1IX2
 
 | | Crystal Structure of Selenomethionine PcoC, a Copper Resistance Protein from Escherichia coli | | Descriptor: | PcoC copper resistance protein | | Authors: | Wernimont, A.K, Huffman, D.L, Finney, L.A, Demeler, B, O'Halloran, T.V, Rosenzweig, A.C. | | Deposit date: | 2002-06-10 | | Release date: | 2002-11-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli
J.BIOL.INORG.CHEM., 8, 2003
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3SDM
 | | Structure of oligomeric kinase/RNase Ire1 in complex with an oligonucleotide | | Descriptor: | Serine/threonine-protein kinase/endoribonuclease IRE1 | | Authors: | Korennykh, A, Korostelev, A, Egea, P, Finer-Moore, J, Zhang, C, Stroud, R, Shokat, K, Walter, P. | | Deposit date: | 2011-06-09 | | Release date: | 2011-07-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (6.6 Å) | | Cite: | Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1.
Bmc Biol., 9, 2011
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1TL4
 | | Solution structure of Cu(I) HAH1 | | Descriptor: | COPPER (I) ION, Copper transport protein ATOX1 | | Authors: | Anastassopoulou, I, Banci, L, Bertini, I, Cantini, F, Katsari, E, Rosato, A, Structural Proteomics in Europe (SPINE) | | Deposit date: | 2004-06-09 | | Release date: | 2004-10-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Apo and Copper(I)-Loaded Human Metallochaperone HAH1.
Biochemistry, 43, 2004
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3FS6
 | | Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes | | Descriptor: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A. | | Deposit date: | 2009-01-09 | | Release date: | 2009-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
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4OJ8
 | | Crystal structure of carbapenem synthase in complex with (3S,5S)-carbapenam | | Descriptor: | (2S,5S)-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5R)-carbapenem-3-carboxylate synthase, 2-OXOGLUTARIC ACID, ... | | Authors: | Boal, A.K, Rosenzweig, A.C. | | Deposit date: | 2014-01-20 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.
Science, 343, 2014
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1PIU
 | | OXIDIZED RIBONUCLEOTIDE REDUCTASE R2-D84E MUTANT CONTAINING OXO-BRIDGED DIFERRIC CLUSTER | | Descriptor: | FE (III) ION, MERCURY (II) ION, OXYGEN ATOM, ... | | Authors: | Voegtli, W.C, Khidekel, N, Baldwin, J, Ley, B.A, Bollinger Jr, J.M, Rosenzweig, A.C. | | Deposit date: | 2003-05-30 | | Release date: | 2003-06-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of the Ribonucleotide Reductase R2 Mutant that Accumulates a u-1,2-Peroxodiiron(III)
Intermediate during Oxygen Activation
J.Am.Chem.Soc., 122, 2000
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2X2Y
 | | Cellulomonas fimi endo-beta-1,4-mannanase double mutant | | Descriptor: | FORMIC ACID, MAGNESIUM ION, MAN26A | | Authors: | Hekmat, O, Lo Leggio, L, Rosengren, A, Kamarauskaite, J, Kolenova, K, Staalbrand, H. | | Deposit date: | 2010-01-18 | | Release date: | 2010-06-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Rational Engineering of Mannosyl Binding in the Distal Glycone Subsites of Cellulomonas Fimi Endo-Beta-1,4-Mannanase: Mannosyl Binding Promoted at Subsite -2 and Demoted at Subsite -3 .
Biochemistry, 49, 2010
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3TJK
 | | Crystal Structure of human peroxiredoxin IV C245A mutant in reduced form | | Descriptor: | Peroxiredoxin-4 | | Authors: | Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. | | Deposit date: | 2011-08-24 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle.
J.Biol.Chem., 286, 2011
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3RFA
 | | X-ray structure of RlmN from Escherichia coli in complex with S-adenosylmethionine | | Descriptor: | IRON/SULFUR CLUSTER, Ribosomal RNA large subunit methyltransferase N, S-ADENOSYLMETHIONINE | | Authors: | Boal, A.K, Grove, T.L, McLaughlin, M.I, Yennawar, N, Booker, S.J, Rosenzweig, A.C. | | Deposit date: | 2011-04-05 | | Release date: | 2011-05-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
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3RJ6
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4TQ8
 | | Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR) | | Descriptor: | 1,2-ETHANEDIOL, 3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid, Transthyretin | | Authors: | Ciccone, L, Orlandini, E, Nencetti, S, Rossello, A, Stura, E.A. | | Deposit date: | 2014-06-10 | | Release date: | 2015-06-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
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1QUP
 | | CRYSTAL STRUCTURE OF THE COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE | | Descriptor: | SULFATE ION, SUPEROXIDE DISMUTASE 1 COPPER CHAPERONE | | Authors: | Lamb, A.L, Wernimont, A.K, Pufahl, R.A, O'Halloran, T.V, Rosenzweig, A.C. | | Deposit date: | 1999-07-01 | | Release date: | 1999-12-10 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the copper chaperone for superoxide dismutase.
Nat.Struct.Biol., 6, 1999
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3TJG
 | | Crystal Structure of human peroxiredoxin IV C51A mutant in oxidized form | | Descriptor: | Peroxiredoxin-4 | | Authors: | Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. | | Deposit date: | 2011-08-24 | | Release date: | 2011-10-12 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle.
J.Biol.Chem., 286, 2011
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1LYQ
 | | Crystal Structure of PcoC, a Methionine Rich Copper Resistance Protein from Escherichia coli | | Descriptor: | GLYCEROL, PcoC copper resistance protein | | Authors: | Wernimont, A.K, Huffman, D.L, Finney, L.A, Demeler, B, O'Halloran, T.V, Rosenzweig, A.C. | | Deposit date: | 2002-06-07 | | Release date: | 2002-11-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli
J.BIOL.INORG.CHEM., 8, 2003
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3QAC
 | | Structure of amaranth 11S proglobulin seed storage protein from Amaranthus hypochondriacus L. | | Descriptor: | 11S globulin seed storage protein | | Authors: | Tandang-Silvas, M.R, Carrazco-Pena, L, Barba de la Rosa, A.P, Osuna-Castro, J.A, Utsumi, S, Mikami, B, Maruyama, N. | | Deposit date: | 2011-01-10 | | Release date: | 2012-01-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.275 Å) | | Cite: | Structure of amaranth 11S proglobulin, a major seed storage protein from Amaranthus hypochondriacus L.
To be Published
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1W5X
 | | HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor | | Descriptor: | (2R,3R,4R,5R)-2,5-BIS[(2,3-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXAN EDIAMIDE, POL POLYPROTEIN | | Authors: | Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. | | Deposit date: | 2004-08-10 | | Release date: | 2004-12-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
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6P1E
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4TQH
 | | Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid | | Descriptor: | 1,2-ETHANEDIOL, Transthyretin, [(9H-fluoren-9-ylideneamino)oxy]acetic acid | | Authors: | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | | Deposit date: | 2014-06-11 | | Release date: | 2015-06-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.511 Å) | | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
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4TWV
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4TWU
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6PJ6
 | | High resolution cryo-EM structure of E.coli 50S | | Descriptor: | 23S rRNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | Authors: | Stojkovic, V, Myasnikov, A, Frost, A, Fujimori, D.G. | | Deposit date: | 2019-06-27 | | Release date: | 2020-01-22 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit.
Nucleic Acids Res., 48, 2020
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4PL2
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4U9R
 | | Structure of the N-terminal Extension from Cupriavidus metallidurans CzcP | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, CADMIUM ION, CzcP cation efflux P1-ATPase | | Authors: | Smith, A.T, Rosenzweig, A.C. | | Deposit date: | 2014-08-06 | | Release date: | 2015-07-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | A new metal binding domain involved in cadmium, cobalt and zinc transport.
Nat.Chem.Biol., 11, 2015
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2C7E
 | | REVISED ATOMIC STRUCTURE FITTING INTO A GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047) | | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | | Deposit date: | 2005-11-22 | | Release date: | 2006-02-16 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (14.9 Å) | | Cite: | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy
Cell(Cambridge,Mass.), 107, 2001
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3F8Z
 | | Human Dihydrofolate Reductase Structural Data with Active Site Mutant Enzyme Complexes | | Descriptor: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A. | | Deposit date: | 2008-11-13 | | Release date: | 2009-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
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