ACID, Nuclear receptor coactivator 2, SULFATE ION
著者Rudolph, M.G, Uson, I, Schoch, G.
登録日2014-09-17
公開日2015-01-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure of a 13-fold superhelix (almost) determined from first principles.
Iucrj, 2, 2015
5MAO
DownloadVisualize
BU of 5mao by Molmil
HERA HELICASE RNA BINDING DOMAIN with TNCS in P212121
分子名称: Heat resistant RNA dependent ATPase, SULFATE ION
著者Rudolph, M.G, Klostermeier, D.
登録日2016-11-03
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal Structure of HERA CTD
To be published
4DDX
DownloadVisualize
BU of 4ddx by Molmil
Thermotoga maritima reverse gyrase, primitive monoclinic form
分子名称: Reverse gyrase, ZINC ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4DDU
DownloadVisualize
BU of 4ddu by Molmil
Thermotoga maritima reverse gyrase, C2 FORM 1
分子名称: Reverse gyrase, ZINC ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4DDQ
DownloadVisualize
BU of 4ddq by Molmil
Structural plasticity of the Bacillus subtilis GyrA homodimer
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA gyrase subunit A, POTASSIUM ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mapping the Spectrum of Conformational States of the DNA- and C-Gates in Bacillus subtilis Gyrase.
J.Mol.Biol., 425, 2013
4DDT
DownloadVisualize
BU of 4ddt by Molmil
Thermotoga maritima reverse gyrase, C2 FORM 2
分子名称: Reverse gyrase, ZINC ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4DDW
DownloadVisualize
BU of 4ddw by Molmil
Thermotoga maritima reverse gyrase, c-centered orthorhombic form
分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, Reverse gyrase, ...
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
3LLL
DownloadVisualize
BU of 3lll by Molmil
Crystal structure of mouse pacsin2 F-BAR domain
分子名称: CALCIUM ION, CHLORIDE ION, Protein kinase C and casein kinase substrate in neurons protein 2, ...
著者Rudolph, M.G.
登録日2010-01-29
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
J.Mol.Biol., 400, 2010
3MWL
DownloadVisualize
BU of 3mwl by Molmil
Q28E mutant of HERA N-terminal RecA-like domain in complex with 8-OXOADENOSINE
分子名称: 6-azanyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one, Heat resistant RNA dependent ATPase, SULFATE ION
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3MWJ
DownloadVisualize
BU of 3mwj by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, apo form
分子名称: Heat resistant RNA dependent ATPase, SULFATE ION
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3MWK
DownloadVisualize
BU of 3mwk by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP
分子名称: Heat resistant RNA dependent ATPase, SULFATE ION, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
著者Rudolph, M.G, Klostermeier, D.
登録日2010-05-06
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3NEJ
DownloadVisualize
BU of 3nej by Molmil
Q28E mutant of Hera RNA helicase N-terminal domain - perfectly twinned hexagonal form
分子名称: Heat resistant RNA dependent ATPase
著者Rudolph, M.G.
登録日2010-06-09
公開日2011-04-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3NBF
DownloadVisualize
BU of 3nbf by Molmil
Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP
分子名称: Heat resistant RNA dependent ATPase, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate
著者Rudolph, M.G, Klostermeier, D.
登録日2010-06-03
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
4DDV
DownloadVisualize
BU of 4ddv by Molmil
Thermotoga maritima reverse gyrase, triclinic form
分子名称: Reverse gyrase, ZINC ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-01-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4I68
DownloadVisualize
BU of 4i68 by Molmil
Crystal structure of the R444A / R449A double mutant of the HERA RNA helicase RRM domain
分子名称: CHLORIDE ION, Heat resistant RNA dependent ATPase, ZINC ION
著者Rudolph, M.G, Klostermeier, D.
登録日2012-11-29
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.
Nucleic Acids Res., 41, 2013
4I67
DownloadVisualize
BU of 4i67 by Molmil
Crystal structure of the RRM domain of RNA helicase HERA from T. thermophilus in complex with GGGC RNA
分子名称: 5'-R(P*GP*GP*GP*(RPC))-3', Heat resistant RNA dependent ATPase
著者Rudolph, M.G, Klostermeier, D.
登録日2012-11-29
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.
Nucleic Acids Res., 41, 2013
4I69
DownloadVisualize
BU of 4i69 by Molmil
Crystal structure of the K463A mutant of the RRM domain of RNA helicase HERA from T. thermophilus
分子名称: CHLORIDE ION, Heat resistant RNA dependent ATPase
著者Rudolph, M.G, Klostermeier, D.
登録日2012-11-29
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.
Nucleic Acids Res., 41, 2013
5EDC
DownloadVisualize
BU of 5edc by Molmil
human FABP4 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid at 1.29A
分子名称: 6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte, ...
著者Rudolph, M.G, Ehler, A.
登録日2015-10-21
公開日2016-03-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A Real-World Perspective on Molecular Design.
J.Med.Chem., 59, 2016
5EDB
DownloadVisualize
BU of 5edb by Molmil
human fatty acid binding protein 4 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid at 1.18A
分子名称: 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte
著者Rudolph, M.G, Ehler, A.
登録日2015-10-21
公開日2016-03-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献A Real-World Perspective on Molecular Design.
J.Med.Chem., 59, 2016
3OLF
DownloadVisualize
BU of 3olf by Molmil
Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-methylbenzoic acid
分子名称: 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-methylbenzoic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-26
公開日2011-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Bioorg.Med.Chem.Lett., 21, 2011
3OOF
DownloadVisualize
BU of 3oof by Molmil
Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid
分子名称: 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-31
公開日2011-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Bioorg.Med.Chem.Lett., 21, 2011
3P4X
DownloadVisualize
BU of 3p4x by Molmil
Helicase domain of reverse gyrase from Thermotoga maritima
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Rudolph, M.G, Klostermeier, D.
登録日2010-10-07
公開日2011-06-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The Conformational Flexibility of the Helicase-like Domain from Thermotoga maritima Reverse Gyrase Is Restricted by the Topoisomerase Domain.
Biochemistry, 50, 2011
3OKH
DownloadVisualize
BU of 3okh by Molmil
Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid
分子名称: 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-25
公開日2010-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes
Bioorg.Med.Chem.Lett., 21, 2010
3OMK
DownloadVisualize
BU of 3omk by Molmil
Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexyl-N-(2-methylphenyl)ethanamide
分子名称: (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexyl-N-(2-methylphenyl)ethanamide, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-27
公開日2011-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Bioorg.Med.Chem.Lett., 21, 2011
3OKI
DownloadVisualize
BU of 3oki by Molmil
Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide
分子名称: (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-25
公開日2010-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes
Bioorg.Med.Chem.Lett., 21, 2010

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon