4IXN
| Crystal Structure of Zn(II)-bound E37A,C66A,C67A triple mutant YjiA GTPase | Descriptor: | SULFATE ION, Uncharacterized GTP-binding protein YjiA, ZINC ION | Authors: | Jost, M, Drennan, C.L. | Deposit date: | 2013-01-26 | Release date: | 2013-02-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases. Biochemistry, 52, 2013
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6CIN
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5T8Y
| Structure of epoxyqueuosine reductase from Bacillus subtilis with the Asp134 catalytic loop swung out of the active site. | Descriptor: | COBALAMIN, Epoxyqueuosine reductase, IRON/SULFUR CLUSTER, ... | Authors: | Dowling, D.P, Miles, Z.D, Kohrer, C, Maiocco, S.J, Elliott, S.J, Bandarian, V, Drennan, C.L. | Deposit date: | 2016-09-08 | Release date: | 2016-09-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.653 Å) | Cite: | Molecular basis of cobalamin-dependent RNA modification. Nucleic Acids Res., 44, 2016
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4ERP
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2HZA
| Nickel-bound full-length Escherichia coli NikR | Descriptor: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, NICKEL (II) ION, Nickel-responsive regulator | Authors: | Schreiter, E.R, Drennan, C.L. | Deposit date: | 2006-08-08 | Release date: | 2006-08-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | NikR-operator complex structure and the mechanism of repressor activation by metal ions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1R30
| The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Biotin synthase, ... | Authors: | Berkovitch, F, Nicolet, Y, Wan, J.T, Jarrett, J.T, Drennan, C.L. | Deposit date: | 2003-09-30 | Release date: | 2004-01-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme. Science, 303, 2004
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6X5K
| Crystal structure of CODH/ACS with carbon monoxide bound to the A-cluster | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CARBON MONOXIDE, Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, ... | Authors: | Cohen, S.E, Wittenborn, E.C, Hendrickson, R, Drennan, C.L. | Deposit date: | 2020-05-26 | Release date: | 2020-10-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Acs Catalysis, 10, 2020
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4K39
| Native anSMEcpe with bound AdoMet and Cp18Cys peptide | Descriptor: | Anaerobic sulfatase-maturating enzyme, CHLORIDE ION, Cp18Cys peptide, ... | Authors: | Goldman, P.J, Drennan, C.L. | Deposit date: | 2013-04-10 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification. Proc.Natl.Acad.Sci.USA, 110, 2013
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5EXJ
| Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase | Authors: | McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L. | Deposit date: | 2015-11-23 | Release date: | 2016-08-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystallographic snapshots of sulfur insertion by lipoyl synthase. Proc.Natl.Acad.Sci.USA, 113, 2016
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4EIQ
| Chromopyrrolic acid-soaked RebC-10x with bound 7-carboxy-K252c | Descriptor: | (5S)-7-oxo-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5-carboxylic acid, Putative FAD-monooxygenase | Authors: | Goldman, P.J, Ryan, K.S, Howard-Jones, A.R, Hamill, M.J, Elliott, S.J, Walsh, C.T, Drennan, C.L. | Deposit date: | 2012-04-05 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes. Chem.Biol., 19, 2012
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7LHR
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7LHU
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5EXI
| Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, IRON/SULFUR CLUSTER, Lipoyl synthase | Authors: | McLaughlin, M.I, Lanz, N.D, Goldman, P.J, Lee, K.-H, Booker, S.J, Drennan, C.L. | Deposit date: | 2015-11-23 | Release date: | 2016-08-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystallographic snapshots of sulfur insertion by lipoyl synthase. Proc.Natl.Acad.Sci.USA, 113, 2016
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2FCV
| SyrB2 with Fe(II), bromide, and alpha-ketoglutarate | Descriptor: | ((2R,3S,4S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-5-((2R,3S,4S,5S,6R)-3,4,5-TRIHYDROXY-6-METHOXY-TETRAHYDRO-2H-PYRAN-2-YLOXY)-TETRAHYDROFURAN-2-YL)METHYL NONANOATE, 2-OXOGLUTARIC ACID, BROMIDE ION, ... | Authors: | Blasiak, L.C, Drennan, C.L. | Deposit date: | 2005-12-12 | Release date: | 2006-03-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature, 440, 2006
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2FCT
| SyrB2 with Fe(II), chloride, and alpha-ketoglutarate | Descriptor: | ((2R,3S,4S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-5-((2R,3S,4S,5S,6R)-3,4,5-TRIHYDROXY-6-METHOXY-TETRAHYDRO-2H-PYRAN-2-YLOXY)-TETRAHYDROFURAN-2-YL)METHYL NONANOATE, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Blasiak, L.C, Drennan, C.L. | Deposit date: | 2005-12-12 | Release date: | 2006-03-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature, 440, 2006
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2FCU
| SyrB2 with alpha-ketoglutarate | Descriptor: | ((2R,3S,4S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-5-((2R,3S,4S,5S,6R)-3,4,5-TRIHYDROXY-6-METHOXY-TETRAHYDRO-2H-PYRAN-2-YLOXY)-TETRAHYDROFURAN-2-YL)METHYL NONANOATE, 2-OXOGLUTARIC ACID, syringomycin biosynthesis enzyme 2 | Authors: | Blasiak, L.C, Drennan, C.L. | Deposit date: | 2005-12-12 | Release date: | 2006-03-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature, 440, 2006
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3C8F
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3GJA
| CytC3 | Descriptor: | ACETATE ION, CytC3 | Authors: | Wong, C, Drennan, C.L. | Deposit date: | 2009-03-08 | Release date: | 2009-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of an open active site conformation of nonheme iron halogenase CytC3 J.Am.Chem.Soc., 131, 2009
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4ERM
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6B6W
| Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 2), oxidized C-cluster | Descriptor: | CHLORIDE ION, Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, ... | Authors: | Wittenborn, E.C, Drennan, C.L. | Deposit date: | 2017-10-03 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
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6B6V
| Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 1), canonical C-cluster | Descriptor: | Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Wittenborn, E.C, Drennan, C.L. | Deposit date: | 2017-10-03 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
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5TH5
| Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound | Descriptor: | 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | Authors: | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | Deposit date: | 2016-09-29 | Release date: | 2017-01-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.407 Å) | Cite: | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies. J. Am. Chem. Soc., 139, 2017
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6UQN
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6B6Y
| Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, dithionite-reduced then oxygen-exposed (protein batch 2), oxidized C-cluster | Descriptor: | Carbon monoxide dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, Fe(4)-Ni(1)-S(4) cluster, ... | Authors: | Wittenborn, E.C, Drennan, C.L. | Deposit date: | 2017-10-03 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
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6B9R
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