4OJ8
Crystal structure of carbapenem synthase in complex with (3S,5S)-carbapenam
Summary for 4OJ8
Entry DOI | 10.2210/pdb4oj8/pdb |
Descriptor | (5R)-carbapenem-3-carboxylate synthase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total) |
Functional Keywords | oxidoreductase, oxygenase, iron, 2-oxoglutaric acid, antibiotic biosynthesis, carbapenam |
Biological source | Pectobacterium carotovorum subsp. carotovorum |
Cellular location | Cytoplasm : Q9XB59 |
Total number of polymer chains | 3 |
Total formula weight | 102471.87 |
Authors | Boal, A.K.,Rosenzweig, A.C. (deposition date: 2014-01-20, release date: 2014-04-02, Last modification date: 2023-09-20) |
Primary citation | Chang, W.C.,Guo, Y.,Wang, C.,Butch, S.E.,Rosenzweig, A.C.,Boal, A.K.,Krebs, C.,Bollinger, J.M. Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics. Science, 343:1140-1144, 2014 Cited by PubMed: 24604200DOI: 10.1126/science.1248000 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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