7Q98
 
 | | MHC Class I A02 Allele presenting NLSALGIFST | | 分子名称: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | | 著者 | Rizkallah, P.J, Sewell, A.K. | | 登録日 | 2021-11-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
|
|
7Q9A
 | | MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | | 分子名称: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | 登録日 | 2021-11-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
|
|
6I25
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phosphono-D-ribitol, Aureochrome1-like protein, CHLORIDE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E. | | 登録日 | 2018-10-31 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6I20
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6I22
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | Aureochrome1-like protein, FLAVIN MONONUCLEOTIDE | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6I21
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, Aureochrome1-like protein, CHLORIDE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6I24
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phosphono-D-ribitol, ACETATE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6I23
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phosphono-D-ribitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
|
|
6SS9
 | | Human Leukocyte Antigen Class I A02 Carrying LLWNGPMHV | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Rizkallah, P.J, Bovay, A. | | 登録日 | 2019-09-06 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
|
|
6SM0
 | | Venus 66 p-Azido-L-Phenylalanin (azF) variant, dark grown | | 分子名称: | Green fluorescent protein, OXYGEN MOLECULE, SULFATE ION, ... | | 著者 | Rizkallah, P.J, Al Maslookhi, H.S, Jones, D.D. | | 登録日 | 2019-08-21 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step.
Chem Sci, 12, 2021
|
|
6R2L
 | | NYBR1-A2-SLSKILDTV | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ... | | 著者 | Rizkallah, P.J, Cole, D.K, Sami, M. | | 登録日 | 2019-03-18 | | 公開日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | NYBR1-A2-SLSKILDTV
To Be Published
|
|
6SS8
 | | Human Leukocyte Antigen Class I A02 Carrying LLWNGPIAV | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Beta-2-microglobulin, ... | | 著者 | Rizkallah, P.J, Bovay, A. | | 登録日 | 2019-09-06 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
|
|
6SMS
 | | Vegetative Insecticidal Protein 1 (Vip1Ac1) from Bacillus thuringiensis | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SULFATE ION, ... | | 著者 | Rizkallah, P.J, Al-Maslookhi, H.S, Berry, C, Jones, D. | | 登録日 | 2019-08-22 | | 公開日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Bacillus thuringiensis insecticidal protein 1Ac, VIP1Ac
Not Published
|
|
6SSA
 | |
6SS7
 | |
6TMO
 | | Structure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting a MART-1 peptide, EAAGIGILTV | | 分子名称: | 1,2-ETHANEDIOL, Alpha chain of engineered high affinity T-cell receptor, Beta chain of high affinity engineered T-cell receptor, ... | | 著者 | Rizkallah, P.J, Cole, D.K. | | 登録日 | 2019-12-05 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy.
Mol Ther Oncolytics, 18, 2020
|
|
5HYJ
 | | 1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA | | 分子名称: | ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | | 登録日 | 2016-02-01 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126, 2016
|
|
3DZW
 | |
6EQB
 | | HLA class I histocompatibility antigen | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | | 著者 | Rizkallah, P.J, Cole, D.K. | | 登録日 | 2017-10-12 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | TCR-induced alteration of primary MHC peptide anchor residue.
Eur.J.Immunol., 49, 2019
|
|
2F53
 | | Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity | | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ... | | 著者 | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | | 登録日 | 2005-11-25 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
|
|
2HP4
 | | Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor | | 分子名称: | GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain | | 著者 | Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F. | | 登録日 | 2006-07-17 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
|
|
4WDI
 | |
2BCK
 | | Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F. | | 登録日 | 2005-10-19 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
|
|
2F54
 | | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity | | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1B, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | | 登録日 | 2005-11-25 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
|
|
7OP2
 | | Chadox1/ Chimpanzee adenovirus Y25 fiber knob protein | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Rizkallah, P.J, Baker, A.T, Parker, A.L, Teijeira Crespo, A, Lipka-Lloyd, M. | | 登録日 | 2021-05-28 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
Sci Adv, 7, 2021
|
|
