3K10
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6TL1
| Crystal structure of the TASOR pseudo-PARP domain | Descriptor: | GLYCEROL, Protein TASOR | Authors: | Douse, C.H, Timms, R.T, Freund, S.M.V, Modis, Y. | Deposit date: | 2019-11-29 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control. Nat Commun, 11, 2020
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3J8F
| Cryo-EM reconstruction of poliovirus-receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, ... | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | Deposit date: | 2014-10-20 | Release date: | 2015-02-11 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry. J.Virol., 89, 2015
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3J9F
| Poliovirus complexed with soluble, deglycosylated poliovirus receptor (Pvr) at 4 degrees C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | Deposit date: | 2015-01-15 | Release date: | 2015-02-11 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry. J.Virol., 89, 2015
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6UC8
| Guanine riboswitch bound to 8-aminoguanine | Descriptor: | 8-AMINOGUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Matyjasik, M.M, Hall, S.D, Batey, R.T. | Deposit date: | 2019-09-15 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
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3K0X
| Crystal structure of telomere capping protein Ten1 from Saccharomyces pombe | Descriptor: | IODIDE ION, Protein Ten1 | Authors: | Gelinas, A.D, Reyes, F.E, Batey, R.T, Wuttke, D.S. | Deposit date: | 2009-09-25 | Release date: | 2009-10-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc.Natl.Acad.Sci.USA, 106, 2009
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6UC9
| Guanine riboswitch bound to O6-cyclohexylmethyl guanine | Descriptor: | 6-O-CYCLOHEXYLMETHYL GUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Matyjasik, M.M, Batey, R.T. | Deposit date: | 2019-09-15 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.941 Å) | Cite: | High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
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3KB7
| Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor | Descriptor: | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ... | Authors: | Bossi, R.T, Bertrand, J.A. | Deposit date: | 2009-10-20 | Release date: | 2010-05-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors J.Med.Chem., 53, 2010
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6UBU
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6U0Q
| Transthyretin in complex with (E)-5,5'-(ethene-1,2-diyl)bis(1,1-dihydroxy-3-oxo-1,3-dihydrobenzo[c][1,2]oxaborol-1-uide) | Descriptor: | 3-[(~{E})-2-[7,7-bis(oxidanyl)-9-oxidanylidene-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-3-yl]ethenyl]-7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, Transthyretin | Authors: | Windsor, I.W, Graham, B.J, Raines, R.T. | Deposit date: | 2019-08-14 | Release date: | 2021-01-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Boronic acid with high oxidative stability and utility in biological contexts. Proc.Natl.Acad.Sci.USA, 118, 2021
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6UC7
| Structure of guanine riboswitch bound to N2-acetyl guanine | Descriptor: | COBALT HEXAMMINE(III), N-(6-oxo-6,9-dihydro-3H-purin-2-yl)acetamide, guanine riboswitch | Authors: | Matyjasik, M.M, Batey, R.T. | Deposit date: | 2019-09-15 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
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3L0U
| The crystal structure of unmodified tRNAPhe from Escherichia coli | Descriptor: | MAGNESIUM ION, POTASSIUM ION, Unmodified tRNAPhe | Authors: | Byrne, R.T, Konevega, A.L, Rodnina, M.V, Antson, A.A. | Deposit date: | 2009-12-10 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of unmodified tRNAPhe from Escherichia coli Nucleic Acids Res., 38, 2010
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6USC
| Structure of Human Intelectin-1 in complex with KO | Descriptor: | CALCIUM ION, CHLORIDE ION, Intelectin-1, ... | Authors: | Windsor, I.W, Isabella, C.R, Kosma, P, Raines, R.T, Kiessling, L.L. | Deposit date: | 2019-10-25 | Release date: | 2020-01-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Stereoelectronic Effects Impact Glycan Recognition. J.Am.Chem.Soc., 142, 2020
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3LH1
| Q191A mutant of the DegS-deltaPDZ | Descriptor: | Protease degS | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | Deposit date: | 2010-01-21 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.507 Å) | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
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3LGU
| Y162A mutant of the DegS-deltaPDZ protease | Descriptor: | Protease degS | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | Deposit date: | 2010-01-21 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
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3LGY
| R178A mutant of the DegS-deltaPDZ protease | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Protease degS | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | Deposit date: | 2010-01-21 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
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3LQX
| SRP ribonucleoprotein core complexed with cobalt hexammine | Descriptor: | CHLORIDE ION, COBALT HEXAMMINE(III), POTASSIUM ION, ... | Authors: | Batey, R.T. | Deposit date: | 2010-02-10 | Release date: | 2010-03-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and Energetic Analysis of Metal Ions Essential to SRP Signal Recognition Domain Assembly Biochemistry, 41, 2002
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3LGV
| H198P mutant of the DegS-deltaPDZ protease | Descriptor: | Protease degS | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | Deposit date: | 2010-01-21 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.734 Å) | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
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3LGW
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3LGI
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3LGT
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3LH3
| DFP modified DegS delta PDZ | Descriptor: | Protease degS | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | Deposit date: | 2010-01-21 | Release date: | 2010-08-25 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
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3MMP
| Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | Descriptor: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | Authors: | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | Deposit date: | 2010-04-20 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
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3O1F
| P1 crystal form of E. coli ClpS at 1.4 A resolution | Descriptor: | ATP-dependent Clp protease adapter protein clpS | Authors: | Roman-Hernandez, G, Hou, J.Y, Grant, R.A, Sauer, R.T, Baker, T.A. | Deposit date: | 2010-07-21 | Release date: | 2011-07-27 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease. Mol.Cell, 43, 2011
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8DOV
| Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin | Descriptor: | GLYCEROL, Heme-binding protein Shr, Hemoglobin subunit alpha, ... | Authors: | Macdonald, R, Mahoney, B.J, Cascio, D, Clubb, R.T. | Deposit date: | 2022-07-14 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin. Proc.Natl.Acad.Sci.USA, 120, 2023
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