7OCH
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![BU of 7och by Molmil](/molmil-images/mine/7och) | Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-04-26 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OE3
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![BU of 7oe3 by Molmil](/molmil-images/mine/7oe3) | Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO] | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-01 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OEB
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![BU of 7oeb by Molmil](/molmil-images/mine/7oeb) | Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO] | Descriptor: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-02 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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1Y64
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![BU of 1y64 by Molmil](/molmil-images/mine/1y64) | Bni1p Formin Homology 2 Domain complexed with ATP-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Otomo, T, Tomchick, D.R, Otomo, C, Panchal, S.C, Machius, M, Rosen, M.K. | Deposit date: | 2004-12-03 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain Nature, 433, 2005
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8CI5
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![BU of 8ci5 by Molmil](/molmil-images/mine/8ci5) | Structure of the SNV L protein bound to 5' RNA | Descriptor: | RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L | Authors: | Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | Deposit date: | 2023-02-08 | Release date: | 2023-07-19 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional characterization of the Sin Nombre virus L protein. Plos Pathog., 19, 2023
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7OJN
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![BU of 7ojn by Molmil](/molmil-images/mine/7ojn) | Lassa virus L protein in an elongation conformation [ELONGATION] | Descriptor: | 3' RNA, 5' RNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-16 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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4V62
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![BU of 4v62 by Molmil](/molmil-images/mine/4v62) | Crystal Structure of cyanobacterial Photosystem II | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Guskov, A, Gabdulkhakov, A, Kern, J, Broser, M, Zouni, A, Saenger, W. | Deposit date: | 2008-01-17 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride Nat.Struct.Mol.Biol., 16, 2009
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4V82
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![BU of 4v82 by Molmil](/molmil-images/mine/4v82) | Crystal structure of cyanobacterial Photosystem II in complex with terbutryn | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Gabdulkhakov, A, Broser, M, Guskov, A, Kern, J, Glockner, C, Muh, F, Saenger, W, Zouni, A. | Deposit date: | 2010-11-30 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn J.Biol.Chem., 286, 2011
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7MF0
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![BU of 7mf0 by Molmil](/molmil-images/mine/7mf0) | Co-crystal structure of PERK with inhibitor (R)-2-amino-N-cyclopropyl-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)nicotinamide | Descriptor: | 2-amino-N-cyclopropyl-5-(4-{[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino}-2-methylphenyl)pyridine-3-carboxamide, Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3 | Authors: | Wiens, B, Koszelak-Rosenblum, M, Surman, M.D, Zhu, G, Mulvihill, M.J. | Deposit date: | 2021-04-08 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.809 Å) | Cite: | Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors. Bioorg.Med.Chem.Lett., 43, 2021
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7OJK
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![BU of 7ojk by Molmil](/molmil-images/mine/7ojk) | Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] | Descriptor: | 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ... | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-16 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJJ
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![BU of 7ojj by Molmil](/molmil-images/mine/7ojj) | Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-16 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJL
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![BU of 7ojl by Molmil](/molmil-images/mine/7ojl) | Lassa virus L protein in a pre-initiation conformation [PREINITIATION] | Descriptor: | 3' RNA, 5' RNA, MANGANESE (II) ION, ... | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-16 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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4ZR1
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![BU of 4zr1 by Molmil](/molmil-images/mine/4zr1) | Hydroxylase domain of scs7p | Descriptor: | Ceramide very long chain fatty acid hydroxylase SCS7, TRIDECANE, ZINC ION, ... | Authors: | Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G, Membrane Protein Structural Biology Consortium (MPSBC) | Deposit date: | 2015-05-11 | Release date: | 2015-07-29 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6008 Å) | Cite: | The Crystal Structure of an Integral Membrane Fatty Acid alpha-Hydroxylase. J.Biol.Chem., 290, 2015
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8Z4G
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![BU of 8z4g by Molmil](/molmil-images/mine/8z4g) | Structure of the S-ring region of the Vibrio flagellar MS-ring protein FliF with 35-fold symmetry applied | Descriptor: | Flagellar M-ring protein,Flagellar motor switch protein FliG | Authors: | Takekawa, N, Nishikino, T, Kishikawa, J, Hirose, M, Kato, T, Imada, K, Homma, M. | Deposit date: | 2024-04-17 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motors To Be Published
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8Z4D
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![BU of 8z4d by Molmil](/molmil-images/mine/8z4d) | Structure of the S-ring region of the Vibrio flagellar MS-ring protein FliF with 34-fold symmetry applied | Descriptor: | Flagellar M-ring protein,Flagellar motor switch protein FliG | Authors: | Takekawa, N, Nishikino, T, Kishikawa, J, Hirose, M, Kato, T, Imada, K, Homma, M. | Deposit date: | 2024-04-17 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motors To Be Published
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4ZR0
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![BU of 4zr0 by Molmil](/molmil-images/mine/4zr0) | |
4IL3
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![BU of 4il3 by Molmil](/molmil-images/mine/4il3) | Crystal Structure of S. mikatae Ste24p | Descriptor: | Ste24p, ZINC ION | Authors: | Pryor Jr, E.E, Horanyi, P.S, Clark, K, Fedoriw, N, Connelly, S.M, Koszelak-Rosenblum, M, Zhu, G, Malkowski, M.G, Dumont, M.E, Wiener, M.C, Membrane Protein Structural Biology Consortium (MPSBC) | Deposit date: | 2012-12-28 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structure of the integral membrane protein CAAX protease Ste24p. Science, 339, 2013
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3K8G
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![BU of 3k8g by Molmil](/molmil-images/mine/3k8g) | Structure of crystal form I of TP0453 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 30kLP | Authors: | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | Deposit date: | 2009-10-14 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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3K8I
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![BU of 3k8i by Molmil](/molmil-images/mine/3k8i) | Structure of crystal form IV of TP0453 | Descriptor: | 30kLP | Authors: | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | Deposit date: | 2009-10-14 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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3K8H
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![BU of 3k8h by Molmil](/molmil-images/mine/3k8h) | Structure of crystal form I of TP0453 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 30kLP | Authors: | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | Deposit date: | 2009-10-14 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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3K8J
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![BU of 3k8j by Molmil](/molmil-images/mine/3k8j) | Structure of crystal form III of TP0453 | Descriptor: | 30kLP | Authors: | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | Deposit date: | 2009-10-14 | Release date: | 2010-10-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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6Q88
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![BU of 6q88 by Molmil](/molmil-images/mine/6q88) | RT structure of HEWL at 5 kGy | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C | Authors: | de la Mora, E, Coquelle, N, Bury, C.S, Rosenthal, M, Garman, E.F, Burghammer, M, Colletier, J.P, Weik, M. | Deposit date: | 2018-12-14 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.74007058 Å) | Cite: | Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures. Proc.Natl.Acad.Sci.USA, 117, 2020
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4HHR
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![BU of 4hhr by Molmil](/molmil-images/mine/4hhr) | Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana) | Descriptor: | Alpha-dioxygenase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Goulah, C.C, Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | Deposit date: | 2012-10-10 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The crystal structure of alpha-Dioxygenase provides insight into diversity in the cyclooxygenase-peroxidase superfamily. Biochemistry, 52, 2013
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4HHS
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![BU of 4hhs by Molmil](/molmil-images/mine/4hhs) | Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana) | Descriptor: | Alpha-dioxygenase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Goulah, C.C, Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | Deposit date: | 2012-10-10 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of alpha-Dioxygenase provides insight into diversity in the cyclooxygenase-peroxidase superfamily. Biochemistry, 52, 2013
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8GQY
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![BU of 8gqy by Molmil](/molmil-images/mine/8gqy) | CryoEM structure of pentameric MotA from Aquifex aeolicus | Descriptor: | Motility protein A | Authors: | Nishikino, T, Takekawa, N, Kishikawa, J, Hirose, M, Onoe, S, Kato, T, Imada, K. | Deposit date: | 2022-08-31 | Release date: | 2022-10-26 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of MotA, a flagellar stator protein, from hyperthermophile. Biochem.Biophys.Res.Commun., 631, 2022
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