6CNJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cnj by Molmil](/molmil-images/mine/6cnj) | Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Teng, J, Hibbs, R.E. | 登録日 | 2018-03-08 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557, 2018
|
|
1LDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lda by Molmil](/molmil-images/mine/1lda) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | 分子名称: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | 著者 | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | 登録日 | 2002-04-08 | 公開日 | 2002-05-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science, 296, 2002
|
|
4ZL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zl7 by Molmil](/molmil-images/mine/4zl7) | |
1LDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ldi by Molmil](/molmil-images/mine/1ldi) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | 分子名称: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | 著者 | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | 登録日 | 2002-04-08 | 公開日 | 2002-05-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science, 296, 2002
|
|
6CNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cnx by Molmil](/molmil-images/mine/6cnx) | Crystal Structure of the Human vaccinia-related kinase 1 (VRK1) bound to an N-propynyl-N-isopentyl-dihydropteridin inhibitor | 分子名称: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, (7S)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-8-(3-methylbutyl)-5-(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, ACETATE ION, ... | 著者 | Counago, R.M, dos Reis, C.V, de Souza, G.P, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-09 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Human Vaccinia-Related Kinase 1 (VRK1) bound to a N-propynyl-N-isopentil-dihydropteridine inhibitor To Be Published
|
|
4V5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5l by Molmil](/molmil-images/mine/4v5l) | The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V. | 登録日 | 2010-09-02 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Mechanism for Activation of GTP Hydrolysis on the Ribosome. Science, 330, 2010
|
|
4V5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5r by Molmil](/molmil-images/mine/4v5r) | The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome. | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | 登録日 | 2010-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
|
|
4V5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5g by Molmil](/molmil-images/mine/4v5g) | The crystal structure of the 70S ribosome bound to EF-Tu and tRNA | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | 登録日 | 2009-09-01 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA. Science, 326, 2009
|
|
4V5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5p by Molmil](/molmil-images/mine/4v5p) | The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | 登録日 | 2010-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
|
|
4Z87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z87 by Molmil](/molmil-images/mine/4z87) | Structure of the IMP dehydrogenase from Ashbya gossypii bound to GDP | 分子名称: | ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Buey, R.M, de Pereda, J.M, Revuelta, J.L. | 登録日 | 2015-04-08 | 公開日 | 2015-11-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases. Nat Commun, 6, 2015
|
|
4ZL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zl9 by Molmil](/molmil-images/mine/4zl9) | |
3NTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nth by Molmil](/molmil-images/mine/3nth) | Crystal structure of Tudor and Aubergine [R13(me2s)] complex | 分子名称: | Maternal protein tudor, peptide from Aubergine | 著者 | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | 登録日 | 2010-07-05 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor Genes Dev., 24, 2010
|
|
3OLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3olv by Molmil](/molmil-images/mine/3olv) | |
3OLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oly by Molmil](/molmil-images/mine/3oly) | |
4ZN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zn0 by Molmil](/molmil-images/mine/4zn0) | |
4ZYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zyr by Molmil](/molmil-images/mine/4zyr) | Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG) | 分子名称: | 4-nitrophenyl alpha-D-galactopyranoside, Lactose permease, nonyl beta-D-glucopyranoside | 著者 | Kumar, H, Finer-Moore, J.S, Kaback, H.R, Stroud, R.M. | 登録日 | 2015-05-22 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.312 Å) | 主引用文献 | Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3P22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3p22 by Molmil](/molmil-images/mine/3p22) | Crystal structure of the ENE, a viral RNA stability element, in complex with A9 RNA | 分子名称: | Core ENE hairpin from KSHV PAN RNA, oligo(A)9 RNA | 著者 | Mitton-Fry, R.M, DeGregorio, S.J, Wang, J, Steitz, T.A, Steitz, J.A. | 登録日 | 2010-10-01 | 公開日 | 2010-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Poly(A) tail recognition by a viral RNA element through assembly of a triple helix. Science, 330, 2010
|
|
3OYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oyp by Molmil](/molmil-images/mine/3oyp) | HCV NS3/4A in complex with ligand 3 | 分子名称: | Non-structural protein 4A, Peptidomimetic inhibitor, Serine protease NS3, ... | 著者 | Hagel, M, Niu, D, St.Martin, T, Sheets, M.P, Qiao, L, Bernard, H, Karp, R.M, Zhu, Z, Labenski, M.T, Chaturvedi, P.C, Nacht, M, Westlin, W.F, Petter, R.C, Singh, J. | 登録日 | 2010-09-23 | 公開日 | 2010-12-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine. Nat.Chem.Biol., 7, 2011
|
|
3OOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ooi by Molmil](/molmil-images/mine/3ooi) | Crystal Structure of Human Histone-Lysine N-methyltransferase NSD1 SET domain in Complex with S-adenosyl-L-methionine | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, S-ADENOSYLMETHIONINE, ... | 著者 | Qiao, Q, Wang, M, Xu, R.M. | 登録日 | 2010-08-31 | 公開日 | 2010-12-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation J.Biol.Chem., 286, 2010
|
|
5AC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ac9 by Molmil](/molmil-images/mine/5ac9) | Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design | 分子名称: | VP1, VP2, VP3, ... | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, PerezMartin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | 登録日 | 2015-08-14 | 公開日 | 2015-09-23 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design Nat.Struct.Mol.Biol., 22, 2015
|
|
5BTR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5btr by Molmil](/molmil-images/mine/5btr) | Crystal structure of SIRT1 in complex with resveratrol and an AMC-containing peptide | 分子名称: | AMC-containing peptide, NAD-dependent protein deacetylase sirtuin-1, RESVERATROL, ... | 著者 | Cao, D, Wang, M, Qiu, X, Liu, D, Jiang, H, Yang, N, Xu, R.M. | 登録日 | 2015-06-03 | 公開日 | 2015-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol Genes Dev., 29, 2015
|
|
5BNI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bni by Molmil](/molmil-images/mine/5bni) | Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate | 分子名称: | Uncharacterized protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | 著者 | Ting, K.Y, Leung, C.F.P, Graeff, R.M, Lee, H.C, Hao, Q, Kotaka, M. | 登録日 | 2015-05-26 | 公開日 | 2016-05-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity. Protein Sci., 25, 2016
|
|
2SPM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2spm by Molmil](/molmil-images/mine/2spm) | |
2SPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2spn by Molmil](/molmil-images/mine/2spn) | A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE | 分子名称: | MYOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Quillin, M.L, Arduini, R.M, Phillips Jr, G.N. | 登録日 | 1993-08-25 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate. J.Biol.Chem., 267, 1992
|
|
2SPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2spo by Molmil](/molmil-images/mine/2spo) | |