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PDB: 8 件

3FS1
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Crystal structure of HNF4a LBD in complex with the ligand and the coactivator PGC-1a fragment
分子名称: Hepatocyte nuclear factor 4-alpha, MYRISTIC ACID, PPARgamma Coactivator-1a (PGC-1a)
著者Rha, G, Wu, G, Chi, Y.
登録日2009-01-08
公開日2009-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation
J.Biol.Chem., 284, 2009
3CBB
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Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
分子名称: Hepatocyte Nuclear Factor 4-alpha promoter element DNA, Hepatocyte Nuclear Factor 4-alpha, DNA binding domain, ...
著者Lu, P, Rha, G.B, Melikishvili, M, Adkins, B.C, Fried, M.G, Chi, Y.I.
登録日2008-02-21
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product.
J.Biol.Chem., 283, 2008
2H8R
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Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product
分子名称: 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*G)-3', 5'-D(*GP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3', Hepatocyte nuclear factor 1-beta
著者Lu, P, Rha, G.B, Chi, Y.I.
登録日2006-06-07
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta.
Biochemistry, 46, 2007
1UOB
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Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and penicillin G
分子名称: 2-OXOGLUTARIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHETASE, FE (II) ION, ...
著者Valegard, K, Terwisscha van Scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I.
登録日2003-09-16
公開日2004-01-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme
Nat.Struct.Mol.Biol., 11, 2004
1UOF
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Deacetoxycephalosporin C synthase complexed with Penicillin G
分子名称: DEACETOXYCEPHALOSPORIN C SYNTHETASE, FE (II) ION, PENICILLIN G
著者Valegard, K, Terwisscha Van scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I.
登録日2003-09-16
公開日2004-01-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme
Nat.Struct.Mol.Biol., 11, 2004
1UO9
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Deacetoxycephalosporin C synthase complexed with succinate
分子名称: DEACETOXYCEPHALOSPORIN C SYNTHETASE, FE (II) ION, SUCCINIC ACID
著者Valegard, K, Terwisscha Van scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I.
登録日2003-09-16
公開日2004-01-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme
Nat.Struct.Mol.Biol., 11, 2004
1UNB
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Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and ampicillin
分子名称: (2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, 2-OXOGLUTARIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHETASE, ...
著者Valegard, K, Terwisscha van Scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I.
登録日2003-09-09
公開日2004-01-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme
Nat.Struct.Mol.Biol., 11, 2004
1UOG
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Deacetoxycephalosporin C synthase complexed with deacetoxycephalosporin C
分子名称: DEACETOXYCEPHALOSPORIN C SYNTHETASE, DEACETOXYCEPHALOSPORIN-C, FE (II) ION
著者Valegard, K, Terwisscha van Scheltinga, A.C, Dubus, A, Oster, L.M, Rhangino, G, Hajdu, J, Andersson, I.
登録日2003-09-17
公開日2004-01-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structural Basis of Cephalosporin Formation in a Mononuclear Ferrous Enzyme
Nat.Struct.Mol.Biol., 11, 2004

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