6Y6N
 
 | | Structure of mature activin A with small molecule 2 | | Descriptor: | (3~{R})-3,4-dimethyl-3-propyl-1~{H}-1,4-benzodiazepine-2,5-dione, Inhibin beta A chain, SULFATE ION | | Authors: | McLoughlin, J.D, Brear, P.B, Reinhardt, T, Spring, D.R, Hyvonen, M. | | Deposit date: | 2020-02-26 | | Release date: | 2021-01-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
Chem Sci, 11, 2020
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6Y6O
 | | Structure of mature activin A with small molecule 42 | | Descriptor: | (3~{R})-4-ethyl-3-methyl-3-propyl-1~{H}-1,4-benzodiazepine-2,5-dione, Inhibin beta A chain, SULFATE ION | | Authors: | McLoughlin, J.D, Brear, P.B, Reinhardt, T, Spring, D.R, Hyvonen, M. | | Deposit date: | 2020-02-26 | | Release date: | 2021-02-03 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
Chem Sci, 11, 2020
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9F65
 | | Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori) | | Descriptor: | 3-methyl-2-(prop-2-ynoxymethyl)imidazol-4-amine, Thiol peroxidase | | Authors: | Fiedler, M.K, Gong, R, Fuchs, S, Rox, K, Friedrich, V, Pfeiffer, D, Reinhardt, T, Mibus, C, Huber, M, Hess, C, Mejias-Luque, R, Gerhard, M, Groll, M, Sieber, S.A. | | Deposit date: | 2024-04-30 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | 5-Nitroimidazole ethers boost anti-Helicobacter pylori activity via a dual mode of action and effectively eradicate infections in vivo
to be published
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9F5V
 | | Crystal structure of thiol peroxidase from Helicobacter pylori (HpTx, reduced) | | Descriptor: | Thiol peroxidase | | Authors: | Fiedler, M.K, Gong, R, Fuchs, S, Rox, K, Friedrich, V, Pfeiffer, D, Reinhardt, T, Mibus, C, Huber, M, Hess, C, Mejias-Luque, R, Gerhard, M, Groll, M, Sieber, S.A. | | Deposit date: | 2024-04-30 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | 5-Nitroimidazole ethers boost anti-Helicobacter pylori activity via a dual mode of action and effectively eradicate infections in vivo
to be published
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9F64
 | | Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro* (H. pylori | | Descriptor: | 1,2-ETHANEDIOL, 2-(5-azanyl-2-methyl-imidazol-1-yl)ethanol, SODIUM ION, ... | | Authors: | Fiedler, M.K, Gong, R, Fuchs, S, Rox, K, Friedrich, V, Pfeiffer, D, Reinhardt, T, Mibus, C, Huber, M, Hess, C, Mejias-Luque, R, Gerhard, M, Groll, M, Sieber, S.A. | | Deposit date: | 2024-04-30 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | 5-Nitroimidazole ethers boost anti-Helicobacter pylori activity via a dual mode of action and effectively eradicate infections in vivo
to be published
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