5AR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ar2 by Molmil](/molmil-images/mine/5ar2) | RIP2 Kinase Catalytic Domain (1 - 310) | 分子名称: | CALCIUM ION, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 | 著者 | Charnley, A.K, Convery, M.A, Lakdawala Shah, A, Jones, E, Hardwicke, P, Bridges, A, Votta, B.J, Gough, P.J, Marquis, R.W, Bertin, J, Casillas, L. | 登録日 | 2015-09-23 | 公開日 | 2015-10-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity. Bioorg.Med.Chem., 23, 2015
|
|
3SEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sep by Molmil](/molmil-images/mine/3sep) | E. coli (lacZ) beta-galactosidase (S796A) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | 登録日 | 2011-06-10 | 公開日 | 2012-01-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
|
|
5I6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i6o by Molmil](/molmil-images/mine/5i6o) | Crystal Structure of Copper Nitrite Reductase at 100K after 20.70 MGy | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRIC OXIDE, ... | 著者 | Horrell, S, Hough, M.A, Strange, R.W. | 登録日 | 2016-02-16 | 公開日 | 2016-07-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. Iucrj, 3, 2016
|
|
5I6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i6p by Molmil](/molmil-images/mine/5i6p) | |
5BV0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bv0 by Molmil](/molmil-images/mine/5bv0) | |
6H0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h0q by Molmil](/molmil-images/mine/6h0q) | B1-type ACP domain from module 7 of MLSB | 分子名称: | Type I modular polyketide synthase | 著者 | Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W. | 登録日 | 2018-07-10 | 公開日 | 2019-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold. Sci Rep, 9, 2019
|
|
6H0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h0j by Molmil](/molmil-images/mine/6h0j) | A1-type ACP domain from module 5 of MLSA1 | 分子名称: | Type I modular polyketide synthase | 著者 | Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W. | 登録日 | 2018-07-09 | 公開日 | 2019-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold. Sci Rep, 9, 2019
|
|
6HC1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hc1 by Molmil](/molmil-images/mine/6hc1) | |
5I6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i6n by Molmil](/molmil-images/mine/5i6n) | Crystal Structure of Copper Nitrite Reductase at 100K after 11.73 MGy | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRIC OXIDE, ... | 著者 | Horrell, S, Hough, M.A, Strange, R.W. | 登録日 | 2016-02-16 | 公開日 | 2016-07-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. Iucrj, 3, 2016
|
|
4OW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ow3 by Molmil](/molmil-images/mine/4ow3) | Thermolysin structure determined by free-electron laser | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION | 著者 | Hattne, J, Echols, N, Tran, R, Kern, J, Gildea, R.J, Brewster, A.S, Alonso-Mori, R, Glockner, C, Hellmich, J, Laksmono, H, Sierra, R.G, Lassalle-Kaiser, B, Lampe, A, Han, G, Gul, S, DiFiore, D, Milathianaki, D, Fry, A.R, Miahnahri, A, White, W.E, Schafer, D.W, Seibert, M.M, Koglin, J.E, Sokaras, D, Weng, T.-C, Sellberg, J, Latimer, M.J, Glatzel, P, Zwart, P.H, Grosse-Kunstleve, R.W, Bogan, M.J, Messerschmidt, M, Williams, G.J, Boutet, S, Messinger, J, Zouni, A, Yano, J, Bergmann, U, Yachandra, V.K, Adams, P.D, Sauter, N.K. | 登録日 | 2014-01-30 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers. Nat.Methods, 11, 2014
|
|
3CB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cb0 by Molmil](/molmil-images/mine/3cb0) | CobR | 分子名称: | 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE, FLAVIN MONONUCLEOTIDE | 著者 | Lawrence, A.D, Warren, M.J, Pickersgill, R.W. | 登録日 | 2008-02-21 | 公開日 | 2008-03-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification, characterization, and structure/function analysis of a corrin reductase involved in adenosylcobalamin biosynthesis J.Biol.Chem., 283, 2008
|
|
3CCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ccw by Molmil](/molmil-images/mine/3ccw) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | 分子名称: | (3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 著者 | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | 登録日 | 2008-02-26 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
5A2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a2s by Molmil](/molmil-images/mine/5a2s) | Potent, selective and CNS-penetrant tetrasubstituted cyclopropane class IIa histone deacetylase (HDAC) inhibitors | 分子名称: | (1S,2S,3S)-1-fluoranyl-2-[4-(5-fluoranylpyrimidin-2-yl)phenyl]-N-oxidanyl-3-phenyl-cyclopropane-1-carboxamide, HISTONE DEACETYLASE 4, SODIUM ION, ... | 著者 | Luckhurst, C.A, Breccia, P, Stott, A.J, Aziz, O, Birch, H, Burli, R.W, Hughes, S, Jarvis, R.E, Lamers, M, Leonard, P, Matthews, K.L, McAllister, G, Pollack, S, Saville-Stones, E, Wishart, G, Yates, D, Dominguez, C. | 登録日 | 2015-05-22 | 公開日 | 2016-02-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Potent, Selective, and Cns-Penetrant Tetrasubstituted Cyclopropane Class Iia Histone Deacetylase (Hdac) Inhibitors. Acs Med.Chem.Lett., 7, 2016
|
|
3T0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t0b by Molmil](/molmil-images/mine/3t0b) | E. coli (LacZ) beta-galactosidase (S796T) IPTG complex | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | 登録日 | 2011-07-19 | 公開日 | 2012-01-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | er-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
|
|
3CD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cd0 by Molmil](/molmil-images/mine/3cd0) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | 分子名称: | (3R,5R)-7-{2-[(4-fluorobenzyl)carbamoyl]-4-(4-fluorophenyl)-1-(1-methylethyl)-1H-imidazol-5-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 著者 | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | 登録日 | 2008-02-26 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
3CD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cd7 by Molmil](/molmil-images/mine/3cd7) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | 分子名称: | (3R,5R)-7-[5-(ANILINOCARBONYL)-3,4-BIS(4-FLUOROPHENYL)-1-ISOPROPYL-1H-PYRROL-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 著者 | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | 登録日 | 2008-02-26 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
3CDB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cdb by Molmil](/molmil-images/mine/3cdb) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | 分子名称: | (3R,5R)-7-{3-[(4-carbamoylphenyl)sulfamoyl]-4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-pyrrol-1-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 著者 | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | 登録日 | 2008-02-26 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
3CDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cda by Molmil](/molmil-images/mine/3cda) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | 分子名称: | (3R,5R)-7-{3-(4-fluorophenyl)-1-(1-methylethyl)-4-phenyl-5-[(4-sulfamoylphenyl)carbamoyl]-1H-pyrrol-2-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 著者 | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | 登録日 | 2008-02-26 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
3D0M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d0m by Molmil](/molmil-images/mine/3d0m) | X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex | 分子名称: | RNA (5'-R(*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3'), SULFATE ION | 著者 | Rypniewski, W, Adamiak, D.A, Milecki, J, Adamiak, R.W. | 登録日 | 2008-05-02 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Noncanonical G(syn)-G(anti) base pairs stabilized by sulphate anions in two X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex. Rna, 14, 2008
|
|
4PJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pjb by Molmil](/molmil-images/mine/4pjb) | Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR | 分子名称: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Birkinshaw, R.W, Rossjohn, J. | 登録日 | 2014-05-12 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J.Exp.Med., 211, 2014
|
|
5OF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5of6 by Molmil](/molmil-images/mine/5of6) | Cu nitrite reductase serial data at varying temperatures 190K 0.48MGy | 分子名称: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | 著者 | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | 登録日 | 2017-07-10 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
|
|
5OFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ofg by Molmil](/molmil-images/mine/5ofg) | Cu nitrite reductase serial data at varying temperatures RT 0.06MGy | 分子名称: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | 著者 | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | 登録日 | 2017-07-11 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
|
|
5OG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5og2 by Molmil](/molmil-images/mine/5og2) | Cu nitrite reductase serial data at varying temperatures RT 0.09MGy | 分子名称: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | 著者 | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | 登録日 | 2017-07-11 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
|
|
4PJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pj5 by Molmil](/molmil-images/mine/4pj5) | |
4PJI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pji by Molmil](/molmil-images/mine/4pji) | |