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PDB: 149 results

6ZXJ
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BU of 6zxj by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked)
Descriptor: Lethal factor, Protective antigen
Authors:Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
Deposit date:2020-07-29
Release date:2020-09-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
4NF9
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BU of 4nf9 by Molmil
Structure of the Knl1/Nsl1 complex
Descriptor: CHLORIDE ION, Kinetochore-associated protein NSL1 homolog, Protein CASC5
Authors:Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A.
Deposit date:2013-10-31
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Mol.Cell, 53, 2014
6ZXL
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BU of 6zxl by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement
Descriptor: Lethal factor, Protective antigen
Authors:Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
Deposit date:2020-07-29
Release date:2020-09-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6SUE
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BU of 6sue by Molmil
Structure of Photorhabdus luminescens Tc holotoxin pore, Mutation TccC3-D651A
Descriptor: TcdA1, TcdB2,TccC3
Authors:Roderer, D, Raunser, S.
Deposit date:2019-09-13
Release date:2019-11-06
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of a Tc holotoxin pore provides insights into the translocation mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
7ZBQ
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BU of 7zbq by Molmil
Structure of the ADP-ribosyltransferase TccC3HVR from Photorhabdus Luminescens
Descriptor: TccC3
Authors:Lindemann, F, Belyy, A, Friedrich, D, Schmieder, P, Bardiaux, B, Roderer, D, Funk, J, Protze, J, Bieling, P, Oschkinat, H, Raunser, S.
Deposit date:2022-03-24
Release date:2022-06-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Nat Commun, 13, 2022
6H3L
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BU of 6h3l by Molmil
Structure of VgrG1 in the Type VI secretion "pre-firing" VgrG1-Tse6-EagT6-EF-Tu-Tsi6 complex
Descriptor: VgrG1
Authors:Quentin, D, Raunser, S.
Deposit date:2018-07-19
Release date:2018-09-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of loading and translocation of type VI secretion system effector Tse6.
Nat Microbiol, 3, 2018
6GY6
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BU of 6gy6 by Molmil
XaxAB pore complex from Xenorhabdus nematophila
Descriptor: XaxA, XaxB
Authors:Schubert, E, Raunser, S.
Deposit date:2018-06-28
Release date:2018-07-25
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Membrane insertion of alpha-xenorhabdolysin in near-atomic detail.
Elife, 7, 2018
4NFA
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BU of 4nfa by Molmil
Structure of the C-terminal doamin of Knl1
Descriptor: CHLORIDE ION, GLYCEROL, Protein CASC5
Authors:Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A.
Deposit date:2013-10-31
Release date:2014-03-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Mol.Cell, 53, 2014
6H3N
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BU of 6h3n by Molmil
Structure of VgrG1 in the Type VI secretion VgrG1-Tse6-EF-Tu complex embedded in lipid nanodiscs
Descriptor: VgrG1
Authors:Quentin, D, Raunser, S.
Deposit date:2018-07-19
Release date:2018-09-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Mechanism of loading and translocation of type VI secretion system effector Tse6.
Nat Microbiol, 3, 2018
7AD9
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BU of 7ad9 by Molmil
Structure of the Lifeact-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Belyy, A, Merino, F, Sitsel, O, Raunser, S.
Deposit date:2020-09-14
Release date:2020-10-28
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Lifeact-F-actin complex.
Plos Biol., 18, 2020
7PXF
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BU of 7pxf by Molmil
Ca2+ free Drosophila Slo channel
Descriptor: Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
6RW8
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BU of 6rw8 by Molmil
Cryo-EM structure of Xenorhabdus nematophila XptA1
Descriptor: A component of insecticidal toxin complex (Tc)
Authors:Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S.
Deposit date:2019-06-04
Release date:2019-10-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
6RWB
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BU of 6rwb by Molmil
Cryo-EM structure of Yersinia pseudotuberculosis TcaA-TcaB
Descriptor: Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit
Authors:Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S.
Deposit date:2019-06-04
Release date:2019-10-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
6FHL
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BU of 6fhl by Molmil
Cryo-EM structure of F-actin in complex with ADP-Pi
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2018-01-15
Release date:2018-06-13
Last modified:2018-08-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
6SUP
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BU of 6sup by Molmil
Crystal Structure of TcdB2-TccC3-Cdc42
Descriptor: MAGNESIUM ION, TcdB2,TccC3,Cell division control protein 42 homolog
Authors:Roderer, D, Schubert, E, Sitsel, O, Raunser, S.
Deposit date:2019-09-16
Release date:2019-12-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Towards the application of Tc toxins as a universal protein translocation system.
Nat Commun, 10, 2019
6RWA
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BU of 6rwa by Molmil
Cryo-EM structure of Photorhabdus luminescens TcdA4
Descriptor: TcdA4
Authors:Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S.
Deposit date:2019-06-04
Release date:2019-10-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
6SUF
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BU of 6suf by Molmil
Structure of Photorhabdus luminescens Tc holotoxin pore
Descriptor: TcdA1, TcdB2,TccC3
Authors:Roderer, D, Raunser, S.
Deposit date:2019-09-13
Release date:2019-11-06
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of a Tc holotoxin pore provides insights into the translocation mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6RW6
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BU of 6rw6 by Molmil
Cryo-EM structure of Photorhabdus luminescens TcdA1
Descriptor: TcdA1
Authors:Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S.
Deposit date:2019-06-04
Release date:2019-10-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
6RW9
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BU of 6rw9 by Molmil
Cryo-EM structure of Morganella morganii TcdA4
Descriptor: Insecticidal toxin protein TcdA4
Authors:Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S.
Deposit date:2019-06-04
Release date:2019-10-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
6SUQ
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BU of 6suq by Molmil
Crystal Structure of TcdB2-TccC3-TEV
Descriptor: TcdB2,TccC3,Genome polyprotein
Authors:Roderer, D, Schubert, E, Sitsel, O, Raunser, S.
Deposit date:2019-09-16
Release date:2019-12-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Towards the application of Tc toxins as a universal protein translocation system.
Nat Commun, 10, 2019
8ATD
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BU of 8atd by Molmil
Wild type hexamer oxalyl-CoA synthetase (OCS)
Descriptor: Oxalate--CoA ligase
Authors:Lill, P, Burgi, J, Raunser, S, Wilmanns, M, Gatsogiannis, C.
Deposit date:2022-08-23
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase.
Biol.Chem., 404, 2023
7AHN
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BU of 7ahn by Molmil
Cryo-EM structure of F-actin stabilized by cis-optoJASP-8
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pospich, S, Raunser, S.
Deposit date:2020-09-24
Release date:2021-01-27
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
7PXG
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BU of 7pxg by Molmil
Verruculogen-bound Drosophila Slo channel
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7PXE
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BU of 7pxe by Molmil
Ca2+ bound Drosophila Slo channel
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7AHQ
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BU of 7ahq by Molmil
Cryo-EM structure of F-actin stabilized by trans-optoJASP-8
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pospich, S, Raunser, S.
Deposit date:2020-09-25
Release date:2021-01-27
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021

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