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PDB: 146 results

6XR6
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BU of 6xr6 by Molmil
Abl 1b isoform active state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XR7
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BU of 6xr7 by Molmil
Abl isoform 1b inactive1 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XRG
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BU of 6xrg by Molmil
Abl 1b isoform inactive2 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-12
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
7MZY
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BU of 7mzy by Molmil
Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986
Descriptor: ACETATE ION, ALK tyrosine kinase receptor
Authors:Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
2KCV
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BU of 2kcv by Molmil
Solution nmr structure of tetratricopeptide repeat domain protein sru_0103 from salinibacter ruber, northeast structural genomics consortium (nesg) target srr115c
Descriptor: Tetratricopeptide repeat domain protein
Authors:Liu, G, Rossi, P, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-12-29
Release date:2009-01-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution nmr structure of tetratricopeptide repeat domain protein sru_0103 from salinibacter ruber, northeast structural genomics consortium (nesg) target srr115c
To be Published
2KCP
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BU of 2kcp by Molmil
SOLUTION STRUCTURE OF 30S RIBOSOMAL PROTEIN S8E; FROM Methanothermobacter thermautotrophicus, NORTHEASTSTRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET Tr71d
Descriptor: 30S ribosomal protein S8e
Authors:Liu, G, Rossi, P, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-12-24
Release date:2009-07-14
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF 30S RIBOSOMAL PROTEIN S8E FROM Methanothermobacter thermautotrophicus, NORTHEASTSTRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET
To be Published
2KEM
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BU of 2kem by Molmil
Extended structure of citidine deaminase domain of APOBEC3G
Descriptor: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
Authors:Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H.
Deposit date:2009-01-30
Release date:2009-06-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389, 2009
4UMC
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BU of 4umc by Molmil
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Descriptor: L-PHOSPHOLACTATE, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J.
Deposit date:2014-05-16
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.
Bioorg.Chem., 57, 2014
4UMB
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BU of 4umb by Molmil
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Descriptor: (2R)-2-(phosphonooxy)propanoic acid, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J.
Deposit date:2014-05-16
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.
Bioorg.Chem., 57, 2014
4UMA
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BU of 4uma by Molmil
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3 deoxy D arabino heptulosonate 7 phosphate synthase the importance of accommodating the active site water
Descriptor: (E)-2-METHYL-3-PHOSPHONOACRYLATE, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE
Authors:Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J.
Deposit date:2014-05-16
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.
Bioorg.Chem., 57, 2014
3IPF
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BU of 3ipf by Molmil
Crystal structure of the Q251Q8_DESHY protein from Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR8c.
Descriptor: uncharacterized protein
Authors:Vorobiev, S.M, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Andre, I, Rossi, P, Kennedy, M, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-08-17
Release date:2009-09-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Crystal structure of the Q251Q8_DESHY protein from Desulfitobacterium hafniense.
To be Published
6AMW
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BU of 6amw by Molmil
Abl1b Regulatory Module 'Activating' conformation
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Rossi, P, Saleh, T.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
6AMV
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BU of 6amv by Molmil
Abl 1b Regulatory Module 'inhibiting state'
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Saleh, T, Rossi, P.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
3LMO
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BU of 3lmo by Molmil
Crystal Structure of specialized acyl carrier protein (RPA2022) from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR324
Descriptor: Specialized acyl carrier protein
Authors:Forouhar, F, Rossi, P, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-01-31
Release date:2010-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations.
Biochemistry, 51, 2012
2MS4
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BU of 2ms4 by Molmil
Cyclophilin a complexed with a fragment of crk-ii
Descriptor: Peptide, Peptidyl-prolyl cis-trans isomerase A
Authors:Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C.
Deposit date:2014-07-22
Release date:2015-09-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway.
Nat.Chem.Biol., 12, 2016
5JTL
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BU of 5jtl by Molmil
The structure of chaperone SecB in complex with unstructured proPhoA
Descriptor: Alkaline phosphatase, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTN
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BU of 5jtn by Molmil
The structure of chaperone SecB in complex with unstructured proPhoA binding site c
Descriptor: Alkaline phosphatase, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
6PPT
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BU of 6ppt by Molmil
Structural Basis for Client Recognition and Activity of Hsp40 Chaperones
Descriptor: Alkaline phosphatase,Chaperone protein DnaJ 2 fusion
Authors:Jiang, Y, Rossi, P, Kalodimos, C.G.
Deposit date:2019-07-08
Release date:2019-09-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for client recognition and activity of Hsp40 chaperones.
Science, 365, 2019
5JTM
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BU of 5jtm by Molmil
The structure of chaperone SecB in complex with unstructured PhoA binding site a
Descriptor: Alkaline phosphatase, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTQ
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BU of 5jtq by Molmil
The structure of chaperone SecB in complex with unstructured MBP binding site d
Descriptor: Maltose-binding periplasmic protein, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
6PQ2
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BU of 6pq2 by Molmil
Structural Basis for Client Recognition and Activity of Hsp40 Chaperones
Descriptor: Alkaline phosphatase,Chaperone DnaJ domain-containing protein fusion
Authors:Jiang, Y, Rossi, P, Kalodimos, C.G.
Deposit date:2019-07-08
Release date:2019-09-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for client recognition and activity of Hsp40 chaperones.
Science, 365, 2019
6PQM
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BU of 6pqm by Molmil
Structural Basis for Client Recognition and Activity of Hsp40 Chaperones
Descriptor: Alkaline phosphatase,Chaperone protein DnaJ 2 fusion
Authors:Jiang, Y, Rossi, P, Kalodimos, C.G.
Deposit date:2019-07-09
Release date:2019-09-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for client recognition and activity of Hsp40 chaperones.
Science, 365, 2019
5JTP
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BU of 5jtp by Molmil
The structure of chaperone SecB in complex with unstructured proPhoA binding site e
Descriptor: Alkaline phosphatase, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTO
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BU of 5jto by Molmil
The structure of chaperone SecB in complex with unstructured proPhoA binding site d
Descriptor: Alkaline phosphatase, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016
5JTR
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BU of 5jtr by Molmil
The structure of chaperone SecB in complex with unstructured MBP binding site e
Descriptor: Maltose-binding periplasmic protein, Protein-export protein SecB
Authors:Huang, C, Saio, T, Rossi, P, Kalodimos, C.G.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the antifolding activity of a molecular chaperone.
Nature, 537, 2016

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