4L27
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![BU of 4l27 by Molmil](/molmil-images/mine/4l27) | Crystal structure of delta1-39 and delta516-525 human cystathionine beta-synthase D444N mutant containing C-terminal 6xHis tag | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez, L.A. | Deposit date: | 2013-06-04 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.391 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L3V
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![BU of 4l3v by Molmil](/molmil-images/mine/4l3v) | Crystal structure of delta516-525 human cystathionine beta-synthase | Descriptor: | Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez, L.A. | Deposit date: | 2013-06-07 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.628 Å) | Cite: | Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
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3NNK
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![BU of 3nnk by Molmil](/molmil-images/mine/3nnk) | |
3O7J
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![BU of 3o7j by Molmil](/molmil-images/mine/3o7j) | |
3O7K
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![BU of 3o7k by Molmil](/molmil-images/mine/3o7k) | |
3QVK
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![BU of 3qvk by Molmil](/molmil-images/mine/3qvk) | Allantoin racemase from Klebsiella pneumoniae | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Putative hydantoin racemase | Authors: | French, J.B, Neau, D.B, Ealick, S.E. | Deposit date: | 2011-02-25 | Release date: | 2011-05-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase. J.Mol.Biol., 410, 2011
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3QVJ
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![BU of 3qvj by Molmil](/molmil-images/mine/3qvj) | |
3QVL
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![BU of 3qvl by Molmil](/molmil-images/mine/3qvl) | Allantoin racemase from Klebsiella pneumoniae | Descriptor: | Putative hydantoin racemase, [(4R)-2,5-dioxoimidazolidin-4-yl]acetic acid | Authors: | French, J.B, Neau, D.B, Ealick, S.E. | Deposit date: | 2011-02-25 | Release date: | 2011-05-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.822 Å) | Cite: | Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase. J.Mol.Biol., 410, 2011
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3O91
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![BU of 3o91 by Molmil](/molmil-images/mine/3o91) | High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes | Descriptor: | ZINC ION, nicotinamidase | Authors: | French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. | Deposit date: | 2010-08-03 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
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3O90
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![BU of 3o90 by Molmil](/molmil-images/mine/3o90) | High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes | Descriptor: | ZINC ION, nicotinamidase | Authors: | French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. | Deposit date: | 2010-08-03 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
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3BJI
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![BU of 3bji by Molmil](/molmil-images/mine/3bji) | Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 | Descriptor: | Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION | Authors: | Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | Deposit date: | 2007-12-04 | Release date: | 2008-07-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
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3O92
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![BU of 3o92 by Molmil](/molmil-images/mine/3o92) | High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes | Descriptor: | ZINC ION, nicotinamidase | Authors: | French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. | Deposit date: | 2010-08-03 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
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3O93
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![BU of 3o93 by Molmil](/molmil-images/mine/3o93) | High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes | Descriptor: | ZINC ION, nicotinamidase | Authors: | French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. | Deposit date: | 2010-08-03 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
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3O94
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![BU of 3o94 by Molmil](/molmil-images/mine/3o94) | High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes | Descriptor: | NICOTINAMIDE, ZINC ION, nicotinamidase | Authors: | French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. | Deposit date: | 2010-08-03 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
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3EQB
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![BU of 3eqb by Molmil](/molmil-images/mine/3eqb) | X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... | Authors: | Ohren, J.F, Pavlovsky, A, Zhang, E. | Deposit date: | 2008-09-30 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | 2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase). Bioorg.Med.Chem.Lett., 18, 2008
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3VU0
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![BU of 3vu0 by Molmil](/molmil-images/mine/3vu0) | Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (AfAglB-S2, AF_0040, O30195_ARCFU) from Archaeoglobus fulgidus | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein | Authors: | Nyirenda, J, Matsumoto, S, Saitoh, T, Maita, N, Noda, N.N, Inagaki, F, Kohda, D. | Deposit date: | 2012-06-13 | Release date: | 2013-01-23 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystallographic and NMR Evidence for Flexibility in Oligosaccharyltransferases and Its Catalytic Significance Structure, 21, 2013
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3VU1
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![BU of 3vu1 by Molmil](/molmil-images/mine/3vu1) | Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (PhAglB-L, O74088_PYRHO) from Pyrococcus horikoshii | Descriptor: | CALCIUM ION, CHLORIDE ION, Putative uncharacterized protein PH0242 | Authors: | Nyirenda, J, Matsumoto, S, Saitoh, T, Maita, N, Noda, N.N, Inagaki, F, Kohda, D. | Deposit date: | 2012-06-13 | Release date: | 2013-01-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystallographic and NMR Evidence for Flexibility in Oligosaccharyltransferases and Its Catalytic Significance Structure, 21, 2013
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3QVA
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2SBT
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![BU of 2sbt by Molmil](/molmil-images/mine/2sbt) | A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO | Descriptor: | ACETONE, SUBTILISIN NOVO | Authors: | Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R. | Deposit date: | 1976-09-07 | Release date: | 1976-10-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo. Cold Spring Harbor Symp.Quant.Biol., 36, 1972
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2P55
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![BU of 2p55 by Molmil](/molmil-images/mine/2p55) | |
3DY7
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![BU of 3dy7 by Molmil](/molmil-images/mine/3dy7) | X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP | Descriptor: | (5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Ohren, J.F, Pavlovsky, A, Zhang, E. | Deposit date: | 2008-07-25 | Release date: | 2009-06-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK? Bioorg.Med.Chem.Lett., 19, 2009
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3EYZ
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![BU of 3eyz by Molmil](/molmil-images/mine/3eyz) | Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA (open form) | Descriptor: | 5'-D(*DAP*DTP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DAP*DGP*DGP*DA)-3', 5'-D(*DCP*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DGP*DC)-3', DNA polymerase I, ... | Authors: | Warren, J.J, Wu, E.Y, Golosov, A.A, Karplus, M, Beese, L.S. | Deposit date: | 2008-10-22 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis. Structure, 18, 2010
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3RM5
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![BU of 3rm5 by Molmil](/molmil-images/mine/3rm5) | |
2O8C
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![BU of 2o8c by Molmil](/molmil-images/mine/2o8c) | human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair | Descriptor: | 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*(6OG)P*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. | Deposit date: | 2006-12-12 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
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2O8B
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![BU of 2o8b by Molmil](/molmil-images/mine/2o8b) | human MutSalpha (MSH2/MSH6) bound to ADP and a G T mispair | Descriptor: | 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. | Deposit date: | 2006-12-12 | Release date: | 2007-06-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
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