8PI7
 
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) | | 分子名称: | CHLORIDE ION, Chains: E, Chains: F, ... | | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2023-06-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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3ZBS
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS | | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-11-13 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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3ZBZ
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-11-14 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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3ZBR
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with NADP | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-11-13 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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8PIA
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>T) | | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2023-06-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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6TA2
 | | Human NAMPT in complex with nicotinic acid mononucleotide and phosphate | | 分子名称: | CHLORIDE ION, GLYCEROL, NICOTINATE MONONUCLEOTIDE, ... | | 著者 | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Identification of structural determinants of NAMPT activity and substrate selectivity
To Be Published
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6TAC
 | | Human NAMPT deletion mutant in complex with nicotinamide mononucleotide, pyrophosphate, and Mg2+ | | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Identification of structural determinants of NAMPT activity and substrate selectivity
To Be Published
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6TA0
 | | Human NAMPT in complex with nicotinic acid and phosphoribosyl pyrophosphate | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GLYCEROL, NICOTINIC ACID, ... | | 著者 | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | | 登録日 | 2019-10-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Identification of structural determinants of NAMPT activity and substrate selectivity
To Be Published
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2YP0
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-10-29 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YOZ
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | | 分子名称: | 2'-O-(sulfidophosphinato)adenosine, 2,3-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, ACETATE ION, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-10-29 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YPC
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3-(SP)-Cyclic-AMPS | | 分子名称: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxidanyl-2-sulfanylidene-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YPE
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3'- cyclic AMP | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2',3'- cyclic AMP, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YQ9
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMP | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, ADENOSINE-2'-MONOPHOSPHATE | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-11-07 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YPH
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with 2',3-(RP)- cyclic-AMPS | | 分子名称: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, ACETATE ION, ... | | 著者 | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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