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PDB: 566 件

8DQU
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Nanobody bound SARS-CoV-2 Nsp9
分子名称: Nanobody, Non-structural protein 9
著者Littler, D.R, Gully, B.S, Rossjohn, J.
登録日2022-07-20
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.45003176 Å)
主引用文献Inside-out: Antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9.
Plos One, 18, 2023
4BWG
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Structural basis of subtilase cytotoxin SubAB assembly
分子名称: GLYCEROL, SUBA, SUBTILASE CYTOTOXIN, ...
著者Le Nours, J, Paton, A.W, Byres, E, Troy, S, Herdman, B.P, Johnson, M.D, Paton, J.C, Rossjohn, J, Beddoe, T.
登録日2013-07-02
公開日2013-08-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Subtilase Cytotoxin Subab Assembly.
J.Biol.Chem., 288, 2013
6XCO
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Immune receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, GLYCEROL, ...
著者Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
登録日2020-06-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
6XCP
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Immune receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide, ...
著者Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
登録日2020-06-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
6XNG
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MHC-like protein complex structure
分子名称: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
登録日2020-07-02
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
8SOS
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Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Shahine, A, Rossjohn, J.
登録日2023-04-29
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions.
J Immunother Cancer, 11, 2023
5KBF
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cAMP bound PfPKA-R (141-441)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit, putative
著者Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J.
登録日2016-06-03
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
J. Biol. Chem., 291, 2016
8SHI
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Valpha3S1 Vbeta13S1 HLA C 0602 VRSRRCLRL
分子名称: Beta-2-microglobulin, MHC class I antigen (Fragment), T cell receptor alpha, ...
著者Littler, D.R, Anand, S, Vivian, J.P, Rossjohn, J.
登録日2023-04-14
公開日2023-06-28
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.90001726 Å)
主引用文献Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02.
J.Biol.Chem., 299, 2023
3LN4
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BU of 3ln4 by Molmil
Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2
分子名称: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ...
著者Theodossis, A, Gras, S, Rossjohn, J.
登録日2010-02-01
公開日2010-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.296 Å)
主引用文献The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
8SGM
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BU of 8sgm by Molmil
Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.50000215 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
8SGB
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.80001545 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
4DZB
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BU of 4dzb by Molmil
Mucosal-associated invariant T cell receptor, Valpha7.2Jalpha33-Vbeta2
分子名称: Valpha7.2-Jalpha33 (MAIT T cell receptor), Vbeta2 (MAIT T cell receptor)
著者Patel, O, Rossjohn, J.
登録日2012-03-01
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor.
J.Exp.Med., 209, 2012
6XQP
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Structure of human D462-E4 TCR in complex with human MR1-5-OP-RU
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, BROMIDE ION, Beta-2-microglobulin, ...
著者Awad, W, Rossjohn, J.
登録日2020-07-10
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Atypical TRAV1-2 - T cell receptor recognition of the antigen-presenting molecule MR1.
J.Biol.Chem., 295, 2020
8GLI
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BU of 8gli by Molmil
Crystal Structure of Human CD1b in Complex with Mycobacterial C85-GMM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-20-{(1R,2S)-2-[(17R,18R)-17-methoxy-18-methyldotriacontyl]cyclopropyl}-2-pentadecylicosanoyl]-alpha-L-galactopyranose, Beta-2-microglobulin, ...
著者Balaji, G, Rossjohn, J, Shahine, A.
登録日2023-03-22
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
4EI5
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BU of 4ei5 by Molmil
Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1
分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Patel, O, Gras, S, Rossjohn, J.
登録日2012-04-04
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor.
Nat.Immunol., 13, 2012
1LBK
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BU of 1lbk by Molmil
Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ...
著者Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M.
登録日2002-04-04
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
J.Mol.Biol., 325, 2003
5KSB
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T15-DQ8.5-glia-gamma1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DQ8.5-glia-gamma1 peptide, ...
著者Petersen, J, Rossjohn, J, Reid, H.H.
登録日2016-07-08
公開日2016-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
5KS9
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Bel502-DQ8-glia-alpha1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel502 TCR alpha TRAV20*01, Bel502 TCR beta TRBV9*01, ...
著者Petersen, J, Rossjohn, J, Reid, H.H.
登録日2016-07-08
公開日2016-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
5KSA
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Bel602-DQ8.5-glia-gamma1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel602 alpha TRAV20*01, Bel602 beta TRBV9*01, ...
著者Petersen, J, Rossjohn, J, Reid, H.H.
登録日2016-07-08
公開日2016-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
6XQQ
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Structure of human D462-E4 TCR
分子名称: GLYCEROL, TRAV12-2 alpha chain, TRBV29-1
著者Awad, W, Rossjohn, J.
登録日2020-07-10
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Atypical TRAV1-2 - T cell receptor recognition of the antigen-presenting molecule MR1.
J.Biol.Chem., 295, 2020
8TUB
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BU of 8tub by Molmil
HLA B7:02 with HPNGYKSLSTL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J.
登録日2023-08-16
公開日2024-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age.
Nat Commun, 15, 2024
1KGC
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Immune Receptor
分子名称: T-cell receptor alpha chain, T-cell receptor beta chain
著者Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2001-11-26
公開日2002-12-11
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance
STRUCTURE, 10, 2002
4EI6
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Structure of XV19 Valpha1-Vbeta16 Type-II Natural Killer T cell receptor
分子名称: Valpha1 XV19 Type II Natural Killer T cell receptor (mouse variable domain, human constant domain), Vbeta16 XV19 Type II Natural Killer T cell receptor (mouse variable domain
著者Patel, O, Rossjohn, J.
登録日2012-04-04
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor.
Nat.Immunol., 13, 2012
5J1A
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Antigen presenting molecule
分子名称: 3-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,2-diol, Beta-2-microglobulin, T-cell surface glycoprotein CD1a
著者Yongqing, T, Rossjohn, J, Le Nours, J, Marquez, E, Winau, F.
登録日2016-03-29
公開日2016-08-03
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献CD1a on Langerhans cells controls inflammatory skin disease.
Nat. Immunol., 17, 2016
5J6G
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Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
著者Berry, R, Rossjohn, J.
登録日2016-04-04
公開日2016-07-13
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016

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